Symbolicates a sample dump from Activity Monitor

symbolicate-sample-dump.py

#!/usr/bin/env python

#
# To use this, just put the DSYMS in the same directory as the sample dump file, 
# and run the script from that directory, passing the sample dump file name as only argument
# 

import re, sys, os, subprocess

sampleFile = sys.argv[1]
for sampleLine in open(sampleFile, 'r').readlines():
    match = re.search(r'\?{3}\s*\(in\s+(.*?)\)\s+load address\s*([\d\w]+).*\[([\d\w]+)\]', sampleLine)
    if match:
        binary = match.group(1)
        loadAddress = match.group(2)
        offset = match.group(3)
        script = "atos -arch x86_64 -o {0}.*.dSYM/Contents/Resources/DWARF/{1} -l {2} {3} > temp".format(binary, binary, loadAddress, offset)
        os.system(script)
        method = open('temp', 'r').read()
        sampleLine = sampleLine.replace(r'???', method)
    print sampleLine,

If you are on macOS Sonoma, there is a symbolicate button in Sample window. You can symbolicate the sample from there.