Load LayerSlider scripts/styles only when a shortcode is present in the content (can be modified to custom meta, etc).

layerslider-conditional.php

<?php 
/**
 * Load LayerSlider Scripts only when shortcode is present
 *
 * Deregister Scripts from LayerSlider if no shortcode in content
 * Using do_shortcode function? See: http://wordpress.stackexchange.com/questions/20854/conditionally-loading-javascript-css-for-shortcodes/75915#75915
 */
function check_for_layerslider_shortcode() {
    global $post;

    //Check content for layerslider shortcode
    if (!has_shortcode($post->post_content, 'layerslider')) {
        //no shortcode so run deenqueue function
        add_action('wp_print_scripts', 'layerslider_deenqueue_scripts', 99999);
        add_action('wp_print_styles', 'layerslider_deenqueue_scripts', 99999);
    }
}

add_action('wp_enqueue_scripts', 'check_for_layerslider_shortcode');

/**
 * Removes LayerSlider scripts
 */
function layerslider_deenqueue_scripts() {
    wp_dequeue_script('layerslider_js');
    wp_deregister_script('layerslider_js');
    wp_dequeue_script('jquery_easing');
    wp_deregister_script('jquery_easing');
    wp_dequeue_script('transit');
    wp_deregister_script('transit');
    wp_dequeue_script('layerslider_transitions');
    wp_deregister_script('layerslider_transitions');

    wp_dequeue_style('layerslider_css');
    wp_deregister_style('layerslider_css');
    wp_dequeue_style('layerslider_custom_transitions');
    wp_deregister_style('layerslider_custom_transitions');
    wp_dequeue_style('layerslider_custom_css');
    wp_deregister_style('layerslider_custom_css');
}