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codingarchitect / insomnia-disorder-subtypes.md
Created July 23, 2024 09:42
insomnia-disorder-subtypes.md
@codingarchitect
codingarchitect / serotonin-reduction-in-post-acute-sequelae-of-viral-infection-article-summary.md
Last active April 28, 2024 05:04
Serotonin reduction in post-acute sequelae of viral infection - Article Summary

TLDR Version

  • Long COVID is associated with reduced circulating serotonin levels
  • Serotonin depletion is driven by viral RNA-induced type I interferons (IFNs)
  • IFNs reduce serotonin through diminished tryptophan uptake and hypercoagulability
  • Peripheral serotonin deficiency impairs cognition via reduced vagal signaling

Graphical Abstract

Graphical Abstract

@codingarchitect
codingarchitect / long-covid-disease-model-etio-pathogenic-theories.md
Last active April 3, 2024 12:01
Formatted gist from Etiopathogenic theories about long COVID Del Carpio-Orantes L. Etiopathogenic theories about long COVID. World J Virol 2023; 12(3): 204-208 [PMID: 37396704 DOI: 10.5501/wjv.v12.i3.204]
  • Etiopathogenic theories about long COVID, Del Carpio-Orantes L. Etiopathogenic theories about long COVID. World J Virol 2023; 12(3): 204-208 [PMID: 37396704 DOI: 10.5501/wjv.v12.i3.204]
    • Theory of viral persistence or viral particles:
      • There is evidence that after an acute episode of COVID-19, there is persistence of viral particles in various organs up to one year after the episode and the organs mainly affected are: Brain, Gastrointestinal and Hemolymphatic; Similarly, they have been detected in blood, feces and urine
    • Theory of endothelial dysfunction:
      • This theory deals with the damage to the vascular endothelium that leads to endothelitis which, in turn, will favor platelet increase and activation, increased risk of thrombus formation with subsequent damage to organs and tissues by a mechanism of tissue ischemia that can affect the main organs and systems of the human body
    • **Theory of plat
@codingarchitect
codingarchitect / establishing-a-healthy-gut-brain-axis-in after-covid-19.md
Created March 5, 2024 05:06
Establishing a healthy gut brain axis after covid-19 Dr. Leo Galland
  • [[health-and-wellness]] [[long covid]] [[leo-galland]] Establishing a healthy gut brain axis after covid-19
    • TLDW Summary (Level 1):
      • Roadmap to re-establishing a healthy gut-brain axis
        • Step 1: Stop viral proliferation in the gut
        • Step 2: Reduce epithelial cell inflammation (in the gut)
        • Step 3: Reverse gut bacterial dysbiosis created by Covid-19
        • Step 4: Restore transport and metabolism of typtophan
        • Reduce Intestinal permeability
          • Step 5: Restore mucus layer (in the GI Tract)
  • Step 6: Restore tight junction integrity
@codingarchitect
codingarchitect / aws-sigv4-ssm-get-parameter.sh
Last active September 13, 2023 09:36 — forked from slawekzachcial/aws-sigv4-ssm-get-parameter.sh
Using CURL to call AWS ReST API, signing request with v4 signature
#!/bin/bash
# set -x
# Source: https://docs.aws.amazon.com/general/latest/gr/sigv4-signed-request-examples.html
[[ -n "${AWS_ACCESS_KEY_ID}" ]] || { echo "AWS_ACCESS_KEY_ID required" >&2; exit 1; }
[[ -n "${AWS_SECRET_ACCESS_KEY}" ]] || { echo "AWS_SECRET_ACCESS_KEY required" >&2; exit 1; }
readonly method="GET"
readonly service="s3"
readonly region="eu-frankfurt-1"
2021/09/21 07:39:34 [INFO] (telemetry) Starting provisioner powershell
==> oracle-oci: Provisioning with Powershell...
2021/09/21 07:39:34 packer-provisioner-powershell plugin: Found command: & C:\Windows\Panther\Generalize.cmd
2021/09/21 07:39:34 packer-provisioner-powershell plugin: Found command: while($true) { $imageState = Get-ItemProperty HKLM:\SOFTWARE\Microsoft\Windows\CurrentVersion\Setup\State | Select ImageState; if($imageState.ImageState -ne 'IMAGE_STATE_GENERALIZE_RESEAL_TO_OOBE') { Write-Output $imageState.ImageState; Start-Sleep -s 10 } else { break } }
==> oracle-oci: Provisioning with powershell script: /tmp/powershell-provisioner557910254
2021/09/21 07:39:34 packer-provisioner-powershell plugin: Opening /tmp/powershell-provisioner557910254 for reading
2021/09/21 07:39:34 packer-provisioner-powershell plugin: Uploading env vars to c:/Windows/Temp/packer-ps-env-vars-61498a73-f1d0-2cad-3480-cb143477bb4c.ps1
2021/09/21 07:39:34 packer-provisioner-powershell plugin: [INFO] 76 bytes written for '
@codingarchitect
codingarchitect / template.json
Created September 21, 2021 07:28
packer template for windows server 2019 oci packer builder
{
"variables": {
"user_ocid":"{{env `user_ocid`}}",
"tenancy_ocid": "{{env `tenancy_ocid`}}",
"fingerprint":"{{env `fingerprint`}}",
"private_key_path":"{{env `private_key_path`}}",
"private_key_password":"{{env `TF_VAR_private_key_password`}}",
"availability_domain": "uwhB:EU-FRANKFURT-1-AD-1",
"region": "eu-frankfurt-1",
"base_image_ocid": "ocid1.image.oc1.eu-frankfurt-1.redacted",
<Query Kind="Program">
<Reference>&lt;RuntimeDirectory&gt;\System.ServiceModel.dll</Reference>
<Namespace>System.ServiceModel</Namespace>
</Query>
void Main()
{
CallService();
}
@codingarchitect
codingarchitect / WindsorWcfService.linq
Created January 24, 2017 10:55
WindsorWcfService.linq
<Query Kind="Program">
<Reference>&lt;RuntimeDirectory&gt;\Microsoft.CSharp.dll</Reference>
<Reference>&lt;RuntimeDirectory&gt;\System.Runtime.InteropServices.dll</Reference>
<Reference>&lt;RuntimeDirectory&gt;\System.Runtime.InteropServices.WindowsRuntime.dll</Reference>
<Reference>&lt;RuntimeDirectory&gt;\System.Runtime.Serialization.dll</Reference>
<Reference>&lt;RuntimeDirectory&gt;\System.ServiceModel.dll</Reference>
<Reference>&lt;RuntimeDirectory&gt;\System.Web.dll</Reference>
<NuGetReference>Castle.WcfIntegrationFacility</NuGetReference>
<NuGetReference>CodingArchitect.Utilities</NuGetReference>
<NuGetReference>Microsoft.Web.Administration</NuGetReference>