README.md

Genomic unknowns in RefSeq genomes

We will screen the RefSeq genomes for genoimc unknowns. We will use the non-redundant set of genomes identified by MASH+t-SNE+PAM clustering.

Preparing RefSeq data

cd /bioinf/home/afernand/SANDBOX/unk_vs_refseq/
mkdir genomes
rsync -Pauvz  /bioinf/projects/megx/UNKNOWNS/chiara/NETWORK/RefSeq82.ref.gen/proteomes/downloads/ genomes/
find genomes/ -name '*gz' \
    | while read file; do NAM=$(basename $file _protein.faa.gz); zcat $file \
        | mawk -vL=$NAM '$0 ~/^>/{gsub(">", "", $0); print L"\t"$0}'; done >> all_refseq82_nr_names.tsv

And rename the headers:

mkdir genomes_renamed
cd genomes_renamed
parallel -j 252 --progress ../rename_headers.sh ::: /bioinf/home/afernand/SANDBOX/unk_vs_refseq/genomes/*faa

cd ..
find genomes_renamed/ -name '*.faa' \
    | while read line; do printf "/bioinf/home/afernand/SANDBOX/unk_vs_refseq/genomes_renamed/$line\n"; done > genomes_list.txt

find genomes/ -name '*gz' \
    | while read file; do NAM=$(basename $file _protein.faa.gz); zcat $file | mawk -vL=$NAM '$0 ~/^>/{gsub(">", "", $0); print L"\t"$0}'; done >> all_refseq82_nr_names.tsv

Preparing profiles for MMSEQS2

We need the ffindex files with the HHM profiles, and convert them to MMSEQS2 format. First we copy the HHM profiles to scratch and we convert them:

mkdir /scratch/antonio/mmseqs2_profiles
cd /scratch/antonio/mmseqs2_profiles

cp /bioinf/projects/megx/UNKNOWNS/2017_11/classification/results/ffindex_data/marine_hmp_db_03112017_gu_hhm.ffdata marine_hmp_db_03112017_gu_hhm

cp /bioinf/projects/megx/UNKNOWNS/2017_11/classification/results/ffindex_data/marine_hmp_db_03112017_gu_hhm.ffindex marine_hmp_db_03112017_gu_hhm.index

~/opt/MMseqs2_uv/build/bin/mmseqs convertprofiledb marine_hmp_db_03112017_gu_hhm marine_hmp_db_03112017_gu_hhm_profileDB --threads 16

Once we have them converted we move them to the shared file system, we will use start the jobs in the clusters. One job per genome.

mv *profile* /bioinf/home/afernand/SANDBOX/unk_vs_refseq/
cd /bioinf/home/afernand/SANDBOX/unk_vs_refseq/
rm -rf /scratch/antonio/mmseqs2_profiles

We might need to redo the symlinks to the seq_h files

rm marine_hmp_db_03112017_gu_hhm_profileDB_seq_h
ln -s /bioinf/home/afernand/SANDBOX/unk_vs_refseq/marine_hmp_db_03112017_gu_hhm_profileDB_h marine_hmp_db_03112017_gu_hhm_profileDB_seq_h
ln -s /bioinf/home/afernand/SANDBOX/unk_vs_refseq/marine_hmp_db_03112017_gu_hhm_profileDB_h.index marine_hmp_db_03112017_gu_hhm_profileDB_seq_h.index

Using the HPC cluster

We will start an array in the cluster to process each genome independently

mkdir /bioinf/home/afernand/SANDBOX/unk_vs_refseq/results
qsub gu_vs_refseq_sge.sh

Needs to be in any of the machines with access to the cluster (sunrays, linux-desktop, arb-servers)

Parse and plot the results

Once the search is done we will combine results

parallel -j 252 --progress cat {} > gu_vs_refseq82.tsv ::: results/*m8
cut -f 16- -d " " gu_vs_refseq82.tsv > tmp
paste <(cat gu_vs_refseq82.tsv | cut -f 1-15 -d " " | tr " " $'\t') tmp > gu_vs_refseq82_tab.tsv

and parse the hypotheticals and get the taxonomies:

bash ~/opt/scripts/hypo_parse.sh gu_vs_refseq82_tab.tsv ~/opt/scripts/unknown_grep.tsv gu_vs_refseq82_hypo.tsv
cp /bioinf/projects/megx/UNKNOWNS/chiara/NETWORK/RefSeq82.ref.gen/genomes_taxonomy.tsv.gz .

