Battle tested Nginx config from http://blog.zachorr.com/nginx-setup/

nginx.conf

user www-data;
pid /var/run/nginx.pid;
worker_processes auto;
worker_rlimit_nofile 65000;

events {
    worker_connections 2048;
    multi_accept on;
    use epoll;
}

http {
    sendfile on;
    tcp_nopush on;
    tcp_nodelay on;

    access_log off;
    error_log /var/log/nginx/error.log crit;

    keepalive_timeout 20;
    client_header_timeout 20;
    client_body_timeout 20;
    reset_timedout_connection on;
    send_timeout 20;

    include /etc/nginx/mime.types;
    default_type text/html;
    charset UTF-8;

    gzip on;
    # gzip_static on;
    gzip_proxied any;
    gzip_min_length 256;
    gzip_comp_level 4;
    gzip_types text/plain text/css application/json application/x-javascript text/xml application/xml application/xml+rss text/javascript;

    open_file_cache max=65000 inactive=20s;
    open_file_cache_valid 30s;
    open_file_cache_min_uses 2;
    open_file_cache_errors on;

    include /etc/nginx/conf.d/*.conf;
    include /etc/nginx/sites-enabled/*;
}