While logged in Twitter, go to
https://x.com/settings/your_twitter_data/twitter_interests
You will see a bunch of subjects that Twitter thinks you're interested on. Clicking all the checkboxes manually is a pain in the ass, so...
Open dev tools (F12, command + i, whatever), and go to Network tab to monitor everything
Open the console and run
Array.from(document.querySelectorAll('input[type=checkbox]')).filter(k=>k.checked).forEach(k=>k.click());Wait till it returns to prompt, you'll see a lot of 503 errors. Twitter limit the amount of interaction and put your requests on hold for a while (some seconds or minutes)
Reload the page. Now the list hast quite fewer checked subjects, but if you scroll down, the lasts bunch are still checked. So run the script again, and wait
You might get an error message, like wow, we are superbusy right now and can't comply with your request, so just wait a bit and run it again and again till all the checkboxes are off