For plotting use the script here

gu_vs_refseq_sge.sh

#!/bin/bash
#$ -S /bin/bash
#$ -j y
#$ -pe threaded 4
#$ -cwd
#$ -R y
#$ -N gu_vs_r82
#$ -cwd
#$ -P megx.p
#$ -t 1-10604

G=$(awk -vT=$SGE_TASK_ID "NR==T" /bioinf/home/afernand/SANDBOX/unk_vs_refseq/genomes_list.txt)
/bioinf/home/afernand/SANDBOX/unk_vs_refseq/mmseqs_gu.sh $G

hypo_parse.sh

#!/bin/bash
set -x

FILE=${1}
PATTERNS=${2}
FOUT=${3}

if [ -f ${FOUT} ]; then
    rm ${FOUT}
fi

LC_ALL=C rg -j 4 -i -f ${PATTERNS} ${FILE} | awk '{print $0"\thypo"}' > ${FOUT}
LC_ALL=C rg -j 4 -v -i -f ${PATTERNS} ${FILE} | awk '{print $0"\tchar"}' >> ${FOUT}

mmseqs_gu.sh

#!/bin/bash
source ~/opt/scripts/activate_mpi
set -x
TSV="/bioinf/home/afernand/SANDBOX/unk_vs_refseq/all_refseq82_nr_names.tsv"
PROF="/bioinf/home/afernand/SANDBOX/unk_vs_refseq/marine_hmp_db_03112017_gu_hhm_profileDB"

# Get representative
# Get cluster num
scratch=$(mktemp -d -p /scratch/tmp)
function finish {
  rm -rf "$scratch"
}
trap finish EXIT

#MD5=$(md5sum <(echo "$SEQS") | awk '{print $1}')

#N=$(LC_ALL=C grep -m 1 "${MD5}" "${TSV}" | cut -f2)

TMP=$(mktemp -d -p ${scratch})

cd $scratch


N=$(basename $1 .faa)

MMSEQS=~/opt/MMseqs2/build/bin/mmseqs
${MMSEQS} createdb $1 ${N}_db
${MMSEQS} search ${PROF} ${N}_db ${N}_results ${TMP} -c 0.8 --cov-mode 0 -e 1e-5 --threads ${NSLOTS}
${MMSEQS} convertalis ${PROF} ${N}_db ${N}_results ${N}_results.m8 --format-mode 2

join -1 2 -2 2 <(~/opt/coreutils/bin/sort -k2,2 ${N}_results.m8) <(LC_ALL=C grep -F $N $TSV | ~/opt/coreutils/bin/sort -k2,2 --parallel=$NSLOTS) > tmp && mv tmp ${N}_results.m8

rm -rf ${TMP} ${N}_db* *index

mv *m8 /bioinf/home/afernand/SANDBOX/unk_vs_refseq/results

plot_gus_genome.r

library(data.table)
library(tidyverse)
library(ggpubr)
library(ggpubr)

taxonomy <- fread("gzcat ~/Downloads/genomes_taxonomy.tsv.gz", header = FALSE)
unk_vs_rs82 <- fread("gzcat ~/Downloads/gu_vs_refseq82_hypo.tsv.gz", header = FALSE)


unk_vs_rs82_1e25 <- unk_vs_rs82 %>% filter(V11 <= 1e-25) %>% tbl_df %>%
  left_join(taxonomy, by = c("V15" = "V1"))


total_hits <- unk_vs_rs82_1e25$V2.x %>% unique() %>% length()

unk_vs_rs82_1e25_prop <- unk_vs_rs82_1e25 %>% 
  group_by(V2.x, V17) %>% 
  count %>% 
  ungroup() %>%
  group_by(V2.x) %>%
  mutate(prop = n/sum(n)) %>% 
  arrange(V2.x) %>%
  ungroup() %>%
  complete(V2.x, V17, fill = list(prop = 0, n = 0))



unk_vs_rs82_1e25_prop %>%
  gghistogram(x = "prop",
              color = "V17",
              fill = "V17") +
  theme_light()

g_c_gu %>% as.tibble() %>%
  left_join(order_names) %>%
  right_join(hits_hypo_1 %>%
  mutate(cluster_id = as.character(V2.x))) %>%
  .$components %>% table %>% hist

hits_hypo_1 <- unk_vs_rs82_1e25_prop %>%
  filter(V17 == "hypo") %>%
  filter(prop == 1) 

hits_hypo_75_1 <- unk_vs_rs82_1e25_prop %>%
  filter(V17 == "hypo") %>%
  filter(prop >= 0.75) 

hits_hypo_75_99 <- unk_vs_rs82_1e25_prop %>%
  filter(V17 == "hypo") %>%
  filter(prop >= 0.75, prop < 1) 

