crush_fragmentation.ipynb

{
 "cells": [
  {
   "cell_type": "code",
   "execution_count": 1,
   "id": "b79bd519-dac5-4b85-a406-8d564f937575",
   "metadata": {},
   "outputs": [],
   "source": [
    "from rdkit import Chem\n",
    "from rdkit.Chem.Recap import RecapDecompose\n",
    "from rdkit.Chem.BRICS import BRICSDecompose\n",
    "from rdkit.Chem import Draw\n",
    "from rdkit.Chem.Draw import IPythonConsole"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "id": "52423813-f3ef-4145-a51b-e5459084fa43",
   "metadata": {},
   "outputs": [],
   "source": [
    "import crush_fragmentation"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "7b6b2eb0-eca4-4761-b6d5-12ee82ad504c",
   "metadata": {},
   "outputs": [],
   "source": [
    "mol = Chem.MolFromSmiles(r\"CC1=C[C@H]([C@H]2N(CCC/C=C(/C=C3C)\\OC3=O)CCC2)OC1=O\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "id": "90eb5e73-9fd5-425f-b9a5-d125b01db55d",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<rdkit.Chem.rdchem.Mol at 0x709c362d9a80>"
      ]
     },
     "execution_count": 4,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "mol"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "id": "cb07523d-3cf2-454c-a8d6-ccb723b9e272",
   "metadata": {},
   "outputs": [],
   "source": [
    "res_recap = RecapDecompose(mol)\n",
    "res_brics = BRICSDecompose(mol)\n",
    "res_crush1 = crush_fragmentation.fragment_molecule(mol, modes=['CRUSH'], )\n",
    "res_crush2 = crush_fragmentation.fragment_molecule(mol, modes=['CRUSH'], annotate_cuts=True,random_seed=794, identifier='*')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "id": "18f7ed72-d5a9-44c1-ac24-cb730a0d8f0a",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "\u001b[31mSignature:\u001b[39m\n",
       "crush_fragmentation.fragment_molecule(\n",
       "    smiles: \u001b[33m'MolInput'\u001b[39m,\n",
       "    *,\n",
       "    identifier: \u001b[33m'str | None'\u001b[39m = \u001b[38;5;28;01mNone\u001b[39;00m,\n",
       "    annotate_cuts: \u001b[33m'bool'\u001b[39m = \u001b[38;5;28;01mFalse\u001b[39;00m,\n",
       "    modes: \u001b[33m'tuple[str, ...]'\u001b[39m = (\u001b[33m'RECAP'\u001b[39m, \u001b[33m'BRICS'\u001b[39m, \u001b[33m'CRUSH'\u001b[39m),\n",
       "    min_frag_size: \u001b[33m'int'\u001b[39m = \u001b[32m3\u001b[39m,\n",
       "    protect_neighbor_of_fused: \u001b[33m'bool'\u001b[39m = \u001b[38;5;28;01mTrue\u001b[39;00m,\n",
       "    conservative: \u001b[33m'bool'\u001b[39m = \u001b[38;5;28;01mTrue\u001b[39;00m,\n",
       "    random_seed: \u001b[33m'int | None'\u001b[39m = \u001b[32m42\u001b[39m,\n",
       ") -> \u001b[33m'list[FragmentRecord]'\u001b[39m\n",
       "\u001b[31mDocstring:\u001b[39m <no docstring>\n",
       "\u001b[31mFile:\u001b[39m      ~/dev/CRUSH/src/crush_fragmentation/api.py\n",
       "\u001b[31mType:\u001b[39m      function"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "crush_fragmentation.fragment_molecule?"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "id": "14dbff94-1379-4dc9-8a3a-5ef748a180ca",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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btm3Lli2bN2/92LH8+efcqRM3asSVKrGBwX8J/v33eeHC53++/RbB/dUQ3EuiwYOZiBs14owM3r2bFQo2NuY3XlQFAC1KSEhwd3cXecvT0zMjI+PN98/Ly4uKivLz8xPvlIKNjY3I6+Jd89q1a2lpacy8ZcsWIjIzMzt//nxxPBmQQVZWliapV6pUKTg4WK1WX758uUOHDuJ/387OTvxFoVC4ubmFhIS8c2BVqdjD4/nUGisrbtSoeGZXLliwYN26dXK0bGtrS0SPHz+Wo3HILzMz09nZmYjef//9Z8+evdNj8/L48WO+dIkPHOBDh56ndpWKW7fmWbMQ3F8Bwb3E2bCBidjSki9f5vv32caGiXj+fG2XBQBvolarAwICRDJzdHS8cOHCy/dRqVSRkZE+Pj5ihF6oXr26l5dXaGioWK146dIlf39/McF99erV4oHDhw8nokaNGkk4FQGK340bN9zc3MT/u6ur69WrV48fP64ZYrexsZkwYUJMTEzhO1Cr+csv2dycFQq2sODhw6Wr/bVOnDjRq1cvOX4yGzRoQERXr16VvGXILy8vT5yWVatWraIvhRfBnZlPnGBrawT3V0BwL1Fyrl/nMmWYiFeuZKWS27dnIu7R47/NegFAh128eFEczJR/o3dNXq9cubImr9eoUcPHxycyMlKtVjNzVFTUd999V69evfwTZhYtWiRayMjIaNiwIRGNHj1aa88NJBISEiLGks3MzMSPRMWKFYOCgt56oaZA1GoeNowtLblMGbax4b//lqBNLRGLv48cOaLtQkq4b775RiwnuHjxYtFbW76cly9//ndvb54ypehNljQI7iVHVlaWU8uWO1xc8r78kpl5yhQm4mrVWNKJgwAgq/T09CFDhojw3aVLl88++0xsHCk4Ojr+8MMPZ8+eFXcWE9zFoU5ChQoVxISZnJyc/M1evHhRHCS5bds2bTwtkNKTJ0+++uorzXlD06ZNk7iDiRPZwoKNjblJE05Pl7jxf8XFxQ0cOFCazxuv0qtXLyLasWOHTO0DMy9btoyIjI2NIyIi5Gg/NJT9/eVoWI8huJccI0eOJKI6deqkpqaqIyLYwICNjPjwYW3XBQDvbMuWLe+9917FihU1ed3Pz+/y5cvMnJeXJwbgq1atqsnrtra2Iq+/YXvvwMBAIrK2tsbukCXD4cOHxU/Ijz/+KH3r48axhcVDS8vx/fpJ3zgzM+fk5Kxdu1amxpn5yy+/JKKVK1fK10Upt2vXLkNDQ4VCEVz0M31fJTaWjYzYyIixPCc/BPcSQqw/MzU1jY6Ofvz4sVPdunfbtuWZM7VdFwAU0sKFC4moadOmsbGxnG/CjGYZIhHZ29uLCTN5eXlvbVCtVvfu3ZuIOnToIOG28aBFAQEBRDRmzBg5Gr/ct29DK6vy5cvr6aD1+PHjiWjevHnaLqRkioqKEusrZsyYIV8v33zDROziggm///l/++SDnrp37544RH3BggXNmjUbNGjQmZiYoRYWPHmytksDgEISg6kNGjRwcHB49uxZpUqVOnTosHDhwri4uPr160+ZMuXMmTN3794NDAxs3779C4eevJJCoVixYkWVKlUiIyNnz54t/zMA2YnJ7klJSXI07rh1q+fkyUQ0efJksS26hPz9/TMzM6Vt8wViI9Tk5GRZeymdHj582Lt374yMjM8///yHH36Qr6OZM6lKFTp6lFavlq8TPYPgrlX37tGuXXTmDDEXug2lUvnZZ58lJye7u7uPGjVq7ty5ERERFStWXL16tcLQUMJiAUBbypQp06BBA0dHR19f38jIyGvXrs2ePbtly5bv2o6Njc369esNDQ2nT59+8OBBGSqFYlWhQgWSLbgT0eTJk2fMmJGQkCA2JpLQyJEjLSwspG3zBeKbg+AuubS0tJ49ez58+NDV1XXlypWatRZysLKin38mIpo0iVJS5OtHnxhpu4BSbOFC2rqVevWi7dvp/n3auZNMTArRzOTJk48fP169evXg4OBTp05Nnz7dwMBgzZo1+TeMAwB9t3fvXs3Gf0Xh6urq6+s7Z84cT0/P8+fPi1FJ0FPFMKjs7e1tbGw8efLkdevWDRo06F0fnpaWlpSUlJiYmJycnJycfP369dOnT0+cOLFTp04yFPv/iG+OfJ9qSielUvnpp59euHDB0dFx27ZtL5+NKrlBg+iPP+jAAZo6lRYvlrs3PYDgriVxcbRkCV28+Dys+/jQypU0YsS7NrNnz54FCxYYGRlt3LhRoVAMGDBAqVROnjy5W7du0tdcit24cSMzM7N58+baLgRKL0lSuyCG248dO/b111//9ddfUjULxU/uEXfBy8vL1NTUx8enR48eIg1nZWWlvF5cXNyjR49SUlKSkpJyc3NfbjAyMnL9+vWaQ8dkghF3IqKMDJLupYOIxo4dGx4eXrly5bCwMGtrawlbfoPFi6l5c/rtNxo8mFq3Lp4+dReCu5acP09t2vw3xO7mRjt2UGws/fILmZuTmdnLjxjWuPHBhw9fuPHBgwfMbG1tHRMT8/PPP9+9e7d169bTp0+Xu/zSIyEhYcGCBQEBATk5OY6Ojvv27cu/lQeAPhIf9Zs1a7Z169bly5eLFTKgj4otm3755ZcZGRl169ZNT083MDDIyckp4APLli1bvnx5Gxub8uXLV6hQwczM7MCBA3fu3Pniiy+OHTvm6OgoX82lfcR9/36aPJlsbenxYxowgCZMKHqTM2bMCAoKMjc337ZtW40aNYreYAE5OtI339C8eTRmDJ04QQVY0VOSIbhrz8vz2tVqIqKsLMrKevnujx8+vHXr1itbSkpKEhs/W1tbb9q0ydjYWNJCS6nHjx/7+/svW7YsOzvbwMBAoVBcuXKladOmCxYsELuMFU8N6enp+Y+1LzabN2/28PAo/n6heFSvXn358uUeHh7ffPONs7Nz06ZNtV0RFEbZsmWNjIzS0tKUSqXcr/xr167VfEIwMzOzfr0qVarY2dlZW1vb2NiYvDQFlJkHDRq0YcOGjz766OTJk5o9TyVXqkfcU1NpxAg6fJjs7Cg3lz78kFq2pC5daMUKateOGjQoRPjdtGnTtGnTDAwM1q9f7+zsLEfVb+DnRzt2qC0s9q5a9WTo0MHF3Ltu0fa2NqXVw4dcvz5rdlweP56XLn3+98xMTk5++c/9W7diXxITExMVFVWtWjUiUigU27dv19YTKkkSExP9/PzKli0rvqvu7u7nzp27c+dOnz59xG+Nq6vrjRs3ZK3h2bNnv/zyi9gqpEaNGsW58bZSqfTz8xs1apQ/zr3Qqo0bNxJR//795eti6NChRNSoUSOpDpx/9uyZJO1AwYmNZR4/fixrLydOnDAwMDAyMlq2bFlWVlYRW8vMzBTJz8XFJTs7W5IKX5aenk5ElpaWMrWv0/bu5S+++O/L4GD+3/+YmW1t2dKSjY25WjXu04cnTOC9ezkp6a3tHT58WExnDwwMlK3otwgJ2UpENjY2iYmJ2qpBFyC4a8/cudy9O69YwePHs6srF+HFa8GCBUTUpEkTCasrndLS0vz9/d977z0R0N3c3M6cOZP/DprDxi0sLPz9/eXYDDszM3PevHmiFw0rK6tFixYVZK9uSezfv/+7776Liooqnu7glYohuD979qxBgwYk0Ubgt2/fnjlz5r1794reFBSc+B+8evWqfF0olcpmzZoRkZ+fn1RtxsXF2dvbE9GAAQPUsu3RLbKmfJ8NdNemTTx69H9fbt/Ow4dzSgpXrcpETMRmZmxlxebmbGjIVatykyanmzb19PRcunTpxYsXXzjH7fDhw2Le0bhx44r7ifx/3bt3JyIvLy/tlqFd2gzuKSkpQUFB4myR0igzky9d4rVr+Z9/+PWHHRbE7du3FQqFlZVVaXx5kkhaWtrSpUs1Z8v37Nnz9OnTr7xnUlKSZk5w27ZtxWGWksjJyQkKCtJsB+Ts7Lx169Y7d+54enqKW9q1a3flyhWpunsllUq1ZcuWkJAQpVJ58+ZNWfuCNyuG4M7MFy5cMDMzI6KiX69bt25djx49li1blpOTI0ltUBDt2rUjoiNHjsjXhb+/PxHVrVu36GPt+V26dElc2Jw9e7aEzeYnTit79OiRTO3rruhodnX978uZM/nnn/n6dba2fh7cNX8sLUWCj/53xMrS0tLe3r5169bu7u7e3t7btm0TLxHu7u5aP7jtxo0bpqamBgYGx48f124lWqTgIuwgXjiJiYlhYWGbN2/et2+fsbFxVlbWypUrBw8uZTOW1GqqVYscHGjLFqpQoejttWjR4ty5c3v27BGfR6HgMjMz169fv2jRopSUFGauUaPG7NmzXV1d3/yosLCwkSNH3r9/39jYePz48TNmzHh5KmfBKZXKDRs2TJ8+XSxjaNq06Q8//JB/ivnu3btHjRolVXevxMwRERE//fTTlStXmjVrFhYWJuvuvPBWmzZt+uyzz/r3779p0yZZOwoMDBw3bpyVlVXbtm0NX3P4Q8WKFVUq1Rsa+f77769cuVK1atXLly8PGzZMnkrhFT7++OOdO3eGhob26tVLjvbv3bvn6OiYkZERHh7u5uYmbeOhoaF9+/Zl5q1bI/r06SJt40TUuHHjy5cvX7x4sXHjxpI3rut69KAuXejTT+nCBZoyhSIjSamksWMpL4/y8p7fx9SUjI3JyIgePTqUnf3bv8NGBgYGYhsrc3Pz+Pj4zZs3KxSKhIQEGxsbbT0bjSlTpsydO9fJyenkyZOve70q4YrtI8KNGzd++umntm3bak74MzIysrKyIiJTU9PNmzcXWyU64fBhJuKaNaU6xnfatGlU6q8fvausrKygoKAmTZrY2dnZ2dn17dv3nT7Ep6am+vj4iJ/nxo0bnzx5shA15OXlhYSEaJafNmrUKCQk5JUXjp8+farprkmTJqdOnSpEd6+kVqv37NnTpUsX8X1wdnbeuHFjsU3LgdcpnhF3Zn7w4IG5ublYKvM69evXt3sjWUd84Q3EWvmVK1fK1L74PPBF/gnTkvrll1/atl1gba0+cUL6xjt27EhEhw4dkr5p3ZeTw4GBPHQoT53KRbjmkJ2dLWYcxcXFSVhdoWVkZNSsWZOIlmpWBpYysgf3c+fOff/9940aNdK8AZibm/fp02fVqlWJiYl5eXn/+9//iMjQ0PC3336TuxgdMnYsE/GkSVK1d/78eSKqVKkS8tbr5F82l5ubu2bNmhYtWojM4e7uvm/fvsI1GxkZKeaYGhgYeHl5paenF/CBIrLXq1dP/F40bNgwODj4rRciDx8+XL9+ffG518fHp+hrAQ8fPty9e3fxfXBycvr9998xz0FHFE9wz8vLE8Oobdu23bVr1+7X2LdvX8QbiQtWUPzGjx9PRPPnz5ej8c2bNxORtbW1rItfv/6aibhKFb5/X+KWa9euTUSzZs2SuF3dd+gQd+vG4eGSNCZeIrZu3SpJa0UnTp+Q+8dSZ8kS3FUq1cmTJ2fNmtWuXbsWLVqIXGJtbe3h4REcHJyWlvbC/f39/cVFeV9fXznq0Tl5ec8XiLxmFnXhODg4ENHRo0clbLPEuHr16uzZs69fv56bmxsSEuLs7CyiapcuXUJDQ4u4NCozM9PPz0/sxVarVq3wt71WqtXq0NBQsdiLiGrWrBkUFFTwuYOZmZm+vr7iEqGDg0NEREThyj558uQnn3wivg9NmjRZvHgx1kjolOIJ7rNnzyaiihUrlsZ5wCXCrFmziOj777+XvOXU1FRxbMXy5cslbzy/3Fzu2pWJuHlzLvDQx5ukpqYGBQWJTU4VCoV8lyN016efMhFPmyZJY35+fkT0P7EvjW746KOPiMjOzm706NG+vr7ffvut17/69+/v4eHh4eHh7u7u5ubm5ubWpUsXp3/Vr1/fwcHBwcGhevXq1tbWhoaGdevW1a8Z84UP7mq1etmyZfnHd7Oysv7+++9x48Y5Ojpqrp+2bNnS19c3PDxc+cb1l6tWrTIyMiIib2/vkj9mfOgQE3GtWlLNkxHEuD+2DNkAAB3mSURBVMuECRMkbLPEWL9+fbdu3YKDg4ODgzWRfc+ePRLuZnDu3DknJyfxPuHp6Zn0mg22wsPDW7ZsKSK7vb19UFDQm381Xufs2bOinTd390oHDx709vbWRPagoCBp15yBJIohuJ86dcrY2FihUOzcuVO+XkBWS5cuJaKRI0dK3vKYMWOIqE2bNsXwppyUxPXqMRH37MlFWQB58uTJr776ysLCQrzGVq1adcSIEdKVqScePmRjYzY25gcPJGlv3759ROTs7CxJa5K4ceOG2OhGEo0aNdL2E3oHhQ/uS5cuHTJkyNy5c2/fvr158+Zhw4Y5ODho8nqHDh3mzJkTHR1d8GC0fft2sXJ54MCBubm5hS5MD4wZw0Qs9eWFyMhIIqpdu7a0zZYMGzZsiI6OXrt2bXZ2dv/+/Xfs2CHHW5FSqfT39xc/xpUrV96yZUv+fw0PD2/VqpV4mahWrVpAQEARR7hFd2L2oZ2d3V9//fXWhxw/flwcM16/fv3GjRvPmzfv5StgoCPkDu5Pnz6tVasWPu3rO7F22cPDQ9pmT58+bWhoaGRkdO7cOWlbfp3YWLaxKeR7Y1ZWVnBwsGZMxMDAwM3NLSQkpIRnidf54Qcm4s8/l6q99PR0IyMjY2PjjIwMqdosuujo6B49ekyZMsXf33/+/PlB/9q4cWNISEhISEhoaGh4eHh4eHhERETUv65evSqOwbl7925ycvI///xTpkwZItKjwYvCB/eoqKjAwMBffvklISGhatWqIq+7urrOmzfv+vXrhWvzwIEDYnOorl27ltg8kZfHVaowEUu9SXZeXl7lypWJ6OLFi9K2DO8kJiamc+fO4v3D3d09JiZm//79nTp1ErfY2tr6+/tLOMIdExOjadzDw+N1c/5Onz7ds2dPcbdy5crNmDGjxP6KlRRyB/eBAwcSkZOTE1Y16LXw8HDxpim+jIqKOn36dBG37VOpVCIEF/P81UOH2MSEiTgoqKAPOX+ex4xR2tlV0bzATpo0qVRvZZuTw5UqMRFLul5c/DwcPHhQwjZ1RGBgIBHVqFFDpz6WvEHhg3tWVlZubq5Yivfjjz+uXLlSkhXHUVFR4gDkVq1aPXnypOgN6hx55skIX3/9NRHNmDFD8pbhneTl5S1atEhsmqRha2s7b948qY6ozE+tVgcFBYnurK2tg/7/m96lS5c8PDzEMpIyZcr4+vomJydLXgNITtbg/scff4ifh2vXrsnRPhSb6OhoImrevLn48uOPPyYiS0tLNzc3Pz+/8PDwQlzZ+/XXX4nI3t6++I/C/f13JmITE37zCRnZ2RwSwm5uz/ci79DBy8nJKSgoSI4XWD2zZs3z5QKS8vHxoRK6zFelUjVv3pwkPV9MVrp4cmpsbKzYHa9hw4bSHsKnVCrXr1/ftm1bHx+fgu/+Ia14X1855skIu3fvJqKWLVvK0Ti8q4cPH4oVwwYGBt9//31qaqqs3d2+ffvDDz8UHxK6d+8eExNz5coVT09PsYzVwsLCx8cnPj5e1hpAQjIG92vXDjo7V7OzW716tfSNQ/G6e/euCNniy/Hjx2u2lxXKlCnTrVu32bNnHzlypCBXVx49eiROjw4NDZW59lebMIHnzuWMDNZcmMzK+u9s8evXefx4rlDheWQvV47HjuXLl4t0iGGJ4uzMRLxihbStihlZPXr0kLZZHXH06FGFQmFqalroCSPFSReDOzPHxcWJPTfs7e2LPiCUmZkZGhrq5eUlxvI1axHkDlIvy8vLs7Ozq1+rVvzZs3K0n52dLeYa3bp1S472oRBiYmKKMy6vWrVKLNlRKBRi03czM7Nx48YhsusduYJ7dja3bMlEacOHS9wyaMPTp0+JyMTEZM2aNff/3U8xLi4uJCTEx8fHyckp/0lq5ubmLi4uYseI1w1O9+3bl4g+/fTTYnwSrzBiBLdq9Xyh6owZHBTEmzdz166sUDyP7K1a8YoVrCezG4pLdDQTsbW15N+Xhw8fElHZsmW1fniqTL766isi6tatm7YLeTsdDe7MnJKS0r59eyIqX778sWPHCtFCYmLiqlWrevfubW5unj+vt2vXTkwqeP/99xMSEiSv/A0OHjxIRA4ODhJuZvKCAQMGEFFAQIBM7YPui4+PF/vbmJiYeHl5PZBoYwEoTqmpqeIFUPrgPm4cE3Ht2lzsIxcgufT09F69ehkbG2tONrSzs/Pw8AgKCrp06ZK4T1xc3KZNm0aPHt2oUaP8Id7MzKxjx44//vjjP//8o1nEGRYWRkRWVlZaf90YMYLbt2dxxs6MGbx4MVtZMRGbmbGHh7Tzt0uORxMnsoEBy7Nvo1jLfv78eTka17rExMQKFSoQ0bZt27Rdy1vobnBn5oyMDLFVp6Wl5d9//13AR927dy8oKMjd3V3sqy04Ojr6+flduXJF3OfWrVt169YlogYNGty9e1e2Z/Aib29vIpo8ebJ8XWzYsIGIXF1d5esC9MLZs2f14qofvOz48ePiPTL/okNp7NnDCgUbG7Mcx1RC8bp165Y43NDGxsbb29vd3V1McdGwt7cfPHjwH3/8ERMTIx6SmpoaHh7u6+vr5OSkyfomJiZiWV5GRob4wVu4cKFWnxkz84gRvHMnN27McXE8YwavWMFz5vCiRfz0qbYr01VPnjwxMzNzq1UrMzZWjvY9PT2JaMmSJXI0rguWLFlCRNWrVy/+pR3vRKeDOzOrVKqhQ4eKV5aNGze+4Z6xsbEBAQEuLi6aEQVDQ0MXF5eAgIBXjhzEx8eL5Qh2dnbF8wlSzJMhoujoaPl6SUtLMzMzMzQ0LOaLCQBQdGq1OiAgwMTEhIjEJlHGxsYjR45861EYBRIfz5UrMxH/8osUxYI2HT9+vFKlSkRUr169GzduiBtVKtWlS5eCgoI8PDzE8KFG5cqVPTw8AgICoqKixCXfpKSkHTt2fPvtt8P/nTQ1YcIEInJyctKF6RAjRvD+/bxpEw8a9Dy4w5vNnTuXiHr16iVT+8uWLSOigQMHytS+1uXl5bVu3ZqIpkyZou1a3kTXgzszq9XqiRMnijm7v/766wv/eunSJT8/v4YNG+afw+fu7h4cHPzWI7hTUlI6duxIRNbW1sVw4OiBAwfEPBm5O+rRowcR/fnnn3J3BAASio+P7969u3it8/HxSUpKEudWaoLXqFGjIiIiCpng8/L4gw+YiLt14xJ/yF1Jt3HjRjEFtFu3bm94p4uNjQ0KCvL09Mz/g0RElSpVcnd39/f314R4Zr5w4YKYcnNCN67GiODOzN26cc+eCO5voVKpxNWSgk9PeFcXL14koho1asjUvi44ffq0gYGBiYnJ1atXtV3La+lBcBcCAgLEUPq4ceNUKlVkZKSPj0/+F6MKFSp4enqGhIS80zWO7Ozsfv36idk4YWFh0tYcHR39448/an6LRo8eLfc8GSEoKEjWj90AILm9e/eKIfaKFSuK16L169eLteZly5atWbNm/te6YcOG7d69W/VO+6/PnctEXLEiP3ok13MA+anVaj8/P/Fu6OXlVcADhtRq9aVLlxYvXty/f38xTq9RsWLFTz/9dOrUqdWqVSOib775Ru6nUECa4H79OpuaIri/xbZt24ioTp068h1zq1arxc4H0m73p2vEttpubm7aLuS19Ca4M/Pvv/8uNrbLv7ymZs2a48aNO3ToUKEv7alUquHDh4vZOOvXry9ikXl5eZGRkb6+vvXq1RMVirVlxTNPRoiPjzc0NDQ1NcUJOwB6ICtr6v/+J17Wunfv/vjx48zMTLFrMhF98sknSUlJ/O/VRbHsmIga29qylRW7u3NwML91c1uVitu0YYWC9+wpjmcE8sjKyho0aJCYCBoYGFjodmJjY4ODg728vGrUqJE/xOvUu8bWraw5RmndOj51SqvV6Dw3NzeSf18Ksexww4YNsvaiXUlJSTY2NkQUEhKi7VpeTZ+COzP7+fmJ7O7g4ODr6xsZGSnJ9ixiDEN8JJg/f34hWsjKygoNDR06dKitra3mRbBKlSqjRo06cOAAM+/fv1/ueTKrVq3SrBpxcXEhoi1btsjXHQBI4OpVbt78eocOxsbGfn5+eXl5Z86cER/7zc3NX/k2fOXKlZkzZ+4YOPD5rnhEbGnJ/fvzpk0vJvjUVD55kmNjWa3mnBzW0rbcIIlHjx6JCbhWVlYSHs9+48aNFStWNG3atGnTpkUfupLQ2bPcuDHjOMG3UqvVoaGhCoXCwsJC7sP15syZQ0RjxoyRtRetW758ORFVq1ZNWwf+vJmeBXdmfvr0qUyD1gEBAWKVfcEPeX727FloaKinp6e4oi3UqlXLx8cnMjJSXLG6cOHCjBkzqlevbmho6O7uLkflKSkpYhdIU1NTsYP7jBkziKh58+Zn5dkwHgAk8PvvbGHBRFy37q3oaLEy1dTUlIgaNWp04cKFtzw8NpZ/+un5ULpI8Obm3Ls3r17NGRm8ZQs7ObGvL3t4sLs7v/vxmaA7Lly4IEbHa9WqdfnNZ4qWFAsWMBF/9ZW269BJSqUyKioqICDAw8NDDA8T0ahRo+Tu9/Dhw5TvmN6SKi8vz9nZmYgmTpyo7VpeQf+Cu6xWr14tNpEcMmTIG1aAPXnyJDg42N3dXWz+IIgdJ6Oiopg5Ly/v6NGjEydOzH+CnZmZGRF5enpK+xnu2LFj4nhOKysrcdb9sWPH7O3tLSwsNLOJxAcJCTsFgCJJTWXNkLmnJ6en8+PHvgMHiut+Y8eOzdIcGlkQ9+5xUBC7u7OREROxkRHfucO1a7Nm+O3bb7kIMytAu8LCwsTYUNu2bR8/fqztcopJ795MxKtWabsOnZGYmBgaGjpp0iQXFxfx8V5DjDm+/aN+kWVnZ5uamhoaGj4t6btynjlzxtDQ0MjIqBi+q+8Kwf1FO3fuFKv1+/Tp88J7561bt8SOk5rtb8WOk/7+/mKXXM2q2SpVqmh+ozSrZpcvX16mTBkiqlevniQD4UqlUjN3qHXr1jExMbm5uVOmTBG3NG/e3NPTM/9hsfXr1//hhx9K6ukJAHrj5EmuXZuJ2MqK16xhZo6I4CpVnjk62tvZFemc+bg4/u039vXlU6c4//W9/ftZ8oOcoFhoLgV/9tlnrzvrtORRq7lCBSbi27e1XYp2PXzIISHs48NOTv7OzvmTuqOjo5eXV3Bw8G+//WZqampgYFA8EbNdu3Yk5941ukNsKNKhQwf5TswsHAT3Vzh+/LjYAbdz586p/x4ueO/ePc3vjIWFRZ8+fVatWpWYmMjMGRkZYsJM/sMvatSo4ePj88Luy9euXRObx5uamhZxEcnt27fFRHZDQ0NfX9/c3NyXb+F/F8v6+PiIDStemMxTlAIA4J2p1RwQwMbGTMTvv88xMZyby5MmsYEBE3GXLlkPH0rT0dGj3Lv3f19GRnKfPtK0DMVFqVSK6KBQKPz8/HQtPcjq3Dkm4urVtV1H8VMq+dQp/vVX/vRTtrP7bx0L0Vk3t06dOv3www9hYWGaAe/bt2//8ccfYqZAuXLlDh8+LEdRt2/f/vnnn8XfxfbcU6dOlaMjnfL06VOxp8i6deu0Xcv/g+D+apcuXRJ7TTo5OWlOMurSpcvgwYO3bt0qDplLTEwMDg728PCwtLTMP2Hmzatms7KyNPtF9OnTp3BLSYKDg8Xgvb29/aFDh155ywuQ4AG077PPmIgNDHjSJM7N5du3uV2755Nb/PxYwlNvEhO5dm3W7BX48888bZpkjYP8kpKSunTpIuZY6lpuKAaBgUzEgwdruw65PXzI69fzunV8/z4z89ixbGmZP6xzpUrcty/Pn88nTohfZ80ZW56enprzlTVMTEzWiIt4EsnNzQ0ICBDpYvfu3cy8ZcsWImrYsKGEveisP//8k4gqV66sU1ODFMxM8Cp37tzp1q1bTExM7dq19+7dW7t2bXH73bt3t2/fvmvXroMHD6pUKiIyMDBo0aKFu7v7wIEDNbtAvtm2bduGDRuWkpJib2+/YcMGce2pIFJTU0ePHr1+/Xoi8vDwCAoKMjAweOEWa2vrN7SgVquPHTu2efPmkJCQ+Ph4caODg4O7u7uHh0f79u0LWAkAvLODB+nzz+nPP6lHD9q8mby86OlTqlGD1q0jFxeJ+5o9m6Ki6MsvKTaW1q6lf/6h8uUl7gLkcfPmzV69el27ds3Ozm7Hjh2tWrXSdkXFrV8/2rqV/viDhg7VdinyOX6cvL1pxAhSKOi33ygggEJDacECcnAgFxdq355cXMjRkRQKysigEyfo6NEBp0/vOXQoPT1d04aNjU27du3at2/ftm3bjRs3LlmyRKFQ/Pjjj9OmTSt6gQcOHBgzZsyVK1eIyN3dfenSpVWrVh01atTy5ctNTU2zs7OL3oWOY+bOnTsfOnSoW7duv/76q1ipmJ2dnZWVRURqtTo1NVXc89mzZ0qlkoiUSuWzZ8/EjSLuE1FWVtapU6dq1649d+5c8SmoqGXB68THx7do0YKIbG1tp0yZMmfOHBcXF80u8mZmZm5ubgEBAY8KdaDJ3bt3RV43MjIS28C99SHHjh0Tn7DLli2rWYf6wi0Fp5mRn/88DrHEtpTsWgAgO6WS/f25e3fu3Zs3bmRmzszktDT28no+otavH8u3g9uJExwYyBs2vH2jd9AZkZGRYlvhpk2b3r17V9vlaIFare7VK9DN7dzNm4U6JFhfdOzIUVHP/37+PLdpw48e8b9X+Dk+nkND2deXXVzYxES8XIxr3pyI7OzsPDw8AgIC8h98KwQEBIhFbkOGDCng4Vyv9PDhQ09PT5EK6tWrt2/fPmY+cuRIs2bNxI19Ss3Uu2PHjhU1Z//LxMSke/fuRS8JI+5vkZqa2qNHj+PHj2tusbCw6NKli4eHR58+ffLvAlkIKpVq1qxZM2fOVKvVbm5ua9asyT+P5eV7zpo1Ky8vr3Xr1uvWratZs+YLt+TfweZdy9i/f//mzZu3bduWlJQkbmzUqFH//v0nTJig2Z0GAN7Z2LFUpgxNm0bp6TRoEA0ZQp9/Tp9/Ths3kqUlLVpEX32l7RJBh9y8edPR0VGpVPbp02ft2rX552GWHtevX+/cuXOlSpXOnj2r7VrkVLEiPX5MmgMlK1WiR4/ozz/pyBE6epRiY/+7p5ERtWxJLi6xXbuWef/9F86+fcH27dsHDRqUmZnZtWvXLVu2lCtX7p2KUiqVS5cunTp1anp6uoWFxcSJE6dMmfLs2bPp06cvXrxYrVY7ODjMnDlz4MCB7/x89dbEiRMXLVpUpkwZsY7R1NRU5CKFQqH59lpaWoptBo2NjTVj6u+9955YWW5ubn7+/PmwsLCcnJz9+/d37ty5SAUVPfuXeCkpKa1atSpXrtwHH3zw999/57zTMeMFEB4eLn4PK1WqJD7XvuDWrVtibF6z6vTlWySpRDMGL/aiqVy5cqHPowUAVqm4cuX/JpqfO8eurszMN2+yqytfu6a9ykB3TZ48edKkSfIdXK/7Vq5caWdnN3r0aG0XIrNKlVizd4VazRUrMjPXq/f8WlyZMuziwr6+HBrK7zjB+tSpUyJUNGrU6M6dOwV/4MGDBxs1aiTCobu7+927d/Py8oKDg8VW8SYmJj4+Ps+ePXunYkBj5syZROTo6FjEzIbgrhPu37/fsWNHIjIwMPD19c0fl/fu3Ss+vdWsWfPIkSOcbx1qjRo1ZFpCnpubu2fPnrVr18rROEBpERfHjRv/92VqKteqpb1qAPTDiBEj7OzspF1kqYs+/pg1myru388ffsjMHBTEixbxuXNFXKp++/ZtR0dHMQB3+vTpt97/0aNHnp6eYiZwnTp19uzZw8xnzpxp06aNyPFdu3a9evVqUUqCnJyc+vXrE9Evv/xSlHYQ3HWFSqXSbMreqVOnh//uCpeQkFC5cmUPD4/k5OSnT59+/vnn4rdI3KLdmgHgTZRKtrNjzSTUq1e5XTutFgSgB5o3b25nZ3fz5k1tFyKza9e4RQueNIl9fblFC750Sdrm09LSunfvLmZx7Nix43V3UyqVAQEBYt6vubm5n59fdnZ2cnKyj4+PCCRVq1YNDg6WtrZSa9++fURkZWX14MGDQjeC4K5bDhw4IA5vsrGxEVsvMXNcXBwz79+/v1q1akRUtmzZ1atXa7VMACiYzz/n335jZlap+MsvefFibRcEoNNiYmLs7OyaNWum7UKKRWYmHz/Ox46xPEdrKZVKLy8vMat24cKFL9/h8OHDTZs21cyNuX37tlqtDg4OFsujjY2NfXx8pD3rHfr160dEAwYMKHQLCO46JyEhoUePHmLdg4+PT05OjjghVSxxaNOmTckfhwAoMVJSePhw7tyZO3bkWbOk3KkdoCRavXq1nZ3diBEjtF1IyREQECDmwPj4+ORfOzFy5EjN3JiwsDBmjo6Obtu2rcjxnTt3xv5ycrh//76Y7SzmIxUCgrsuUqvVAQEB4iy0qlWrioF2IyMjCdehAgAA6JoDBw4MGzZs8+bN2i6kRNm0aZPYg7xPnz7iBElmnjlzppgbk5WVlZKSopkbU6VKFcyNkdVPP/1ERA0aNCjcZifYDlJ3nT59unfv3nFxcURkZ2cXEhKC05EAAKAE27x5s4eHh7arKIGOHj3ap0+fxMTE1q1bh4aGVqpUKScn59GjRzVr1lyzZs3EiRMTEhKMjIxGjx49a9YsKysrbddbkuXm5rq5uVlYWPTq1cvb2/tdH47grtNiY2MnTpxIRIsWLapataq2ywEAAJBFYmLismXLHjx40KRJk0KkGXirmzdv9uzZMyYmplatWrt3727YsOH58+e9vb2PHj1KRK6urosXL27cuLG2yywVTpw40a9fPzMzs4MHD1avXv2dHovgDgAAANq3fv36a9euDR06tGbNmtqupWRKSkrq3bv30aNHy5Ur16VLl9DQUJVKZWdnN2/evFJ1ppIuGDVq1I4dO3r27LlixYp3eiCCOwAAAGjfjRs3KleunJWV9ebDQaEoMjMzv/jii23btpmZmalUqtGjR8+cObOIx8BDISQkJHTs2DEtLW3NmjVdu3Yt+AMR3AEAAABKC7VabWNjk5KSEhER8U6REaS1bNmyGTNm1KxZ88CBA6ampgV8lIGsNQEAAACA7lAoFOnp6QqFQhzZDtoyfPhwR0fHO3fuLF26tOCPQnAHAAAAKC2SkpJUKpW1tbXYdRq0xcjIaM6cOQqFYtGiRXfv3i3goxDcAQAAAEqLhIQEIqpYsaK2CwFq3br1J598kp2d7efnV8CHGMlaEAAAAADojidPnhCCu86YOnXqnTt3hg8fXsD7Y8QdAAAAoLQQI+62trbaLgSIiCpWrLhz58727dvHxcVNnz798ePHb74/gjsAAABAaYGpMjpIqVRu2bIlKioqLCzszffEVBkAAACA0gJTZXSQsbGxkZHR+PHj09LS3nxPBHcAAACA0gJTZXTTqFGjCnI3TJUBAAAAKC0wVUavIbgDAAAAlBYI7noNwR0AAACgtMAcd72G4A4AAABQWmCOu15TMLO2awAAAAAA2alUKhMTEwMDg9zcXAMDjN7qH/yfAQAAAJQKCQkJzGxra4vUrqfw3wYAAABQKmBlqr5DcAcAAAAoFbAyVd8huAMAAACUChhx13cI7gAAAAClAraU0XcI7gAAAAClgpgqg+CuvxDcAQAAAEoFTJXRdwjuAAAAAKUCgru+Q3AHAAAAKBWMjY0tLS0xVUZ/4eRUAAAAAAA9gBF3AAAAAAA9gOAOAAAAAKAHENwBAAAAAPQAgjsAAAAAgB5AcAcAAAAA0AMI7gAAAAAAegDBHQAAAABADyC4AwAAAADoAQR3AAAAAAA9gOAOAAAAAKAHENwBAAAAAPQAgjsAAAAAgB5AcAcAAAAA0AMI7gAAAAAAegDBHQAAAABADyC4AwAAAADoAQR3AAAAAAA9gOAOAAAAAKAHENwBAAAAAPQAgjsAAAAAgB5AcAcAAAAA0AMI7gAAAAAAegDBHQAAAABADyC4AwAAAADoAQR3AAAAAAA9gOAOAAAAAKAHENwBAAAAAPQAgjsAAAAAgB5AcAcAAAAA0AMI7gAAAAAAegDBHQAAAABADyC4AwAAAADoAQR3AAAAAAA9gOAOAAAAAKAHENwBAAAAAPQAgjsAAAAAgB5AcAcAAAAA0AMI7gAAAAAAegDBHQAAAABADyC4AwAAAADoAQR3AAAAAAA9gOAOAAAAAKAHENwBAAAAAPQAgjsAAAAAgB74P468ha3CLDbSAAABDHpUWHRyZGtpdFBLTCByZGtpdCAyMDIzLjA5LjYAAHice79v7T0GIOBnQAAeKG5gZGDRAAkw6jACSS02hgQgxcSESWcAaWZmRjYGkHJmFiwCIJWMzDA+B4RmgtHcDIwMjEwMTMxAOSBg1WJiYmLmZmVTYWFj12Bi52Bg51Tg5NJg4uRW4GZVEAG5hpWVjZ2TW3wWyFy4w+ss9x3ovqpjB+LYFk040LNOzh7E5pWNOlBac3IfiC0p+3f/y3XZtiB2pUz8/hsbS/aD2J2y/PbrLRjBbPlnD+2vXNgEZq+VsnfYu5gNzI4V6nXYZ9sAZifbKDm4TksHm78wLNrBTpDdAcReUtVi3/o+CywuBgDgMTYXNypy5gAAAV96VFh0TU9MIHJka2l0IDIwMjMuMDkuNgAAeJx9k11uwyAMgN9zCl+gyDY24Me1qaZpaiJ13e6w991fs1N1pBIaYGTgw/EPmSDadX7//oG/xvM0AeA/w8zgKyPidIFQ4Hh+fVvgdHs5PnZO6+dy+wDiGBj9mX25rZfHDsEVDppMRKkBJiqttuwKbq1fZTjBQZJSNlE/L2RNaQDmAHMSbMgZDpiyZeU2ICVISlarKMa5VhUcgBogplYpDLlmqi3bgCxOYlI1FAlQUWodeVkdpFSLtKzhRLZiNnKyOcjJWkHcolFWy2UAmoMSYYtxWESk1mQAEm4mNcvdkPtach2BBCt4JrlSYb9BhK6PQHbQv+gWLWpn5EGPwPMyP1X//h6O6zL39xCde9V9AbnXllykF5BctJeJXUqvBbnUnnF2aT2v5GI9e7GkfZI4JqJdNmjb4V3YFFPZh7cPJtaPH8P16RewR6T201rdJQAAANp6VFh0U01JTEVTIHJka2l0IDIwMjMuMDkuNgAAeJwdjkFOBEEIRa/isntSjVBAAXZmVVuT8QpjdGdnjNGFyRxecFMhj8f/dZpzPs7zpHqWuc7lfFkv9HBfNoUQ0d4QaLg5t30TUOLQRIPClRIxCDr2tiFwsHZPRhBmUhqqKUckQ3CjWucUqs4JEVQDRYopilkGEtgQT0SZZ23vED7+ha7Bo+1ShRIlIJJ7KcoSknUZNjiP8lPdaLQORChcqZhKlEJZY21t1+/b8fJ1+3xCePs5jt/n6+v7B5zufzwaOxp7B6k/AAAAlHpUWHRyZGtpdFBLTDEgcmRraXQgMjAyMy4wOS42AAB4nHu/b+09BiDgZ0AANiBmBeIGRgYWDZAAow4jkNRiY0gAUkxMuGhU1dwMjAyMTAxMzAzMLAwsrAwiIDnxIJACuEVXTgccWLw/bB+IU7fi236DxE92ILbWe639jQ/W7YOy7YFsO6gae6AasDhQrwNQL1hcDADt3iJiw1r4WAAAAN16VFh0TU9MMSByZGtpdCAyMDIzLjA5LjYAAHicfZFdCsMgDMffPUUuUEn8nI9tLWOMttB1u8Ped38WN6otFKOBqL8Y/1FAsiXe3x/IpqIQAFiZIQR4aUQUI6QAuuF6m6Bf227b6efntD7AgeUMHkeyXedx2yFYoNFSOWUMQYNSYfDEaRJ/VnIV9NCQDMojeT43XutwOQF1AlE65z2pFGlD1voT0jCZwQpnmcuVm0ppx2qymIqWYYqHLvz70s1TLH1JQxXxvABdJBK7KTqI3ZbnErvbF9tfndbbZ3EsvsaSYl7XHr74AAAAjHpUWHRTTUlMRVMxIHJka2l0IDIwMjMuMDkuNgAAeJzTcgYCLYUaDV1jPSMzIxMTHV0DPSMDS3NDUx1rXUM9SyNzAyMdAz0Tc2NjSwugkIGemZm5uaERSJ2xiaGpqbmONVwMIQTTqYvQCrMAbr6mTmJJfm5AUX6BlYFeSmlubqVPYlJqjp6WlSkKtwYAPmom5twZFR8AAAC3elRYdHJka2l0UEtMMiByZGtpdCAyMDIzLjA5LjYAAHice79v7T0GIOBnQAAOKG5gZGDRAAkw6jACSS02hgQgxczIxpABokEMkDQzC0SCkRnG54DQTDCam4GRgZGJgYlZg4mZhYGZVYGVTYOJlV2BnZFBBGQyKyMTMyu7eBbIELgj7JLtHYBuWALiVB/bZw9jB12Xtj8XMtsexA6PDdzPwOAAZu9hZDpw6dYFZPH9SOL7kfSC2WIAZiwjOnFHaIAAAAD4elRYdE1PTDIgcmRraXQgMjAyMy4wOS42AAB4nIVS7WrDMAz876e4F4iR5e+fTVLKGE2gy/YO+9/3Z/JKqgS6TLJAZ86HdNigxW18/77jGTwaA9DBqbXiyxORuaI16M+XtwnDcurXm2H+nJYPFElquWeelvm63jjcwLZWCp7RkaXfgDYrkTHA2fA/0QuRbKKSY5AX7Hzk+IIXhCc6xeXim06OfwjGRmRLXpSSKCbvUi4viGmn2B1IZswbye5AswjzuU13sM55GnfGPqzu52lUq1uyGioAXm0TgKDuOKmoHjSYdFOWyrqOE1h0ZifF28m2czS8fhbpzQ+TMnlUr89rmgAAAJZ6VFh0U01JTEVTMiByZGtpdCAyMDIzLjA5LjYAAHicXcy9CsJAEATgV7G8C3vL7u39xZBqWyG+QkQ7j4hoIeThvSZB7GaYj+mUdVSjVs042YkPq/HY9xQECAbGsEXCRCXHAIyeJQoMjrBwLm3FHFv1SMKSGkjCqfwA9yfcTvZXt91amF9LPT+Xx5Hw+q71c5ovtzt26xfaGyYdP2D/cQAAAS56VFh0cmRraXRQS0wzIHJka2l0IDIwMjMuMDkuNgAAeJx7v2/tPQYg4GdAAF4g5gPiBkYGFg2QAKMOI5DUYmdQAFLMbAwJQIqJCYNWMAGpZWRBMBgyQBqYGdkYQOYws0CUMjLD+BwQmglGczMwMjAyMTAxA+UYWFlYmFjZGNjYGdg5NJg4OBk4uBS4uDWYuHgUWBkZ2HhYGEWYgLpYGZmYWVhZ2dl4uDjEl4GMh/vjjugXe+5u4QMgzndOQQeHqMj9IPb5r5kOZc4T94HY2ezJDrf1ZtuD2O8vsTq80TkJZlf5LrN/lj7DDsT+NNFzX+NLRzDbVbR2/+GrXWBzzlbKHEhebwlmR95NPaAy7waYbZihfIAvwBVszuqPJQeyGU6A2Rt/TNnvybIazBYDAFX4PV3hCBYSAAABgnpUWHRNT0wzIHJka2l0IDIwMjMuMDkuNgAAeJx9k0tOAzEMQPdzCl+gkT+JEy9Y9EeFUKcSFO7AnvsLe6qSqYhIxqOM82LHn5kgxtvh9esbfgcfpgkA/3nMDD4FEaczxAJ2x9PLDPvrdnfX7C8f8/UdSICyn/H5yG6vl/NdQ/AGlAzVqMKGk2ARZcCEy+hHGWbgxKosAhtMLRv66i8osAdJWopyC5CbVGoDMC9gyVUcpMTEonXAFec4oS2hUyqVtI0cq3NuxozFfJutqo78Vuf8XmTasvo+NRs7bjfQWlNU2FBCP5BHJi1ITjlnkxxnKheRURoJA/WwjVRKGFW/L+sIpZvVUoTdqhutWMsocmK4hNHG7hcjR8qFhqQEScmdN4lsinhso5CO8+GhUW6ts7vMh946Mbk3iH+A9DYgl9yLTS6l15S8Xl7Z59OT9AKGsvY6kUvr1WAX6ymnkHViFwWt0sfxIl6liRaNrNIRLjuRF5+ujovROhfryOP7/sP5evoBXxi1kzTwaKYAAAD4elRYdFNNSUxFUzMgcmRraXQgMjAyMy4wOS42AAB4nCWOzUoDQRCEX8Xjbpht+me6Z3pDQBgPHsR48SQeEvSWJUGUIOTh7VkvDf1VFVWbZ2qtvbX7x3f6v23Xhja2Ybcf93R3GwgczTlNDIIqlrYMbMaSJoSaHUXSVsBUbUVcpVDtSHMJjYCJpfQYOsWrhSz04O6cUyS8WCcRJreaLRhVFysr81oNLU0EGJoGY8g5+9pWWEU4WNQ5We62WNs3hU1VYme4ChaV1VU5In2FsVIQAjKpOYiIYUljOnyfl5ev82VG+PhZlt+nw/HzBJt0fZ0NSK4Ps0K+/QGJJERloqmnkwAAAWN6VFh0cmRraXRQS0w0IHJka2l0IDIwMjMuMDkuNgAAeJx7v2/tPQYg4GdAAEEgFgLiBkYGFg2QAKMOI5DUYmNIAFJMTLhodgYFIM2MU5mCCcgsRhYEgyEDpIGZkY0BZA8zC0QpIzOMzwGhmWA0NwMjAyMTAxMzUI6BhZWBlY2BjZ2BnYOBk4OFiZOLgYubgZtHg4mHl4GHT4GPX4OJT0CBk5WBS4CFUYQJaAIrKxs7BycrN5cAH4/4NZBVcD/7bT3sMP+o9AEQx/LZKocK3cn7QWyNi6UO8e+ngdn/jFwcqp9dswWx0/JP2DOfmAVmq6R52btzrbMHsbNvrLc/WK7vAGIfSC212+edB2bzb2zdP2WtDZi9zdRkf2HcPrD6q4eu7/95aosdiL1QZ83+Hyd7wXaZuGoc8GH7CGZ75hsckNGKALuN93bBgaV70sDiW3SWH2j7Mg/MTuzwPrBQ+hvYHDEAqtNR6dtEa5gAAAHSelRYdE1PTDQgcmRraXQgMjAyMy4wOS42AAB4nH2UTW4bMQyF9z4FL+AB/0SKiy5iOwmKIjNA6uYO3ff+KKWpowkgVGMJGvqTRPE9zAlae7/9+P0HPhvfTicA/M8vIuBDEPH0Bm0Cl+fX7ytc70+XR+S6/VrvP4EcqOaafL6yT/ft7REheAdbiEqtDGdeVCTEARfsbSxluEJZRNFQ4UwLaVQuE1ASlKUq1qAOelDFCagdRCtGnH8TaghPuJIcLcVKYN/GS/FZhgZrRj3QmHKBlLAaE877fuLiwcCLK1nVCVeTw4UlTC0TdZZcM+EiubwnqqpZbhhaMWYbEjYyU0QJLZmDVucyuwrRvqfVYtLOlCKUwQnJOylaKOet3ujONkObMimxcTB3DWtNI800JN1RL9aKdJYslxefqUhNngQ8E00grxdIQtMEDDY4lyVPZ/SWACvVqdvSu1vbNZ1D0UTMmtrURc/r7Yuhd4tftvU2LN4eHkbOF5BhV8quw5SUvQzvUXYbFqPsPpxE2eswDGWP4Qtqkqc9Xl6/ycEEPUx0EJv6wAdRuQ0kB+2oD3qQaI+UgxLcBrJDwalH/FDXfvpA6r/DvadJx7Iei9jeH9+YnJ/+AojG4eDwl5xGAAABHnpUWHRTTUlMRVM0IHJka2l0IDIwMjMuMDkuNgAAeJwlkM1KA0EQhF/FYxJmm/7v6SwBYT14EOPFk3iI6M0QESUIeXh7N3NohqKmvurZTHUeqcbLdHv/Stc57abVtJ5Wu/16TzeXlQOR9d4GBhVJbaOBKHobCEizSxsFumLPRYmkPivo5tQQCDWF20hgblkChll4eRAi0ZkagVh6zh4JiWwMoXS1sKSrN4FgkWhjIVBVozypHevRUDlYvaxytAf7YvJuLkUTEyJaJFGr29wRI6p1LeSczLPU+1UI8+IPUkXCZlyBfQYXJZGE5nQDZuUlipW6LjbqyMWrTlV83Q4/p+PT9+lri/D+ezz+PRzePj5h087PW6pPifPdNqFf/gGLvFNEFUoPiwAAAABJRU5ErkJggg==",
      "text/plain": [
       "<IPython.core.display.Image object>"
      ]
     },
     "execution_count": 7,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "Draw.MolsToGridImage([Chem.MolFromSmiles(row) for row in res_recap.GetAllChildren()], molsPerRow=5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "id": "4961d244-b4f8-49da-bfb5-d6e96950950f",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<IPython.core.display.Image object>"
      ]
     },
     "execution_count": 8,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "Draw.MolsToGridImage([Chem.MolFromSmiles(row) for row in res_brics], molsPerRow=5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "id": "649873c7-69b2-47fa-afc4-8b745d95c1fb",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<IPython.core.display.Image object>"
      ]
     },
     "execution_count": 9,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "Draw.MolsToGridImage([Chem.MolFromSmiles(row.fragment_smiles) for row in res_crush1], molsPerRow=5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "id": "c5bd8741-f9b5-479b-8497-3408f77cef33",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<IPython.core.display.Image object>"
      ]
     },
     "execution_count": 10,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "Draw.MolsToGridImage([Chem.MolFromSmiles(row.fragment_smiles) for row in res_crush2], molsPerRow=5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "37820bb6-80e4-44d0-8c4f-4d16078dc47c",
   "metadata": {},
   "outputs": [],
   "source": []
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "Python 3 (ipykernel)",
   "language": "python",
   "name": "python3"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.12.13"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 5
}