- Masking the mendelian variants / restrict access to particular region of genome
- Aggregate the information to the population level
- Encrypt the data to still keep the patterns but not disclose the raw data
- We might still get privacy concerning information from non-mendelian variants
- Population information might not be relevant for individuals (complex genes interactions, etc)
- Gets in the way of the research, and personalised medicine
- Decrease in cost will make kitchen-sequencing available to anyone (sequence your girlfriend, your employee).
- If we limit the data to a particular institute or research group, they can still leak the data
- Even if it's illegal to sequence you without consent and then later discriminate, companies will do it privately and might not get caught (e.g., http://www.forbes.com/sites/dailymuse/2014/08/04/the-facebook-experiment-what-it-means-for-you/). We would need to verify with an independent entity that there's no discrimination for a particular variant/phenotype, like we nowadays do with gender balance.
- Even if you don't share your data, and don't spread your DNA everywhere (ahah), your data might still be inferred from your relatives (parents, brothers). Can/should you forbid them to share?
- DRM-like technologies to have "privacy" preserved in genomics?
- Laws and policies to prevent/remedy the damage that companies/insurance/rogue individuals might try to cause by discriminating?