“Force overwrite in the save() method?” <http://librelist.com/browser/wand/2012/12/23/force-overwrite-in-the-save-method/>

gistfile1.py

from wand.image import Image

with Image(file=file) as img:
    x = 275
    y = 275
    img.resize(x, y)
    with open('path/filename_already_exists.png', 'wb') as f:
        img.save(file=f)