hits_hypo_50_75 <- unk_vs_rs82_1e25_prop %>%
  filter(V17 == "hypo") %>%
  filter(prop >= 0.5, prop < 0.75) 

hits_hypo_lt50 <- unk_vs_rs82_1e25_prop %>%
  filter(V17 == "hypo") %>%
  filter(prop < 0.5) 

df <- data_frame(cl = c("100%","(100%,75%]","(75%,50%]","(50%,0)"),
                 prop = c(dim(hits_hypo_1)[[1]]/total_hits,
                          dim(hits_hypo_75_99)[[1]]/total_hits,
                          dim(hits_hypo_50_75)[[1]]/total_hits,
                          dim(hits_hypo_lt50)[[1]]/total_hits))

df$cl <- factor(df$cl, levels = rev(c("100%","(100%,75%]","(75%,50%]","(50%,0)")))
ggplot(df, aes(cl, prop)) +
  geom_bar(stat = "identity") +
  rotate() +
  theme_light() +
  ylab("Proportion") +
  xlab("Proportion of hits to hypothetical") +
  scale_y_continuous(labels = scales::percent, limits = c(0,0.80))



hits_hypo$prop %>% summary
hits_hypo_75_99$prop %>% summary
hits_hypo_50_75$prop %>% summary
hits_hypo_lt50$prop %>% summary

hits_hypo$prop %>% length()
hits_hypo_75_99$prop %>% length()
hits_hypo_50_75$prop %>% length()
hits_hypo_lt50$prop %>% length()


unk_vs_rs82_1e25 %>%
  ungroup %>%
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  select(V2.x, V15) %>%
  group_by(V2.x, V15) %>% unique %>% 
  ungroup() %>%
  group_by(V2.x) %>%
  count %>%
  gghistogram(x="n", bins = nclass.Sturges(hits_hypo_1$n), fill = "#3A3A3A") +
  scale_y_sqrt(labels = scales::comma, breaks = scales::trans_breaks("sqrt", function(x) x^2)) +
  scale_x_sqrt(labels = scales::comma, breaks = scales::trans_breaks("sqrt", function(x) x^2)) +
    theme_light() +
  ylab("Number of clusters") +
  xlab("Number of genomes")

l<-unk_vs_rs82_1e25 %>%
  ungroup %>%
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  select(V2.x, V15) %>%
  group_by(V2.x, V15) %>% unique %>% 
  ungroup() %>%
  group_by(V2.x) %>%
  count
  
l1<-l %>% ungroup() %>% top_n(100, wt = n) 

l_phy<-unk_vs_rs82_1e25 %>%
  ungroup %>%
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  select(V2.x, V3.y) %>%
  group_by(V2.x, V3.y) %>% unique %>% 
  ungroup() %>%
  group_by(V2.x) %>%
  count
l_phy %>%
gghistogram(x="n", bins = nclass.Sturges(hits_hypo_1$n), fill = "#3A3A3A") +
   theme_light() +
  ylab("Number of clusters") +
  xlab("Number of genomes")



unk_vs_rs82_1e25 %>% 
  filter(V2.x %in% hits_hypo_1$V2.x) %>%
  group_by(V2.x) %>% count() %>% .$n %>% hist

unk_vs_rs82_1e25 %>% 
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  group_by(V15) %>% count() %>% .$n %>% hist


unk_vs_rs82_1e25 %>% 
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  group_by(V2.y) %>%
  count() %>%
  mutate(V3.y = fct_reorder(V3.y, n)) %>%
  ggplot(aes(V2.y, n)) +
  geom_bar(stat = "identity") +
  theme_light() +
  theme(axis.text.x = element_text(angle = 45, vjust = 1, hjust = 1))


l2 <- unk_vs_rs82_1e25 %>% 
  #filter(V2.x %in% l1$V2.x) %>%
  select(V2.x, V3.y) %>%
  group_by(V3.y) %>%
  unique %>%
  filter(!is.na(V3.y)) %>%
  count() 

l2$V3.y <- factor(l2$V3.y , levels = l2 %>% arrange((n)) %>% .$V3.y)
l2%>%
  ggplot(aes(V3.y, n)) +
  rotate() +
  geom_bar(stat = "identity") +
  theme_light() +
  ylab("Hits") +
  xlab("Phylum") +
  scale_y_continuous(labels = scales::comma)

unk_vs_rs82_1e25 %>% 
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  filter(V3.y == "Actinobacteria") %>%
  select(V2.x, V4.y) %>%
  unique %>%
  group_by(V4.y) %>% count() %>%
  ggplot(aes(V4.y, n)) +
  geom_bar(stat = "identity") +
  theme_light() +
  theme(axis.text.x = element_text(angle = 45, vjust = 1, hjust = 1)) 

unk_vs_rs82_1e25 %>% 
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  filter(V3.y == "Bacteroidetes") %>%
  select(V2.x, V4.y) %>%
  unique %>%
  group_by(V4.y) %>% count() %>%
  ggplot(aes(V4.y, n)) +
  geom_bar(stat = "identity") +
  theme_light() +
  theme(axis.text.x = element_text(angle = 45, vjust = 1, hjust = 1)) 

unk_vs_rs82_1e25 %>% 
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  filter(V3.y == "Firmicutes") %>%
  select(V2.x, V4.y) %>%
  unique %>%
  group_by(V4.y) %>% count() %>%
  ggplot(aes(V4.y, n)) +
  geom_bar(stat = "identity") +
  theme_light() +
  theme(axis.text.x = element_text(angle = 45, vjust = 1, hjust = 1)) 

unk_vs_rs82_1e25 %>% 
  filter(V2.x %in% hits_hypo_75_1$V2.x) %>%
  filter(V3.y == "Proteobacteria") %>%
  select(V2.x, V4.y) %>%
  unique %>%
  group_by(V4.y) %>% count() %>%
  ggplot(aes(V4.y, n)) +
  geom_bar(stat = "identity") +
  theme_light() +
  theme(axis.text.x = element_text(angle = 45, vjust = 1, hjust = 1)) 

rename_headers.sh

#!/bin/bash
NAM=$(basename ${1} _protein.faa.gz)
awk -vN=${NAM} '{if ($0 ~ /^>/){print $0"\t"N}else{print $0}}' <(zcat ${1}) > ${NAM}.faa

