glossary.json

glossary.json

[
  {
    "Feature_title":"Explore and download rodent neuron morphologies",
    "Description":"Thousands of morphology reconstructions available in all common formats",
    "Topic":"Data exploration",
    "Scale":"Cellular",
    "Status":"Available"
  },
  {
    "Feature_title":"Explore and download human neuron morphologies",
    "Description":"Morphology reconstructions of human neurons. From light microscopy or electron microscopy",
    "Topic":"Data exploration",
    "Scale":"Cellular",
    "Status":"Available"
  },
  {
    "Feature_title":"Explore and download validated electrical models for rodent neurons",
    "Description":"Models of the electrical behavior of neurons in five brain regions, including hippocampus and cortex. Validated and used in publications",
    "Topic":"Data exploration",
    "Scale":"Cellular",
    "Status":"Available"
  },
  {
    "Feature_title":"Explore and download validated electrical models for human neurons",
    "Description":"Models of the electrical behavior of specifically human. Cortical neurons. Extensively validated.",
    "Topic":"Data exploration",
    "Scale":"Cellular",
    "Status":"Planned"
  },
  {
    "Feature_title":"Explore and download Blue Brain circuit models",
    "Description":"Simulatable circuit models in SONATA format used in many Blue Brain publications",
    "Topic":"Data exploration",
    "Scale":"Circuit",
    "Status":"Available"
  },
  {
    "Feature_title":"Explore and download simulatable circuit models from the community",
    "Description":"Simulatable circuit models in SONATA format that non-Blue Brain initiatives made openly available",
    "Topic":"Data exploration",
    "Scale":"Circuit",
    "Status":"Available"
  },
  {
    "Feature_title":"Instructive Jupyter notebooks",
    "Description":"To help our useds getting started with the information available on the platform we wrote and curated jupyter notebooks for analysis and educational purposes",
    "Topic":"Analysis",
    "Scale":null,
    "Status":"Available"
  },
  {
    "Feature_title":"Build simulatable single cell models",
    "Description":"Combine reconstructed neuron morphologies and electrical cell models to create a neuron model that can be used in single cell simulations or circuit building",
    "Topic":"Model building",
    "Scale":"Cellular",
    "Status":"Available"
  },
  {
    "Feature_title":"Build and parameterize simulatable synaptome models",
    "Description":"A synaptome model combines a simulatable neuron model with afferent synapses on its dendrites that can be activated at will in simulation campaigns",
    "Topic":"Model building",
    "Scale":"Cellular",
    "Status":"Available"
  },
  {
    "Feature_title":"Simulate single neurons, including synaptomes",
    "Description":"Run simulations of individual neurons directly on the platform and explore and analyze the results",
    "Topic":"Simulation",
    "Scale":"Cellular",
    "Status":"Available"
  },
  {
    "Feature_title":"Study neuron metabolism and its changes during aging",
    "Description":"A recently published, extremely detailed model of the metabolism of a neuron during aging is available on the platform",
    "Topic":"Simulation",
    "Scale":"Subcellular",
    "Status":"Available"
  },
  {
    "Feature_title":"Simulate recordings with extracellular electrodes",
    "Description":"Include the simulation of potentials recorded by extracellular electrodes in your simulation projects and campaigns",
    "Topic":"Simulation",
    "Scale":"Circuit",
    "Status":"Planned"
  },
  {
    "Feature_title":"Simulate calcium sensitive dye imaging",
    "Description":"Include the simulation of the calcium sensitive dye signal in your simulation projects and campaigns",
    "Topic":"Simulation",
    "Scale":"Circuit",
    "Status":"Planned"
  },
  {
    "Feature_title":"Build models of microcircuits and brain regions",
    "Description":"Build new biophysically-detailed models of microcircuits and brain regions based on user-selected data sources . Choose from a range of published algorithms at each step.",
    "Topic":"Model building",
    "Scale":"Circuit",
    "Status":"Planned"
  },
  {
    "Feature_title":"Manipulate and simulate circuit models",
    "Description":"Build variations of existing SONATA circuit models and simulate them to test your theories of circuit function.",
