In networking, a port is a virtual place on a machine that is open to connections from other machines. Every networked computer has a standard number of ports, and each port is reserved for certain types of communication.
Think of ports for ships in a harbor: each shipping port is numbered, and different kinds of ships are supposed to go to specific shipping ports to unload cargo or passengers. Networking is the same way: certain types of communications are supposed to go to certain network ports. The difference is that the network ports are virtual; they are places for digital connections rather than physical connections.
Most of the time, DNS happens over UDP port 53. It's lightweight and faster than TCP. This is to reduce performance overhead on the DNS server due to the number of requests it is likely to receive.
But DNS servers still need to be available on TCP. Zone transfers happen over TCP port 53. This happens on the DNS server side which is not related to the end-user.