unknown_grep.tsv

Uncharacterized
uncharacterized
Hypothetical
hypothetical
Uncaracterized
uncaracterized
Hipothetical
hipothetical
Hypotetical
hypotetical
Hipotetical
hipotetical
Ipotetical
ipotetical
Ipothetical
ipothetical
Uncharacterised
uncharacterised
Uncaracterised
uncaracterised
unknown
DUF
TIGR00011
TIGR00024
TIGR00044
TIGR00092
TIGR00106
TIGR00149
TIGR00153
TIGR00156
TIGR00159
TIGR00161
TIGR00162
TIGR00164
TIGR00186
TIGR00196
TIGR00197
TIGR00245
TIGR00247
TIGR00250
TIGR00251
TIGR00252
TIGR00253
TIGR00255
TIGR00257
TIGR00258
TIGR00264
TIGR00266
TIGR00267
TIGR00268
TIGR00269
TIGR00270
TIGR00282
TIGR00284
TIGR00288
TIGR00289
TIGR00294
TIGR00295
TIGR00296
TIGR00297
TIGR00299
TIGR00300
TIGR00303
TIGR00304
TIGR00311
TIGR00318
TIGR00323
TIGR00340
TIGR00341
TIGR00366
TIGR00367
TIGR00368
TIGR00370
TIGR00375
TIGR00376
TIGR00411
TIGR00412
TIGR00425
TIGR00427
TIGR00454
TIGR00481
TIGR00486
TIGR00488
TIGR00494
TIGR00495
TIGR00529
TIGR00537
TIGR00539
TIGR00540
TIGR00542
TIGR00645
TIGR00646
TIGR00659
TIGR00686
TIGR00688
TIGR00701
TIGR00703
TIGR00704
TIGR00725
TIGR00726
TIGR00730
TIGR00734
TIGR00736
TIGR00789
TIGR01158
TIGR01177
TIGR01209
TIGR01210
TIGR01212
TIGR01244
TIGR01303
TIGR01304
TIGR01334
TIGR01342
TIGR01370
TIGR01407
TIGR01412
TIGR01415
TIGR01437
TIGR01440
TIGR01448
TIGR01454
TIGR01456
TIGR01457
TIGR01458
TIGR01459
TIGR01475
TIGR01490
TIGR01491
TIGR01513
TIGR01542
TIGR01544
TIGR01545
TIGR01548
TIGR01555
TIGR01560
TIGR01561
TIGR01563
TIGR01577
TIGR01578
TIGR01579
TIGR01581
TIGR01616
TIGR01618
TIGR01619
TIGR01620
TIGR01621
TIGR01626
TIGR01630
TIGR01633
TIGR01657
TIGR01666
TIGR01668
TIGR01671
TIGR01672
TIGR01684
TIGR01690
TIGR01701
TIGR01705
TIGR01714
TIGR01721
TIGR01725
TIGR01739
TIGR01777
TIGR01831
TIGR01870
TIGR01878
TIGR01883
TIGR01894
TIGR01896
TIGR01897
TIGR01906
TIGR01949
TIGR01952
TIGR01956
TIGR01976
TIGR01977
TIGR01993
TIGR02003
TIGR02004
TIGR02076
TIGR02099
TIGR02117
TIGR02133
TIGR02146
TIGR02156
TIGR02157
TIGR02158
TIGR02160
TIGR02173
TIGR02178
TIGR02186
TIGR02187
TIGR02190
TIGR02192
TIGR02196
TIGR02200
TIGR02204
TIGR02206
TIGR02215
TIGR02216
TIGR02219
TIGR02220
TIGR02221
TIGR02230
TIGR02234
TIGR02245
TIGR02256
TIGR02291
TIGR02293
TIGR02300
TIGR02301
TIGR02302
TIGR02304
TIGR02327
TIGR02328
TIGR02353
TIGR02358
TIGR02366
TIGR02391
TIGR02396
TIGR02421
TIGR02442
TIGR02443
TIGR02444
TIGR02449
TIGR02450
TIGR02452
TIGR02457
TIGR02458
TIGR02459
TIGR02463
TIGR02485
TIGR02498
TIGR02501
TIGR02526
TIGR02530
TIGR02531
TIGR02535
TIGR02536
TIGR02556
TIGR02569
TIGR02574
TIGR02577
TIGR02578
TIGR02579
TIGR02581
TIGR02584
TIGR02587
TIGR02588
TIGR02591
TIGR02606
TIGR02609
TIGR02610
TIGR02611
TIGR02612
TIGR02613
TIGR02620
TIGR02635
TIGR02642
TIGR02645
TIGR02646
TIGR02647
TIGR02652
TIGR02653
TIGR02668
TIGR02674
TIGR02677
TIGR02678
TIGR02679
TIGR02680
TIGR02682
TIGR02683
TIGR02684
TIGR02687
TIGR02688
TIGR02699
TIGR02700
TIGR02710
TIGR02722
TIGR02740
TIGR02757
TIGR02808
TIGR02811
TIGR02828
TIGR02873
TIGR02921
TIGR02922
TIGR02935
TIGR02943
TIGR02945
TIGR02947
TIGR02949
TIGR02952
TIGR02954
TIGR02959
TIGR02960
TIGR02979
TIGR02988
TIGR03008
TIGR03012
TIGR03014
TIGR03015
TIGR03016
TIGR03017
TIGR03018
TIGR03019
TIGR03021
TIGR03027
TIGR03032
TIGR03054
TIGR03055
TIGR03056
TIGR03073
TIGR03076
TIGR03077
TIGR03084
TIGR03085
TIGR03086
TIGR03087
TIGR03088
TIGR03089
TIGR03097
TIGR03098
TIGR03099
TIGR03100
TIGR03101
TIGR03103
TIGR03104
TIGR03106
TIGR03108
TIGR03109
TIGR03110
TIGR03111
TIGR03112
TIGR03113
TIGR03114
TIGR03115
TIGR03116
TIGR03117
TIGR03118
TIGR03123
TIGR03143
TIGR03151
TIGR03157
TIGR03159
TIGR03165
TIGR03166
TIGR03169
TIGR03202
