An Apple Silicon ISCE2 install can be done, but it is a bit tricky. In short, the key is to:
Install ISCE2 via conda/mamba within an osx-64 environment
The osx-64 component is key because as of late 2024, ISCE2 does not distribute an arm-based build via condaforge.
Note that ISCE2 may be slower than you expect because it has to run via the Rosetta 2 translation tool.