HTML5 Boilerplate meets Jade. It was love at first site, with some minor tweaks to give it some spice.

_footer.jade

footer#footer
  // finish it all up with some kinky footer fun
script
  window.jQuery || document.write("<script src='/javascripts/jquery-1.6.2.min.js'>\\x3C/script>")
script
  var _gaq=[['_setAccount','UA-XXXXX-X'],['_trackPageview']];(function(d,t){var g=d.createElement(t),s=d.getElementsByTagName(t)[0];g.src='//www.google-analytics.com/ga.js';}(document,'script'));s.parentNode.insertBefore(g, s)
//if lt IE 7
  script(src="//ajax.googleapis.com/ajax/libs/chrome-frame/1.0.3/CFInstall.min.js")
  script
    window.attachEvent("onload",function(){CFInstall.check({mode:"overlay"})})

_head.jade

meta(charset='utf-8')
link(rel="dns-prefetch", href="//ajax.googleapis.com")
meta(http-equiv='X-UA-Compatible', content='IE=edge,chrome=1')
meta(name='keywords', content='')
meta(name='description', content='')
meta(name='author', content='')
meta(name='viewport', content='width=device-width')
meta(http-equiv='imagetoolbar', content='false')
link(rel='canonical', href='')
script
  TypekitConfig = {
      kitId: 'abc1def'
    }
    (function() {
      var tk = document.createElement('script')
      tk.src = '//use.typekit.com/' + TypekitConfig.kitId + '.js'
      tk.type = 'text/javascript'
      tk.async = 'true'
      tk.onload = tk.onreadystatechange = function() {
        var rs = this.readyState
        if (rs && rs != 'complete' && rs != 'loaded') return
        try { Typekit.load(TypekitConfig); } catch (e) {}
      }
      var s = document.getElementsByTagName('script')[0]
      s.parentNode.insertBefore(tk, s)
    })()
link(rel='stylesheet', href='/assets/stylesheets/app.css')
script(src="/assets/javascripts/head.min.js")
script
  head.js(
    "//ajax.googleapis.com/ajax/libs/jquery/1.7.2/jquery.min.js",
    "/assets/scripts/app.js" )
link(rel="alternate", type="application/rss+xml", title="RSS", href="/feed.rss")
link(rel="author", href="/humans.txt")

_header.jade

header#header
  #logo: a(href="#") Name
  nav#nav
    ul
      li: a(href="#") Link
      li: a(href="#") Link
      li: a(href="#") Link

index.jade

!!! 5
//if lt IE 7
  html.no-js.lt-ie9.lt-ie8.lt-ie7(lang='en')
//if IE 7
  html.no-js.lt-ie9.lt-ie8(lang='en')
//if IE 8
  html.no-js.lt-ie9(lang='en')
//[if gt IE 8]><!
html.no-js(lang='en')
  //<![endif]
  head
    title Page Title &middot; Name
    include _head
  body
    include _header
    section#content
      // have some content
    include _footer