TIGR03212
TIGR03214
TIGR03223
TIGR03233
TIGR03252
TIGR03266
TIGR03267
TIGR03268
TIGR03270
TIGR03271
TIGR03272
TIGR03274
TIGR03275
TIGR03276
TIGR03277
TIGR03279
TIGR03280
TIGR03281
TIGR03282
TIGR03285
TIGR03286
TIGR03287
TIGR03291
TIGR03308
TIGR03309
TIGR03312
TIGR03313
TIGR03318
TIGR03320
TIGR03329
TIGR03340
TIGR03341
TIGR03347
TIGR03348
TIGR03351
TIGR03352
TIGR03353
TIGR03354
TIGR03355
TIGR03357
TIGR03358
TIGR03359
TIGR03360
TIGR03362
TIGR03363
TIGR03364
TIGR03366
TIGR03368
TIGR03373
TIGR03405
TIGR03406
TIGR03418
TIGR03424
TIGR03425
TIGR03427
TIGR03428
TIGR03432
TIGR03459
TIGR03460
TIGR03466
TIGR03467
TIGR03468
TIGR03469
TIGR03470
TIGR03471
TIGR03472
TIGR03473
TIGR03480
TIGR03481
TIGR03485
TIGR03486
TIGR03487
TIGR03489
TIGR03492
TIGR03503
TIGR03504
TIGR03526
TIGR03527
TIGR03540
TIGR03541
TIGR03543
TIGR03549
TIGR03576
TIGR03577
TIGR03578
TIGR03579
TIGR03580
TIGR03581
TIGR03582
TIGR03583
TIGR03587
TIGR03642
TIGR03643
TIGR03644
TIGR03645
TIGR03667
TIGR03668
TIGR03693
TIGR03709
TIGR03728
TIGR03734
TIGR03735
TIGR03736
TIGR03737
TIGR03738
TIGR03739
TIGR03745
TIGR03746
TIGR03747
TIGR03748
TIGR03749
TIGR03750
TIGR03751
TIGR03752
TIGR03756
TIGR03757
TIGR03758
TIGR03759
TIGR03761
TIGR03764
TIGR03766
TIGR03767
TIGR03768
TIGR03773
TIGR03789
TIGR03792
TIGR03805
TIGR03806
TIGR03809
TIGR03813
TIGR03815
TIGR03816
TIGR03817
TIGR03819
TIGR03822
TIGR03826
TIGR03829
TIGR03833
TIGR03842
TIGR03843
TIGR03850
TIGR03853
TIGR03854
TIGR03857
TIGR03858
TIGR03864
TIGR03868
TIGR03869
TIGR03873
TIGR03875
TIGR03876
TIGR03877
TIGR03878
TIGR03880
TIGR03881
TIGR03885
TIGR03886
TIGR03890
TIGR03894
TIGR03899
TIGR03900
TIGR03903
TIGR03904
TIGR03905
TIGR03913
TIGR03914
TIGR03916
TIGR03931
TIGR03936
TIGR03941
TIGR03943
TIGR03950
TIGR03959
TIGR03960
TIGR03961
TIGR03964
TIGR03965
TIGR03966
TIGR03967
TIGR03968
TIGR03970
TIGR03973
TIGR03974
TIGR03976
TIGR03977
TIGR03978
TIGR03979
TIGR03981
TIGR03982
TIGR03984
TIGR03985
TIGR03986
TIGR03987
TIGR03991
TIGR03995
TIGR03996
TIGR03997
TIGR04002
TIGR04013
TIGR04014
TIGR04018
TIGR04019
TIGR04024
TIGR04027
TIGR04028
TIGR04029
TIGR04030
TIGR04039
TIGR04040
TIGR04041
TIGR04042
TIGR04043
TIGR04044
TIGR04045
TIGR04046
TIGR04047
TIGR04049
TIGR04050
TIGR04052
TIGR04062
TIGR04063
TIGR04065
TIGR04066
TIGR04069
TIGR04072
TIGR04082
TIGR04083
TIGR04086
TIGR04097
TIGR04099
TIGR04100
TIGR04101
TIGR04102
TIGR04108
TIGR04111
TIGR04112
TIGR04113
TIGR04116
TIGR04123
TIGR04124
TIGR04127
TIGR04129
TIGR04132
TIGR04133
TIGR04134
TIGR04136
TIGR04137
TIGR04138
TIGR04142
TIGR04145
TIGR04156
TIGR04161
TIGR04165
TIGR04168
TIGR04169
TIGR04172
TIGR04175
TIGR04177
TIGR04179
TIGR04180
TIGR04181
TIGR04190
TIGR04205
TIGR04206
TIGR04211
TIGR04212
TIGR04220
TIGR04229
TIGR04249
TIGR04252
TIGR04260
TIGR04268
TIGR04276
TIGR04280
TIGR04281
TIGR04282
TIGR04283
TIGR04284
TIGR04290
TIGR04292
TIGR04293
TIGR04295
TIGR04297
TIGR04302
TIGR04303
TIGR04304
TIGR04318
TIGR04335
TIGR04336
TIGR04337
TIGR04338
TIGR04339
TIGR04340
TIGR04348
TIGR04349
TIGR04352
TIGR04355
TIGR04356
TIGR04357
TIGR04360
TIGR04369
TIGR04374
TIGR04375
TIGR04376
TIGR04385
TIGR04400
TIGR04413
TIGR04420
TIGR04421
TIGR04422
TIGR04423
TIGR04434
TIGR04435
TIGR04438
TIGR04442
TIGR04454
TIGR04455
TIGR04470
TIGR04471
TIGR04472
TIGR04477
TIGR04503
TIGR04522
TIGR04533
TIGR04535
TIGR04536
TIGR04540
TIGR04542
TIGR04548
TIGR04553
TIGR04554
TIGR04558
TIGR04559
TIGR04561
TIGR04570
PF08975
PF03752
PF09713
PF17623
PF13754
PF17615
PF01930
PF14916
PF09717
PF01982
PF05899
PF17074
PF06207
PF06210
PF06219
PF06226
PF06230
PF06231
PF06237
PF06242
PF06245
PF06250
PF06252
PF06260
PF06265
PF06267
PF06269
PF06270
PF06275
PF06279
