The wiredep documentation covers everything in much greater detail but at the most basic...
Install wiredep globally
$ npm install -g wiredepPut commented placeholders in your index.html file
<!-- bower:css -->
<!-- endbower -->
<!-- bower:js -->
<!-- endbower -->Install Bower
Create a bower.json file with bower.init
Use bower install <package> --save to add dependencies
Run wiredep -s index.html