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{ | |
"$schema": "https://raw.githubusercontent.com/jsonresume/resume-schema/v1.0.0/schema.json", | |
"basics": { | |
"name": "Daniel Polanco", | |
"label": "Bioinformatician | Software Developer | Cloud Engineer", | |
"email": "[email protected]", | |
"phone": "+1 (719) 422 3765", | |
"url": "https://daniel.polanco.me", | |
"summary": "Bioinformatician with over 10 years experience in automating pipelines and deploying production-ready applications. Skilled in cloud engineering, workflow automation, and software development. Dedicated to mentoring and leading software development teams, with a passion for public health genomics and clinical research collaboration.", | |
"location": { | |
"city": "Denver", | |
"countryCode": "US", | |
"region": "Colorado" | |
}, | |
"profiles": [ | |
{ | |
"network": "GitHub", | |
"username": "danpolanco", | |
"url": "https://github.com/danpolanco" | |
}, | |
{ | |
"network": "Linkedin", | |
"username": "danpolanco", | |
"url": "https://www.linkedin.com/in/danpolanco" | |
} | |
], | |
"meta": { | |
"theme": "macchiato" | |
} | |
}, | |
"work": [ | |
{ | |
"name": "State of Colorado", | |
"position": "Bioinformatician", | |
"startDate": "2022-11-01", | |
"summary": "Bioinformatician for the Colorado Department of Public Health and Environment (CDPHE) Genomics Surveillance Program (GSP). Focused on clinical pathogen sequencing, variant analysis, and automated epidemiological reporting for public health surveillance.", | |
"highlights": [ | |
"Process and analyze over 7,000 COVID-19 patient samples using WDL workflows for pathogen detection and variant calling.", | |
"Develop and implement RSV genomic surveillance workflow, analyzing 674 samples across three respiratory seasons for clinical insights.", | |
"Support 23-person genomics surveillance team with 40TB+ cloud storage infrastructure growing at 0.5TB monthly.", | |
"Design event-driven architecture with Pub/Sub for automatic load distribution and Cloud Functions auto-scaling to handle variable genomic data processing workloads.", | |
"Implement Infracost cost estimation and storage lifecycle policies for cloud resource optimization and budget planning.", | |
"Mentor team members on Terraform infrastructure development and provide code reviews for BigQuery/Dataform implementations.", | |
"Perform quality control and variant interpretation using IGV, validating genomic data for clinical accuracy and GISAID repository submissions.", | |
"Migrate weekly variant proportion reporting to cloud native solutions for public health decision-making and outbreak response.", | |
"Submit pathogen genomes to clinical repositories including Biosample, SRA, GenBank, and GISAID following quality assurance protocols.", | |
"Maintain compliance with PII/PHI protection standards and internal SOPs for clinical data handling and privacy protocols.", | |
"Collaborate directly with clinicians on research projects, including RSV genomic diversity analysis presented at APHL conference.", | |
"Collaborate with CDC and APHL on multiple projects including AIMS Influenza Sequencing Center and IT Security and Privacy white papers.", | |
"Design, implement, and automate BigQuery data extract, load and transformation for disease surveillance using Dataform for reproducibility and stability.", | |
"Configure and build out Google Cloud infrastructure with enhanced security protocols for clinical and wastewater data processing." | |
] | |
}, | |
{ | |
"name": "Jonah Ventures", | |
"position": "Software Engineer", | |
"startDate": "2022-08-01", | |
"endDate": "2022-11-01", | |
"summary": "Worked as a software engineer for Jonah Ventures, a startup focused on developing innovative solutions for environmental genomics.", | |
"highlights": [ | |
"Prototyped a sample management system for use by laboratory technicians.", | |
"Expanded skills in R, R Markdown, R Shiny, AWS, SQL and related technologies to support environmental genomics projects." | |
] | |
}, | |
{ | |
"name": "Atelier Circle", | |
"position": "Founder & Software Engineer", | |
"startDate": "2018-04-01", | |
"endDate": "2022-10-01", | |
"summary": "Founded Atelier Circle, a software company focused on innovative solutions for clinical research.", | |