PF06281
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PF06287
PF01954
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PF06304
PF06327
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PF06417
PF06435
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PF06454
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PF06469
PF06476
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PF06485
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PF06493
PF06496
PF06497
PF01345
PF06500
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PF06513
PF06518
PF06523
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PF01969
PF06533
PF06544
PF06545
PF06547
PF06549
PF06551
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PF06563
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PF06592
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PF06620
PF06625
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PF06721
PF06722
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PF06727
PF06736
PF06740
PF06742
PF06746
PF06748
PF06749
PF06758
PF06760
PF06764
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PF01986
PF06799
PF06802
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PF06822
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PF06836
PF06840
PF06842
PF06844
PF06849
PF06851
PF06852
PF06853
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PF06863
PF06865
PF06866
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PF06869
PF01989
PF06880
PF06882
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PF06887
PF06889
PF06897
PF06900
PF06906
PF06908
PF06912
PF06916
PF01995
PF06918
PF06924
PF06930
PF06932
PF06935
PF06938
PF06939
PF06940
PF06945
PF06947
PF06949
PF06950
PF06961
PF06966
PF06972
PF06973
PF06974
PF06975
PF06980
PF06993
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PF07000
PF01998
PF07006
PF07011
PF07013
PF07023
PF07026
PF07027
PF07028
PF07030
PF07032
PF07038
PF07040
PF07041
PF07043
PF07044
PF07045
PF07048
PF07056
PF07059
PF07063
PF02001
PF07067
PF07075
PF07076
PF07077
PF07079
PF07080
PF07081
PF07082
PF07083
PF07087
PF07092
PF07094
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PF07097
PF07098
PF07099
PF07101
PF07102
PF07103
PF07104
PF07105
PF07112
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PF07118
PF07119
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PF07125
PF07128
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PF07131
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PF07136
PF07138
PF07139
PF07142
PF07146
PF07150
PF07151
PF07154
PF07159
PF07165
PF07166
PF07176
PF07182
PF07183
PF07185
PF07187
PF07190
PF07193
PF07197
PF07198
PF07199
PF07203
PF07205
PF07208
PF07209
PF07210
PF07214
PF07215
PF07220
PF07226
PF07233
PF07235
PF07237
PF07242
PF07248
PF07252
PF07256
PF07270
PF07273
PF07274
PF07278
PF07279
PF07285
PF07286
PF07288
PF07290
PF07293
PF07301
PF07305
PF07306
PF07308
PF07312
PF07313
PF07314
PF07315
PF07316
PF07318
PF07323
PF07326
PF07330
PF07338
PF07339
PF07341
PF07342
PF07343
PF07345
PF07346
PF07349
PF07350
PF02520
PF07351
PF07356
PF07358
PF07363
PF07368
PF07369
PF07370
PF07371
PF07372
PF07374
PF07377
PF07379
PF07383
PF07384
PF07386
PF07389
PF07394
PF07397
PF07403
PF07405
PF07408
PF07411
PF07420
PF07423
PF07431
PF07433
PF07438
PF07439
PF07457
PF07466
PF07469
PF07481
PF07482
PF07509
PF07510
PF07511
PF07485
PF07550
PF07551
PF07556
PF07560
PF07561
PF07563
PF07564
PF07566
PF07577
PF07579
PF07588
PF07590
PF07597
PF07598
PF07599
PF07600
PF07602
PF07603
PF07606
PF07607
PF07608
PF07609
PF07610
PF07611
PF07613
PF07614
PF07617
PF07618
PF07619
PF07621
PF07622
