A snippet of my addon build script that I use to automate publishing new versions.

upload_addon.py

from glob import glob
import io
import os
import time
import uuid
from zipfile import ZipFile
# third party libraries
import jwt  # PyJWT
import requests
# get API keys from https://addons.mozilla.org/developers/addon/api/key/
#  and put them into a .env file like so:
# jwt-issuer=string
# jwt-secret=string


GUID = 'GUID GOES HERE'  # make sure to include the '{' and '}' if your GUID has it
addon_files = ['manifest.json', 'style.css'] + glob('icons/*.png')

# read environmental variables
with open('.env') as f:
    line = f.readline()
    while line:
        k, v = line.split('=', 1)
        os.environ[k] = v.strip()
        line = f.readline()


def create_zip(file):
    """ file: filename or file-type object """
    with ZipFile(file, 'w') as zf:
        for file in addon_files:
            zf.write(file)


def upload(version):
    # e.g. version = '1.1.1.1'

    # create auth JWT token
    jwt_secret = os.environ['jwt-secret']
    jwt_issuer = os.environ['jwt-issuer']
    jwt_obj = {
        'iss': jwt_issuer,
        'jti': str(uuid.uuid4()),
        'iat': time.time(),
        'exp': time.time() + 60
    }
    jwt_obj = jwt.encode(jwt_obj, jwt_secret, algorithm='HS256').decode()

    file = io.BytesIO()
    create_zip(file)
    print(f'uploading version {version}')
    data = {'upload': ('manifest.zip', file.getvalue()), 'channel': 'listed'}
    headers = {'Authorization': f'JWT {jwt_obj}'}
    url = f'https://addons.mozilla.org/api/v4/addons/{GUID}/versions/{version}/'
    r = requests.put(url, data, headers=headers, files=data)
    print(r.status_code)
    print(r.json())