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WikiPathway: Retinoblastoma gene in cancer

PMID Proteins Year Title
30773851 24 2019 Retinoblastoma mutation predicts poor outcomes in advanced non small cell lung cancer.
36399634 28 2023 Retinoblastoma Expression and Targeting by CDK46 Inhibitors in Small Cell Lung Cancer.
38034873 38 2023 Ropivacaine inhibits the malignant behavior of lung cancer cells by regulating retinoblastoma-binding protein 4.
17804741 3 2007 Retinoblastoma deficiency increases chemosensitivity in lung cancer.
25162518 31 2014 Retinoblastoma binding protein 2 (RBP2) promotes HIF-1alpha-VEGF-induced angiogenesis of non-small cell lung cancer via the Akt pathway.
21511813 26 2011 MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells.
25609198 21 2015 The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma protein.
36044718 4 2022 Immune Checkpoint Blockade Outcome in Small-Cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function.
21676486 5 2011 Expression and function of retinoblastoma binding protein 6 (RBBP6) in human lung cancer.
25607217 5 2015 Role of adenovirus-mediated retinoblastoma 94 in the treatment of human non-small cell lung cancer.
8052667 6 1994 Cyclin D1 overexpression vs. retinoblastoma inactivation: implications for growth control evasion in non-small cell and small cell lung cancer.
9393586 4 1997 Differential expressions of cyclin A and the retinoblastoma gene product in histological subtypes of lung cancer cell lines.
9816293 2 1996 Differential expression of the retinoblastoma gene family members pRbp105, p107, and pRb2p130 in lung cancer.
8971152 3 1996 Altered p16INK4 and retinoblastoma protein status in non-small cell lung cancer: potential synergistic effect with altered p53 protein on proliferative activity.
11679179 3 2001 Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II.
8263009 4 1994 Gene analysis of K-, H-ras, p53, and retinoblastoma susceptibility genes in human lung cancer cell lines by the polymerase chain reactionsingle-strand conformation polymorphism method.
17143528 2 2007 Dexamethasone inhibits paclitaxel-induced cytotoxic activity through retinoblastoma protein dephosphorylation in non-small cell lung cancer cells.
11410775 2 2001 Prognostic significance of p21waf1, cyclin D1 and retinoblastoma expression detected by immunohistochemistry in non-small cell lung cancer.
8645257 2 1996 UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line.
10910097 2 2000 Src family kinase activity is required for Kit-mediated mitogen-activated protein (MAP) kinase activation, however loss of functional retinoblastoma protein makes MAP kinase activation unnecessary for growth of small cell lung cancer cells.
10574258 2 1999 Predictive value of expression of p16INK4A, retinoblastoma and p53 proteins for the prognosis of non-small-cell lung cancers.
9815783 2 1997 Prognostic significance of cyclin D1 and retinoblastoma expression in combination with p53 abnormalities in primary, resected non-small cell lung cancers.
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