gistfile1.js

var myConfObj = {
  iframeMouseOver : false
}
window.addEventListener('blur',function(){
  if(myConfObj.iframeMouseOver){
    console.log('Wow! Iframe Click!');
  }
});

document.getElementById('YOUR_CONTAINER_ID').addEventListener('mouseover',function(){
   myConfObj.iframeMouseOver = true;
});
document.getElementById('YOUR_CONTAINER_ID').addEventListener('mouseout',function(){
    myConfObj.iframeMouseOver = false;
});