Example serial script with Flask and Twilio

app.py

from flask import Flask
from flask import request

from twilio import twiml

import serial

# Declare and configure application
app = Flask(__name__, static_url_path='/static')


@app.route('/sms', methods=['POST'])
def sms():
    body = request.form['Body']
    
    ser = serial.Serial('/dev/usb/hiddev0', 9600)
    ser.write(body)

    response = twiml.Response()
    response.message("I sent this to the serial connection: %s" % body)
    return str(response)

if __name__ == "__main__":
    port = 5000
    app.debug = True
    app.run(host="0.0.0.0", port=port)