"highlights": [ | |
"Collaborated with the Colorado Center for Personalized Medicine to prototype iMTracker (lifestyle tracking app) on iOS for a pilot study.", | |
"Reviewed project specifications and implemented industry standard solutions to met end user expectations.", | |
"Worked with field experts to design user-interfaces that are engaging, simple, and informative for non-technical users while maintaining consent for research purposes.", | |
"Introduced agile methodologies and development best practices to codebase to streamline product development." | |
] | |
}, | |
{ | |
"name": "Stantec", | |
"position": "Innovation Engineer", | |
"startDate": "2016-10-01", | |
"endDate": "2017-08-01", | |
"summary": "Worked as an Innovation Engineer at Stantec, a global engineering and design firm. Focused on developing innovative solutions for environmental and infrastructure projects.", | |
"highlights": [ | |
"Created a holographic mobile app for HoloLens using Git, Visual Studio Team Services, and Agile methodology.", | |
"Built and deployed the app on Azure (Microsoft's cloud service) for Stantec while incorporating Practice Technology Director's feedback." | |
] | |
}, | |
{ | |
"name": "University of Colorado", | |
"position": "Teaching Assistant", | |
"startDate": "2011-08-01", | |
"endDate": "2013-04-01", | |
"summary": "Worked at the University of Colorado Denver as a teaching and laboratory assistant.", | |
"highlights": [ | |
"Assisted in teaching undergraduate courses in general biology and genetics.", | |
"Lead laboratory sessions, helping students with experiments and data analysis.", | |
"Graded assignments and provided feedback to students to enhance their learning experience." | |
] | |
}, | |
{ | |
"name": "University of Colorado", | |
"position": "Research Assistant", | |
"startDate": "2010-08-01", | |
"endDate": "2016-04-01", | |
"summary": "Worked as a Research Assistant at the University of Colorado Anschutz Medical Campus, focusing on bioinformatics, evolutionary genomics, and computational biology.", | |
"highlights": [ | |
"Conducted DNA/RNA laboratory work and bioinformatics programming for genomic data analysis on model organisms and clinical patient samples.", | |
"Contributed to computational biology research that resulted in PNAS publication on Burmese python genome analysis." | |
] | |
} | |
], | |
"education": [ | |
{ | |
"institution": "University of Colorado", | |
"url": "https://www.cuanschutz.edu/", | |
"area": "Biomedical Sciences and Biotechnology", | |
"studyType": "Master", | |
"startDate": "2015-01-01", | |
"endDate": "2017-01-01", | |
"score": "3.7" | |
}, | |
{ | |
"institution": "University of Colorado", | |
"url": "https://www.ucdenver.edu/", | |
"area": "Biology", | |
"studyType": "Bachelor", | |
"startDate": "2009-01-01", | |
"endDate": "2013-01-01", | |
"score": "3.9" | |
}, | |
{ | |
"institution": "Arapahoe Community College", | |
"url": "https://www.arapahoe.edu/", | |
"area": "Arts", | |
"studyType": "Associate", | |
"startDate": "2005-01-01", | |
"endDate": "2009-01-01", | |
"score": "3.8" | |
} | |
], | |
"awards": [ | |
{ | |
"title": "Summa Cum Laude", | |
"date": "2023-08-01", | |
"awarder": "University of Colorado", | |
"summary": "Bachelor of Science" | |
} | |
], | |
"certificates": [ | |
{ | |
"name": "Google Cloud Engineering Course", | |
"issuer": "Google Cloud", | |
"summary": "Currently completing Google Cloud Engineering course with planned certification exam" | |
} | |
], | |
"publications": [ | |
{ | |
"name": "Evaluation of RSV Genomic Diversity and Variant Prevalence Across Three Respiratory Seasons in Pediatric Cases in Colorado", | |
"publisher": "APHL", | |
"releaseDate": "2024-01-01", | |
"url": "https://www.aphl.org/conferences/annualmeeting/Documents/AC24_Final_Program.pdf", | |
"summary": "Optimized WGS method and analyzed 674 distinct RSV samples using bioinformatics workflow. Evaluated prevalence of A and B subtypes and clades across three respiratory seasons, performing phylogenetic comparisons to determine circulating variants in Colorado over time. Demonstrated seasonal subtype alternation: B dominant in 2021, A in 2022, returning to B in 2023." | |
}, | |
{ | |
"name": "The Burmese python genome reveals the molecular basis for extreme adaptation in snakes", | |
