For best and consistent results, always use Proton as the runner with a supported launcher (Steam as a non-Steam application, or one with an umu backend - e.g. Lutris 0.5.18+, Heroic 2.16.0+, Nero, etc.) - these results may not be reflected properly in Wine for all users!
Warning
JConfig'd games seem to crash on boot (error code 1280) if a configured controller isn't present at runtime.