Quick sketch of your use case

app.py

from flask import Flask
from flask import request

from twilio import twiml
from twilio.rest import TwilioRestClient

# Declare and configure application
app = Flask(__name__, static_url_path='/static')
app.config.from_pyfile('local_settings.py')

users = [
        '+12152758878',
        '+12153501452',
        '+15855209040']

user_balances = {
        '+12152758878': 0,
        '+12153501452': 25,
        '+15855209040': 1000000}

@app.route('/sms', methods=['POST'])
def sms():
    body = request.form['Body']

    client = TwilioRestClient()

    response = twiml.Response()

    if 'BALANCE' in body:
        trimmed_body = body.replace('BALANCE', '')
        trimmed_body = trimmed_body.strip()
        response.message("User's balance is: %i" % user_balances[trimmed_body])
    else:
        for user in users:
            client.messages.create(from_='+16176069190', to=user,
                    body=body)

    response.message('Message sent.')
    return str(response)
from flask import Flask
from flask import request

from twilio import twiml
from twilio.rest import TwilioRestClient

# Declare and configure application
app = Flask(__name__, static_url_path='/static')
app.config.from_pyfile('local_settings.py')

users = [
        '+12152758878',
        '+12153501452',
        '+15855209040']

user_balances = {
        '+12152758878': 0,
        '+12153501452': 25,
        '+15855209040': 1000000}

@app.route('/sms', methods=['POST'])
def sms():
    body = request.form['Body']

    client = TwilioRestClient()

    response = twiml.Response()

    if 'BALANCE' in body:
        trimmed_body = body.replace('BALANCE', '')
        trimmed_body = trimmed_body.strip()
        response.message("User's balance is: %i" % user_balances[trimmed_body])
    else:
        for user in users:
            client.messages.create(from_='+16176069190', to=user,
                    body=body)

    response.message('Message sent.')
    return str(response)