"publisher": "PNAS", | |
"releaseDate": "2013-12-02", | |
"url": "https://www.pnas.org/doi/10.1073/pnas.1314475110", | |
"summary": "By analyzing the genomes and gene expression of the Burmese python and other snakes, we found that extensive genetic and transcriptional adaptations underlie snakes' extreme physiological traits, revealing system-wide changes in metabolism, organ function, and genome structure that provide insights relevant to vertebrate biology and medicine." | |
} | |
], | |
"skills": [ | |
{ | |
"name": "Bioinformatics", | |
"level": "", | |
"keywords": [ | |
"Clinical Genomics", | |
"Data Visualization", | |
"IGV", | |
"Next-Generation Sequencing (NGS)", | |
"Phylogenetic Analysis", | |
"Pipeline Development", | |
"Python", | |
"Quality Control", | |
"R", | |
"Tableau", | |
"Variant Analysis", | |
"WDL Workflows" | |
] | |
}, | |
{ | |
"name": "Cloud", | |
"level": "", | |
"keywords": [ | |
"Auto Scaling", | |
"Cost Management", | |
"Data Warehousing", | |
"Disaster Recovery", | |
"Google Cloud Platform (GCP)", | |
"Load Balancing", | |
"Microservices", | |
"Monitoring", | |
"Security", | |
"Serverless", | |
"Storage", | |
"Terraform" | |
] | |
}, | |
{ | |
"name": "General", | |
"level": "", | |
"keywords": [ | |
"AI", | |
"Automation", | |
"Bash", | |
"Docker", | |
"Git", | |
"PowerShell", | |
"Python", | |
"R", | |
"Shell Scripting" | |
] | |
}, | |
{ | |
"name": "GitOps", | |
"level": "", | |
"keywords": [ | |
"GitHub Actions", | |
"Continuous Deployment (CD)", | |
"Continuous Integration (CI)", | |
"Infrastructure as Code (IaC)" | |
] | |
}, | |
{ | |
"name": "Statistical Analysis", | |
"level": "", | |
"keywords": [ | |
"Complex Data Manipulation", | |
"Pandas", | |
"Plotly", | |
"Report Generation", | |
"Statistical Graphics", | |
"Data Analysis" | |
] | |
} | |
], | |
"languages": [ | |
{ | |
"language": "English", | |
"fluency": "Native" | |
}, | |
{ | |
"language": "Spanish", | |
"fluency": "Elementary" | |
} | |
], | |
"interests": [ | |
{ | |
"name": "Culture", | |
"keywords": [ | |
"Anime and Manga", | |
"Electronic Music", | |
"Indie Pop and Rock", | |
"Food and Cuisine", | |
"Science Fiction and Fantasy", | |
"Cooperative Multiplayer Games" | |
] | |
}, | |
{ | |
"name": "Weightlifting", | |
"keywords": [ | |
"Balance and Coordination", | |
"Functional Fitness", | |
"Injury Prevention", | |
"Mental Toughness", | |
"Powerlifting", | |
"Progressive Overload", | |
"Strength and Conditioning", | |
"Supplementation" | |
] | |
} | |
], | |
"projects": [ | |
{ | |
"name": "CDPHE GSP | GCP Infrastructure", | |
"startDate": "2025-02-10", | |
"description": "Automates and manages Google Cloud infrastructure with Terraform modules including integrated cost estimation. (Private repository)", | |
"highlights": [ | |
"Designed and implemented modular Terraform infrastructure for a GCP-based sequencing data pipeline, supporting creation, ingestion, preparation, and processing stages.", | |
"Developed secure, team-based access controls using IAM roles and Google Secret Manager for sensitive credentials and configuration.", | |
"Automated provisioning and management of Google Cloud resources, including Cloud Storage buckets, Pub/Sub topics and subscriptions, Cloud Run jobs/services, and Cloud Scheduler jobs.", | |
"Integrated external APIs (e.g., BaseSpace, workflow platforms) into cloud-native data workflows for scientific data processing.", | |
"Enabled cost estimation and optimization using Infracost to provide detailed monthly breakdowns for cloud resources.", | |
"Established a GitHub-based CI/CD workflow with automated versioning, PR checks, and release management using GitHub Actions.", | |
"Documented infrastructure modules and workflows with clear diagrams (Mermaid) and compatibility matrices to support maintainability and cross-team collaboration.", | |
"Implemented environment-specific (dev/prod) infrastructure with parameterized modules for flexible deployments." | |
] | |
}, | |
{ | |
"name": "CDPHE GSP | Inbox Handler", | |
"startDate": "2024-10-29", | |
"description": "Automate processing raw instrument data into a cloud storage inbox.", | |
"highlights": [ | |
"Developed and maintained cloud-native Python functions for automated sequencing data processing using Google Cloud Functions and Pub/Sub.", | |
