Node.js Readable example

gistfile1.js

// rs is a stream.Readable
rs.on('readable', function () {
  while (true) {
    var chunk = rs.read();
    if (chunk === null) break;
    // do something with chunk
  }
});

I'd consider while (true) to be at least a red flag, if not an outright bug most of the time.

This is somewhat clearer, imo:

var chunk;
while (null !== (chunk = rs.read())) {
  doSomething(chunk);
}

Of course if your goal is just to pull data out asap, you may as well use rs.on('data', function(chunk) { ... }) which basically does exactly that.