directory

| app 
  -- components
  -- models
  -- services
  main.ts
  app.component.ts
| build
  - build.js
  - build.map.js
index.html
system.config
tsconfig.json

system.config

System.config({packages: {app: {format: 'register', defaultExtension: 'ts'}}});
      System.import('build/build.js')
            .then(null, console.error.bind(console));

tsconfig.json

{
  "compilerOptions": {
    "target": "es5",
    "module": "system",
    "moduleResolution": "node",
    "sourceMap": true,
    "emitDecoratorMetadata": true,
    "experimentalDecorators": true,
    "removeComments": false,
    "noImplicitAny": true,
    "suppressImplicitAnyIndexErrors": true,
    "outFile":"./build/build.js",
    "rootDir": "./app/"
  },
  "exclude": [
    "node_modules",
    "typings/main",
    "typings/main.d.ts"
  ]
}