Assuming that you have a meta box on your post types post.php or post-new.php screen, that has a Nonce value
wp_nonce_field( $this->action, $this->nonce );
and another hidden field that holds the current blog ID
<!-- Retrieve the current blog ID to not save data to the wrong blog per accident. -->
<input type="hidden" name="blog_id" value="<?php print get_current_blog_id(); ?>">
Then you may end up with the following check: