This synth's, but it wasn't tested as it turns out you need an instance class with vCPU==4+, which turns out to be quite expensive.
There is some additional nginx config to be done on the instance following provisioning, outlined in these AWS docs starting at point #7:
https://docs.aws.amazon.com/enclaves/latest/user/nitro-enclave-refapp.html#install-acm
This was for a personal project, so I don't particularly see the usefulness of this at this price-point in comparison to using a load balancer, or Letsencrypt with a micro/nano instance.
I'd be interested to hear what applications this might have for those of you looking into this.