This is how to disable the request_finished signal cache close connection behavior in Django.

middleware.py

class DisconnectCacheCloseSignal(object):
    """ Add me to your settings.MIDDLEWARE_CLASSES """
    def process_response(self, request, response):
        from django.core.cache import caches, close_caches
        signals.request_finished.disconnect(caches['default'].close)
        signals.request_finished.disconnect(close_caches)
        return response

A rather large annoyance in my opinion, if you don't need it, drop it! 😛