The below walkthrough is for those who are running Skyrim SE via Steam Proton, and want to be able to manage mods via Vortex Mod Manager in Linux. You should be able to apply the same walkthrough to Oldrim or Fallout 4 as well. Note that with this guide you'll get an older version of Vortex (1.1.15), but IMHO it is still a better choice than Mod Manager 2. Also, you'll start Skyrim through Steam as usual, not through Vortex.
- If you have previously added mods through the Skyrim game menu, I recommend removing them all since all mods will be managed through Vortex. Mods => Load Order => Delete All. Also, consider taking a backup up your (vanilla) Skyrim game directory.
# archive vanilla game (update path to suit your needs)
cd /mnt/gameData/archive
cp -a /mnt/gameData/SteamLibrary/steamapps/common/Skyrim\ Special\ Edition/. skyrim-se