Linux: Disabling Transparent Huge Pages using grubby

thp-off.sh

#!/bin/sh

if [[ $EUID -ne 0 ]]; then
   echo "This script must be run as root" 1>&2
   exit 1
fi

for KERNEL in /boot/vmlinuz-*; do
    grubby --update-kernel="$KERNEL" --args='transparent_hugepage=never'
done

You should also be able to update multiple kernels by running something like this:

grubby --update-kernel=ALL --args="transparent_hugepage=never"