"Designed robust data ingestion pipelines for Illumina and Oxford Nanopore sequencing platforms, integrating with Google Cloud Storage and Firestore.", | |
"Implemented dynamic workbook discovery and download logic from Google Cloud Storage, supporting both project and run-level organization.", | |
"Built modular utilities for handling large-scale genomic data, including sample sheet creation, fastq file validation, renaming, and cloud uploads.", | |
"Integrated Google Cloud Tasks for scalable, asynchronous sample processing workflows.", | |
"Utilized environment-driven configuration management for seamless deployment across development and production environments.", | |
"Leveraged pandas for efficient parsing and manipulation of sequencing metadata and sample workbooks.", | |
"Implemented error handling and logging best practices to ensure traceability and reliability in cloud workflows.", | |
"Collaborated on a multi-platform codebase supporting both Illumina BaseSpace and ONT instrument data extraction and transformation.", | |
"Contributed to CI/CD and local testing workflows, including environment setup scripts and automated deployment pipelines." | |
], | |
"url": "https://github.com/CDPHE-bioinformatics/inbox-handler" | |
}, | |
{ | |
"name": "CDPHE GSP | Sequencer Utility", | |
"startDate": "2024-08-27", | |
"description": "Automate sequencing instrument import into the cloud environment.", | |
"highlights": [ | |
"Designed and implemented modular Terraform infrastructure for a GCP-based sequencing data pipeline, supporting creation, ingestion, preparation, and processing stages.", | |
"Developed secure, team-based access controls using IAM roles and Google Secret Manager for sensitive credentials and configuration.", | |
"Automated provisioning and management of Google Cloud resources, including Cloud Storage buckets, Pub/Sub topics and subscriptions, Cloud Run jobs/services, and Cloud Scheduler jobs.", | |
"Integrated external APIs (e.g., BaseSpace, workflow platforms) into cloud-native data workflows for scientific data processing.", | |
"Enabled cost estimation and optimization using Infracost to provide detailed monthly breakdowns for cloud resources.", | |
"Established a GitHub-based CI/CD workflow with automated versioning, PR checks, and release management using GitHub Actions.", | |
"Documented infrastructure modules and workflows with clear diagrams (Mermaid) and compatibility matrices to support maintainability and cross-team collaboration.", | |
"Implemented environment-specific (dev/prod) infrastructure with parameterized modules for flexible deployments." | |
], | |
"url": "https://github.com/CDPHE-bioinformatics/sequencer-utility" | |
}, | |
{ | |
"name": "CDPHE GSP | Workflow Operator", | |
"startDate": "2024-04-30", | |
"description": "Automate the analysis of sequencing data using cloud-native workflows.", | |
"highlights": [ | |
"Developed and maintained a cloud-native bioinformatics workflow operator using Python and Google Cloud Functions.", | |
"Designed and implemented robust REST API integrations with Google Cloud services, including Secret Manager, Storage, and Pub/Sub.", | |
"Automated deployment pipelines using GitHub Actions, including version bumping, code analysis (mypy, ruff), and CI/CD workflows.", | |
"Built modular, type-annotated Python code leveraging dataclasses, enums, and dependency injection for configuration management.", | |
"Implemented secure handling of secrets and environment variables for multi-environment (dev/prod) deployments.", | |
"Created reusable utility functions for dynamic dataset management, including creation, lookup, and upload to cloud platforms.", | |
"Integrated with Google Cloud Storage for automated retrieval and processing of large-scale sequencing data files.", | |
"Utilized pandas for efficient data manipulation and transformation within cloud functions.", | |
"Enabled local and remote testing and deployment with custom Bash scripts and VS Code task automation.", | |
"Documented development and deployment processes for team onboarding and operational transparency." | |
], | |
"url": "https://github.com/CDPHE-bioinformatics/workflow-operator" | |
} | |
] | |
} |
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