Top 100 of most downloaded packages on PyPI as of 2015-04-10.

gistfile1.txt

+-----+-----------------+-----------------+
|   # | Package Name    | Total Downloads |
+-----+-----------------+-----------------+
|   1 | setuptools      |      52,454,151 |
|   2 | requests        |      42,297,369 |
|   3 | virtualenv      |      38,499,034 |
|   4 | distribute      |      36,848,278 |
|   5 | six             |      34,594,923 |
|   6 | boto            |      33,578,502 |
|   7 | pip             |      29,951,145 |
|   8 | certifi         |      29,214,833 |
|   9 | wincertstore    |      26,167,852 |
|  10 | pbr             |      23,887,223 |
|  11 | python-dateutil |      22,952,946 |
|  12 | lxml            |      21,928,901 |
|  13 | nose            |      20,394,779 |
|  14 | pytz            |      19,076,100 |
|  15 | simplejson      |      18,587,517 |
|  16 | Jinja2          |      16,228,908 |
|  17 | pika            |      16,049,431 |
|  18 | PyYAML          |      15,585,882 |
|  19 | docutils        |      14,665,876 |
|  20 | MarkupSafe      |      14,242,028 |
|  21 | Django          |      14,087,702 |
|  22 | pyasn1          |      13,778,285 |
|  23 | paramiko        |      12,774,019 |
|  24 | coverage        |      12,117,867 |
|  25 | pycrypto        |      11,803,986 |
|  26 | psycopg2        |      11,629,825 |
|  27 | colorama        |      10,214,880 |
|  28 | zc.buildout     |      10,063,765 |
|  29 | argparse        |       9,661,209 |
|  30 | Paste           |       9,590,378 |
|  31 | rsa             |       9,528,834 |
|  32 | botocore        |       9,416,721 |
|  33 | ssl             |       9,315,084 |
|  34 | supervisor      |       9,197,215 |
|  35 | awscli          |       9,140,041 |
|  36 | redis           |       9,132,736 |
|  37 | selenium        |       9,129,952 |
|  38 | jmespath        |       9,111,169 |
|  39 | SQLAlchemy      |       9,048,774 |
|  40 | pymongo         |       8,993,094 |
|  41 | ecdsa           |       8,970,491 |
|  42 | bcdoc           |       8,748,032 |
|  43 | mock            |       8,722,114 |
|  44 | meld3           |       8,643,891 |
|  45 | httplib2        |       8,637,133 |
|  46 | pep8            |       8,444,841 |
|  47 | PasteDeploy     |       8,376,996 |
|  48 | Werkzeug        |       8,327,577 |
|  49 | Pygments        |       8,195,989 |
|  50 | cffi            |       7,965,467 |
|  51 | carbon          |       7,482,832 |
|  52 | MySQL-python    |       7,421,896 |
|  53 | Flask           |       7,318,349 |
|  54 | graphite-web    |       6,872,207 |
|  55 | kombu           |       6,535,707 |
|  56 | pycparser       |       6,503,708 |
|  57 | greenlet        |       6,334,738 |
|  58 | anyjson         |       5,975,068 |
|  59 | Fabric          |       5,935,979 |
|  60 | zope.interface  |       5,901,020 |
|  61 | Pillow          |       5,642,854 |
|  62 | Sphinx          |       5,576,727 |
|  63 | setuptools-git  |       5,534,746 |
|  64 | numpy           |       5,370,535 |
|  65 | beautifulsoup4  |       5,246,934 |
|  66 | South           |       5,148,113 |
|  67 | celery          |       5,070,824 |
|  68 | Babel           |       5,022,051 |
|  69 | docopt          |       5,009,229 |
|  70 | py              |       4,940,337 |
|  71 | amqp            |       4,912,110 |
|  72 | itsdangerous    |       4,882,379 |
|  73 | gunicorn        |       4,593,466 |
|  74 | tornado         |       4,583,094 |
|  75 | PrettyTable     |       4,480,809 |
|  76 | Mako            |       4,448,763 |
|  77 | psutil          |       4,446,795 |
|  78 | WebOb           |       4,420,551 |
|  79 | iso8601         |       4,403,113 |
|  80 | pyOpenSSL       |       4,375,162 |
|  81 | pyparsing       |       4,364,419 |
|  82 | ipython         |       4,166,400 |
|  83 | isodate         |       4,156,257 |
|  84 | billiard        |       4,080,477 |
|  85 | pyflakes        |       4,054,853 |
|  86 | ordereddict     |       4,013,900 |
|  87 | unittest2       |       3,962,749 |
|  88 | gevent          |       3,927,709 |
|  89 | logilab-common  |       3,705,419 |
|  90 | Twisted         |       3,685,023 |
|  91 | jsonschema      |       3,659,816 |
|  92 | pylint          |       3,609,053 |
|  93 | cryptography    |       3,606,864 |
|  94 | stevedore       |       3,602,229 |
|  95 | pycups          |       3,451,492 |
|  96 | decorator       |       3,322,822 |
|  97 | pytest          |       3,277,356 |
|  98 | flake8          |       3,104,197 |
|  99 | ply             |       3,086,039 |
| 100 | urllib3         |       3,026,283 |
+-----+-----------------+-----------------+