| #' Compute expected AUROC from R^2 under the liability-threshold model | |
| #' | |
| #' This function implements the closed-form approximation for AUROC given the | |
| #' proportion of variance explained (R^2) on the liability scale and the disease | |
| #' prevalence p. It attempts to follow the liability-threshold/binormal ROC | |
| #' derivation of Wray et al. (2010), *The Genetic Interpretation of Area under | |
| #' the ROC Curve in Genomic Profiling* (PLoS Genetics 6(2): e1000864). | |
| #' | |
| #' In their notation, h2_L (heritability on the liability scale) plays the same | |
| #' mathematical role as the input R^2 here: the variance explained in the latent |
This guide describes how to compile OpenFOAM v2512 natively on Apple Silicon macOS without Docker. The build described here produced native arm64 OpenFOAM binaries using Homebrew GCC and OpenMPI.
The main macOS-specific issue is that OpenFOAM should be built on a case-sensitive filesystem. The default macOS APFS volume is normally case-insensitive, which can cause include collisions such as OpenFOAM's wchar.H versus the system wchar.h.
The approach is: