This Powershell script allows you to apply a Proxy PAC configuration to Chrome, without needing to modify Windows Proxy Settings (or even restarting Windows)

LaunchChromeProxyPac.ps1

##################################################################################
##
## Description : This Powershell script allows you to apply a Proxy PAC configuration to Chrome, without needing to modify Windows Proxy Settings (or even restarting Windows)
##
## Tips : If Chrome Proxy configuration isn't working after launching this script, go to chrome://net-internals/#proxy and "Clear bad proxies"
##
## Usage : Edit $proxyPacURL and launch the script (or make a shortcut with "powershell.exe -noexit -ExecutionPolicy Bypass -File C:\path\to\the\script\LaunchChromeProxyPac.ps1")
##
## Author : Tom-Brian GARCIA ( https://github.com/TBG-FR )
##
##################################################################################

$proxyPacURL = "http://YOUR_URL/proxy.pac";

try
{
    ## Download the Proxy PAC and put its content in a variable
    $proxyPacBytes = (Invoke-webrequest -URI $proxyPacURL).Content;
    Write-Host "Using Proxy PAC from $proxyPacURL.";

    ## Convert Proxy PAC content to Base64
    $proxyPacBase64 = [Convert]::ToBase64String($proxyPacBytes)
    Write-Host "Converted Proxy PAC to a Base64 string of $($proxyPacBase64.Length) characters.";

    ## Launch Chrome with our params
    ## No CORS -> --disable-web-security
    ## Separated session/files -> --user-data-dir="C:/Temp/ChromeDev"
    & 'C:\Program Files\Google\Chrome\Application\chrome.exe' --proxy-pac-url='data:application/x-javascript-config;base64,'$proxyPacBase64;
    Write-Host "Starting Chrome with the Proxy PAC !";

    ## Close terminal
    stop-process -Id $PID;

    exit 0
}
catch
{
    Write-Host "Error: $($_.Exception.Message)";

    exit 1
}