Last active
July 6, 2018 17:39
-
-
Save araastat/9927677 to your computer and use it in GitHub Desktop.
Plotting a Kaplan-Meier curve using ggplot. ggkmTable.R adds a table below the plot showing numbers at risk at different times.
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
#’ Create a Kaplan-Meier plot using ggplot2 | |
#’ | |
#’ @param sfit a \code{\link[survival]{survfit}} object | |
#’ @param returns logical: if \code{TRUE}, return an ggplot object | |
#’ @param xlabs x-axis label | |
#’ @param ylabs y-axis label | |
#’ @param ystratalabs The strata labels. \code{Default = levels(summary(sfit)$strata)} | |
#’ @param ystrataname The legend name. Default = “Strata” | |
#’ @param timeby numeric: control the granularity along the time-axis | |
#’ @param main plot title | |
#’ @param pval logical: add the pvalue to the plot? | |
#’ @return a ggplot is made. if returns=TRUE, then an ggplot object | |
#’ is returned | |
#’ @author Abhijit Dasgupta with contributions by Gil Tomas | |
#’ \url{http://statbandit.wordpress.com/2011/03/08/an-enhanced-kaplan-meier-plot/} | |
#’ @export | |
#’ @examples | |
#’ \dontrun{ | |
#’ data(colon) | |
#’ fit <- survfit(Surv(time,status)~rx, data=colon) | |
#' ggkm(fit, timeby=500) | |
#' } | |
ggkm <- function(sfit, returns = FALSE, | |
xlabs = "Time", ylabs = "survival probability", | |
ystratalabs = NULL, ystrataname = NULL, | |
timeby = 100, main = "Kaplan-Meier Plot", | |
pval = TRUE, ...) { | |
require(plyr) | |
require(ggplot2) | |
require(survival) | |
require(gridExtra) | |
if(is.null(ystratalabs)) { | |
ystratalabs <- as.character(levels(summary(sfit)$strata)) | |
} | |
m <- max(nchar(ystratalabs)) | |
if(is.null(ystrataname)) ystrataname <- "Strata" | |
times <- seq(0, max(sfit$time), by = timeby) | |
.df <- data.frame(time = sfit$time, n.risk = sfit$n.risk, | |
n.event = sfit$n.event, surv = sfit$surv, strata = summary(sfit, censored = T)$strata, | |
upper = sfit$upper, lower = sfit$lower) | |
levels(.df$strata) <- ystratalabs | |
zeros <- data.frame(time = 0, surv = 1, strata = factor(ystratalabs, levels=levels(.df$strata)), | |
upper = 1, lower = 1) | |
.df <- rbind.fill(zeros, .df) | |
d <- length(levels(.df$strata)) | |
p <- ggplot(.df, aes(time, surv, group = strata)) + | |
geom_step(aes(linetype = strata), size = 0.7) + | |
theme_bw() + | |
theme(axis.title.x = element_text(vjust = 0.5)) + | |
scale_x_continuous(xlabs, breaks = times, limits = c(0, max(sfit$time))) + | |
scale_y_continuous(ylabs, limits = c(0, 1)) + | |
theme(panel.grid.minor = element_blank()) + | |
theme(legend.position = c(ifelse(m < 10, .28, .35), ifelse(d < 4, .25, .35))) + | |
theme(legend.key = element_rect(colour = NA)) + | |
labs(linetype = ystrataname) + | |
theme(plot.margin = unit(c(0, 1, .5, ifelse(m < 10, 1.5, 2.5)), "lines")) + | |
ggtitle(main) | |
if(pval) { | |
sdiff <- survdiff(eval(sfit$call$formula), data = eval(sfit$call$data)) | |
pval <- pchisq(sdiff$chisq, length(sdiff$n)-1, lower.tail = FALSE) | |
pvaltxt <- ifelse(pval < 0.0001, "p < 0.0001", paste("p =", signif(pval, 3))) | |
p <- p + annotate("text", x = 0.6 * max(sfit$time), y = 0.1, label = pvaltxt) | |
} | |
## Plotting the graphs | |
print(p) | |
if(returns) return(p) | |
} |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
#’ Create a Kaplan-Meier plot using ggplot2 | |
#’ | |
#’ @param sfit a \code{\link[survival]{survfit}} object | |
#’ @param table logical: Create a table graphic below the K-M plot, indicating at-risk numbers? | |
#’ @param returns logical: if \code{TRUE}, return an arrangeGrob object | |
#’ @param xlabs x-axis label | |
#’ @param ylabs y-axis label | |
#’ @param ystratalabs The strata labels. \code{Default = levels(summary(sfit)$strata)} | |
#’ @param ystrataname The legend name. Default = “Strata” | |
#’ @param timeby numeric: control the granularity along the time-axis | |
#’ @param main plot title | |
#’ @param pval logical: add the pvalue to the plot? | |
#’ @return a ggplot is made. if return=TRUE, then an arrangeGlob object | |
#’ is returned | |
#’ @author Abhijit Dasgupta with contributions by Gil Tomas | |
#’ \url{http://statbandit.wordpress.com/2011/03/08/an-enhanced-kaplan-meier-plot/} | |
#’ @export | |
#’ @examples | |
#’ \dontrun{ | |
#’ data(colon) | |
#’ fit <- survfit(Surv(time,status)~rx, data=colon) | |
#' ggkm(fit, timeby=500) | |
#' } | |
ggkmTable <- function(sfit, table=TRUE,returns = FALSE, | |
xlabs = "Time", ylabs = "survival probability", | |
ystratalabs = NULL, ystrataname = NULL, | |
timeby = 100, main = "Kaplan-Meier Plot", | |
pval = TRUE, ...) { | |
require(plyr) | |
require(ggplot2) | |
require(survival) | |
