Nginx example setup for a single page web application with far future expires static content in /static/ and proxying to several backends on any other request that /static or /.

example.server.config

upstream backends {
    ip_hash;

    server 0.0.0.0:80;
    server 0.0.0.0:80;
}

server {
    server_name app.falconsocial.com;

    listen 80; # ipv4

    proxy_read_timeout 3600;
    root /var/www;
    index index.html index.htm;

    error_page 404 /404.html;
    error_page 502 /maintenance.html;
    error_page 500 502 503 504 /50x.html;

    charset utf-8;

    location ^~ /static/ {
        add_header Cache-Control: max-age=31536000;

        # Allow cross origin access
        add_header Access-Control-Expose-Headers "Access-Control-Allow-Origin";
        add_header Access-Control-Allow-Origin "*";
    }

    location ^~ /external/ {
        add_header Cache-Control "max-age=31536000, must-revalidate";
    }

    location ~ ^/.+/ {
        proxy_pass http://backends;
    }

    location / {
        # Force IE into standards compatibility mode
        add_header X-UA-Compatible: "chrome=1;IE=edge"; # Force IE into standards compatible mode

        # Cache forever, but always revalidate
        add_header Cache-Control "max-age=31536000, must-revalidate";
    }
}