I've had some fun ruining Python recently, but Python is what I use at work. I prefer to use other languages when I'm doing stuff for fun.
And obfuscation only really makes sense in fun and competition - given a suffeciently determined actor, your code will be reverse engineered. Unless you write it in Malboge.
For this particular experiment, I'll be using Lua 5.3. As I'll probably need to dive into some of the less portable functions to commit our atrocities, I can't guarantee it will run on other popular versions like Luajit or 5.1.