require(gridExtra) | |
if(is.null(ystratalabs)) { | |
ystratalabs <- as.character(levels(summary(sfit)$strata)) | |
} | |
m <- max(nchar(ystratalabs)) | |
if(is.null(ystrataname)) ystrataname <- "Strata" | |
times <- seq(0, max(sfit$time), by = timeby) | |
.df <- data.frame(time = sfit$time, n.risk = sfit$n.risk, | |
n.event = sfit$n.event, surv = sfit$surv, strata = summary(sfit, censored = T)$strata, | |
upper = sfit$upper, lower = sfit$lower) | |
levels(.df$strata) <- ystratalabs | |
zeros <- data.frame(time = 0, surv = 1, strata = factor(ystratalabs, levels=levels(.df$strata)), | |
upper = 1, lower = 1) | |
.df <- rbind.fill(zeros, .df) | |
d <- length(levels(.df$strata)) | |
p <- ggplot(.df, aes(time, surv, group = strata)) + | |
geom_step(aes(linetype = strata), size = 0.7) + | |
theme_bw() + | |
theme(axis.title.x = element_text(vjust = 0.5)) + | |
scale_x_continuous(xlabs, breaks = times, limits = c(0, max(sfit$time))) + | |
scale_y_continuous(ylabs, limits = c(0, 1)) + | |
theme(panel.grid.minor = element_blank()) + | |
theme(legend.position = c(ifelse(m < 10, .28, .35), ifelse(d < 4, .25, .35))) + | |
theme(legend.key = element_rect(colour = NA)) + | |
labs(linetype = ystrataname) + | |
theme(plot.margin = unit(c(0, 1, .5, ifelse(m < 10, 1.5, 2.5)), "lines")) + | |
ggtitle(main) | |
if(pval) { | |
sdiff <- survdiff(eval(sfit$call$formula), data = eval(sfit$call$data)) | |
pval <- pchisq(sdiff$chisq, length(sdiff$n)-1, lower.tail = FALSE) | |
pvaltxt <- ifelse(pval < 0.0001, "p < 0.0001", paste("p =", signif(pval, 3))) | |
p <- p + annotate("text", x = 0.6 * max(sfit$time), y = 0.1, label = pvaltxt) | |
} | |
## Create a blank plot for place-holding | |
## .df <- data.frame() | |
blank.pic <- ggplot(.df, aes(time, surv)) + | |
geom_blank() + | |
theme_bw() + | |
theme(axis.text.x = element_blank(), axis.text.y = element_blank(), | |
axis.title.x = element_blank(), axis.title.y = element_blank(), | |
axis.ticks = element_blank(), panel.grid.major = element_blank(), | |
panel.border = element_blank()) | |
if(table) { | |
## Create table graphic to include at-risk numbers | |
risk.data <- data.frame(strata = summary(sfit, times = times, extend = TRUE)$strata, | |
time = summary(sfit, times = times, extend = TRUE)$time, | |
n.risk = summary(sfit, times = times, extend = TRUE)$n.risk) | |
data.table <- ggplot(risk.data, aes(x = time, y = strata, label = format(n.risk, nsmall = 0))) + | |
#, color = strata)) + | |
geom_text(size = 3.5) + | |
theme_bw() + | |
scale_y_discrete(breaks = as.character(levels(risk.data$strata)), labels = ystratalabs) + | |
# scale_y_discrete(#format1ter = abbreviate, | |
# breaks = 1:3, | |
# labels = ystratalabs) + | |
scale_x_continuous("Numbers at risk", limits = c(0, max(sfit$time))) + | |
theme(axis.title.x = theme_text(size = 10, vjust = 1), panel.grid.major = element_blank(), | |
panel.grid.minor = element_blank(), panel.border = element_blank(), | |
axis.text.x = element_blank(), axis.ticks = element_blank(), | |
axis.text.y = element_text(face = "bold", hjust = 1)) | |
data.table <- data.table + theme(legend.position = "none") + | |
xlab(NULL) + ylab(NULL) | |
data.table <- data.table + | |
theme(plot.margin = unit(c(-1.5, 1, 0.1, ifelse(m < 10, 2.5, 3.5)-0.28 * m), "lines")) | |
## Plotting the graphs | |
## p <- ggplotGrob(p) | |
## p <- addGrob(p, textGrob(x = unit(.8, "npc"), y = unit(.25, "npc"), label = pvaltxt, | |
## gp = gpar(fontsize = 12))) | |
grid.arrange(p, blank.pic, data.table, | |
clip = FALSE, nrow = 3, ncol = 1, | |
heights = unit(c(2, .1, .25),c("null", "null", "null"))) | |
if(returns) { | |
a <- arrangeGrob(p, blank.pic, data.table, clip = FALSE, | |
nrow = 3, ncol = 1, heights = unit(c(2, .1, .25),c("null", "null", "null"))) | |
return(a) | |
} | |
} | |
else { | |
## p <- ggplotGrob(p) | |
## p <- addGrob(p, textGrob(x = unit(0.5, "npc"), y = unit(0.23, "npc"), | |
## label = pvaltxt, gp = gpar(fontsize = 12))) | |
print(p) | |
if(returns) return(p) | |
} | |
} |
Sorry, the code runs well without error but no plot is produced. Can you please help?
I'm getting a plot but the table fails. It seems theme_text() and a number of other calls are deprecated functions in ggplot2? I'll try and trouble shoot it but the solution to change opts_text() from the original statbandit function to theme_text() here is no longer functional. I tried doing the same thing actually before finding this.
I think the "steroids" version of this code is in the survminer, and probably is the one that should be used.
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Sorry, the code runs without a hitch in R but no plot is produced !