    "Topic":"Analysis",
    "Scale":"Circuit",
    "Status":"Planned"
  },
  {
    "Feature_title":"Run circuit model simulation campaigns",
    "Description":"Parameterize and run complex simulation campaigns for scientific studies. This includes parameter scans and manipulations of any aspect of the model.",
    "Topic":"Simulation",
    "Scale":"Circuit",
    "Status":"In progress"
  },
  {
    "Feature_title":"More powerful and flexible single cell simulations",
    "Description":"New single-cell simulation features include additional stimulation protocols, support for simulation campaigns, e.g., repeating the same protocol on hundreds of neurons, and more control over synaptome activation patterns",
    "Topic":"Simulation",
    "Scale":"Cellular",
    "Status":"In progress"
  },
  {
    "Feature_title":"Extract synaptomes from circuit models ",
    "Description":"Extract individual neurons from any existing circuit model, including its afferent synapses. The resulting synaptome model can be used in simulation campaigns where the experimenter controls activation of the afferent synapses.",
    "Topic":"Model building",
    "Scale":"Cellular",
    "Status":"In progress"
  },
  {
    "Feature_title":"Simulations of paired neurons",
    "Description":"Simulations of paired neurons allow an experimenter full control to study this most fundamental building block of complex brain networks",
    "Topic":"Simulation",
    "Scale":"Cellular",
    "Status":"In progress"
  },
  {
    "Feature_title":"Simulatable circuit models based on data from the MICrONS initiative",
    "Description":"The electron-microscopic reconstruction of mouse brain tissue of the MICrONS initiative is being turned into a simulatable circuit model in SONATA format. Will be constantly refined.",
    "Topic":"Data exploration",
    "Scale":"Circuit",
    "Status":"Planned"
  },
  {
    "Feature_title":"Calibrate circuit models to an in vivo-like state",
    "Description":"Calibrate a model of compensation for missing extrinsic inputs to ensure its biorealistic activity state. Includes validations against reference data (spiking, LFP, EEG, etc.)",
    "Topic":"Model building",
    "Scale":"Circuit",
    "Status":"Planned"
  },
  {
    "Feature_title":"Improved download options for single cell scale models and simulation results",
    "Description":"Download single cell and synaptome models also in SONATA format for easy use with any compatible simulator. Also download single cell simulation results in SONATA format for compatibility with existing analysis packages.",
    "Topic":"Data exploration",
    "Scale":"Cellular",
    "Status":"In progress"
  },
  {
    "Feature_title":"Manipulate single cell models to test hypotheses of cellular function",
    "Description":"Build variations of existing single cell models and simulate them to test your theories of neuron function.",
    "Topic":"Analysis",
    "Scale":"Cellular",
    "Status":"Planned"
  },
  {
    "Feature_title":"Explore and download validated ion channel models",
    "Description":"Find and download ion channel models from a vast library of models",
    "Topic":"Data exploration",
    "Scale":"Subcellular",
    "Status":"Planned"
  },
  {
    "Feature_title":"Build, optimize and validate electrical models from raw data",
    "Description":"Build an electrical model of a neuron that recreates the features and behavior from experimental recordings, such as spike rate and shape. Use your own experimental recordings or select from publicly available ones.",
    "Topic":"Model building",
    "Scale":"Cellular",
    "Status":"Planned"
  },
  {
    "Feature_title":"Run jupyter notebooks directly on the platform",
    "Description":"Run analyses of neurons, circuits, models or simulations directly on the platform. Share the results with your collaborators.",
    "Topic":"Analysis",
    "Scale":null,
    "Status":"In progress"
  },
  {
    "Feature_title":"Complex connectomics analyses of circuit wiring diagrams",
    "Description":"Run complex analyses of circuit connectivity on the platform to link circuit structure to its function. Select from a library of analyses that have been successfully used in past publications.",
    "Topic":"Analysis",
    "Scale":"Circuit",
    "Status":"Planned"
  }
]