An illustration of how stochastic X-chromosome inactivation leads to functional mosaicism.
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#!/bin/sh | |
<<comment | |
REQUIREMENTS: | |
- kubectl (of course) | |
- krew "neat" plugin to remove some extra cruft | |
- yq to decode secrets to stringData | |
The resource types are: |
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### Keybase proof | |
I hereby claim: | |
* I am bpow on github. | |
* I am bpow (https://keybase.io/bpow) on keybase. | |
* I have a public key ASB_4EE6sX3jIuLAkQFDo_M-24lqAxWXNhJjGy_FNzBJugo | |
To claim this, I am signing this object: |
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#!/usr/bin/python | |
from pyld import jsonld | |
import json | |
j = json.loads(''' | |
{ | |
"@context": "http://schema.org/", | |
"@type": "Person", | |
"name": "Jane Doe", |
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{ | |
"cg:id": "VarInterp001", | |
"cg:type": "VariantInterpretation", | |
"variant": { | |
"cg:id": "CanAll035", | |
"cg:type": "CanonicalAllele", | |
"preferredCtxAllele": "CtxAll039", | |
"identifier": "http://reg.genome.network/allele/CA090919" | |
}, | |
"condition": { |
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##fileformat=VCFv4.1 | |
##FORMAT=<ID=AD,Number=.,Type=Integer,Description="Allelic depths for the ref and alt alleles in the order listed"> | |
##FORMAT=<ID=DP,Number=1,Type=Integer,Description="Approximate read depth (reads with MQ=255 or with bad mates are filtered)"> | |
##FORMAT=<ID=GQ,Number=1,Type=Float,Description="Genotype Quality"> | |
##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype"> | |
##FORMAT=<ID=PL,Number=G,Type=Integer,Description="Normalized, Phred-scaled likelihoods for genotypes as defined in the VCF specification"> | |
##INFO=<ID=AC,Number=A,Type=Integer,Description="Allele count in genotypes, for each ALT allele, in the same order as listed"> | |
##INFO=<ID=AF,Number=A,Type=Float,Description="Allele Frequency, for each ALT allele, in the same order as listed"> | |
##INFO=<ID=AN,Number=1,Type=Integer,Description="Total number of alleles in called genotypes"> | |
##INFO=<ID=BaseQRankSum,Number=1,Type=Float,Description="Z-score from Wilcoxon rank sum test of Alt Vs. Ref base qualities"> |
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#!/usr/bin/python | |
import errno | |
import stat | |
import sys | |
import llfuse | |
import time | |
import dxpy | |
import os | |
import json |
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.SECONDARY: | |
LUMPY:=./lumpy-sv | |
YAHADB:=./refs/hg19.X11_01_65525S | |
YAHA:=./yaha | |
BWA:=./bwa-0.6.2/bin/bwa | |
BWADB:=./refs/hg19.fa | |
READ_LENGTH=100 | |
%.um.fq : %.bam |
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#!/bin/bash | |
JAVA_OPTS="-Dgroovy.grape.report.downloads=true" //usr/bin/env groovy "$0" $@; exit $? | |
@GrabResolver(name="maven-sandbox-picard", root="https://github.com/bpow/maven-sandbox/raw/master/picard") | |
@Grab(group="net.sf.picard", module="picard", version="1.86-SNAPSHOT") | |
import net.sf.samtools.* | |
import net.sf.picard.sam.* | |
def mergeAndRemap(chromosome, mapfile, infiles, outfile) { |