PF07625
PF07628
PF07629
PF07632
PF07643
PF07659
PF01519
PF07667
PF07671
PF07713
PF07753
PF07754
PF07755
PF17396
PF07756
PF07758
PF07759
PF07760
PF07761
PF07762
PF07773
PF07774
PF07784
PF07785
PF07786
PF07789
PF07791
PF07793
PF07794
PF07843
PF07795
PF07845
PF07796
PF07797
PF07798
PF07849
PF07852
PF07799
PF07800
PF07816
PF07854
PF07801
PF07853
PF07864
PF07865
PF07866
PF07867
PF07868
PF07869
PF07870
PF07871
PF07872
PF02593
PF07877
PF07909
PF07889
PF07891
PF07892
PF07893
PF07894
PF07900
PF07901
PF07895
PF07896
PF07898
PF07911
PF07913
PF07914
PF07933
PF07946
PF07920
PF07939
PF07937
PF07955
PF07958
PF07954
PF07956
PF07950
PF07997
PF08002
PF08004
PF08006
PF08012
PF08014
PF08019
PF08020
PF08044
PF08101
PF08217
PF08213
PF05414
PF08224
PF08226
PF08349
PF08350
PF08333
PF08351
PF08353
PF08354
PF08331
PF08338
PF08340
PF08522
PF08409
PF08410
PF08401
PF08427
PF08489
PF08490
PF08508
PF08520
PF08538
PF08550
PF08555
PF08560
PF03564
PF08570
PF08576
PF08578
PF08719
PF08588
PF08589
PF08590
PF08592
PF08593
PF08611
PF08643
PF08648
PF08681
PF08682
PF08747
PF08760
PF08768
PF08796
PF08807
PF08811
PF08818
PF08819
PF08820
PF08822
PF08827
PF08830
PF08837
PF08838
PF08844
PF08846
PF08848
PF08850
PF08852
PF08853
PF08854
PF08855
PF08856
PF08860
PF08861
PF08862
PF08865
PF08875
PF08873
PF08874
PF08876
PF08878
PF08894
PF08893
PF08895
PF08897
PF08896
PF08898
PF08899
PF08900
PF08903
PF08901
PF08902
PF08904
PF08905
PF08906
PF08908
PF08907
PF08909
PF08983
PF08982
PF08984
PF08948
PF08949
PF08950
PF08933
PF08952
PF08956
PF08965
PF08958
PF08960
PF08962
PF08974
PF08963
PF08966
PF08980
PF08967
PF08968
PF09002
PF08986
PF09001
PF09004
PF08987
PF08979
PF08989
PF09005
PF08953
PF01579
PF08972
PF08921
PF08922
PF08924
PF08925
PF08926
PF08928
PF08929
PF08930
PF08939
PF08940
PF08942
PF09081
PF09082
PF09083
PF09086
PF09094
PF09095
PF09118
PF09122
PF09123
PF09130
PF09147
PF09148
PF09149
PF09151
PF09152
PF09153
PF09154
PF09155
PF09167
PF09172
PF09175
PF09178
PF09183
PF09185
PF09186
PF09188
PF09189
PF09196
PF09205
PF09209
PF09210
PF09211
PF09218
PF09224
PF09227
PF09234
PF09244
PF09248
PF09260
PF09269
PF09291
PF09301
PF09313
PF09314
PF09317
PF09320
PF09321
PF09322
PF09323
PF09324
PF09327
PF09331
PF09342
PF09345
PF09347
PF09348
PF09350
PF09351
PF09353
PF09362
PF09366
PF09369
PF09390
PF09391
PF09400
PF09404
PF09406
PF09418
PF09428
PF09430
PF09431
PF09427
PF09435
PF09436
PF09438
PF09442
PF09450
PF02656
PF09449
PF09633
PF09630
PF09634
PF09641
PF09640
PF09667
PF09592
PF10356
PF09861
PF09862
PF01595
PF09935
PF09940
PF09951
PF01629
PF02713
PF09970
PF02720
PF02721
PF02890
PF10038
PF02989
PF10047
PF10049
PF10052
PF02995
PF03008
PF10102
PF09823
PF10176
PF09574
PF09558
PF09536
PF09543
PF09533
PF09544
PF09557
PF09537
PF09722
PF09539
PF09498
PF09523
PF09624
PF09654
PF09660
PF09661
PF09664
PF09674
PF10293
PF10303
PF03087
PF10329
PF10332
PF10336
PF10338
PF10348
PF03103
PF10353
PF10354
PF10360
PF10361
PF10365
PF10370
PF10382
PF10386
PF10387
PF10398
PF10476
PF10474
PF10504
PF10445
PF10446
PF10454
PF09601
PF09495
PF09591
PF10239
PF10611
PF03140
PF10615
PF10616
PF10617
PF10629
PF10630
PF10631
PF10649
PF10651
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PF10654
PF10655
PF10656
PF10658
PF10667
PF10673
PF10675
PF10677
PF10679
PF10678
PF10686
PF10689
PF10691
PF10692
PF10693
PF10694
PF10696
PF10697
PF10698
PF10702
PF10704
PF10713
PF10708
PF10709
PF10710
PF10721
PF10720
PF10724
PF10725
PF10728
PF10730
PF10734
PF10732
PF10733
PF10735
PF10736
PF10800
PF10740
PF10745
PF10748
PF10811
PF10752
PF10749
PF10751
PF10750
PF10801
PF10804
PF10802
PF10807
PF10808
PF10820
PF11245
PF10810
PF10818
PF10739
PF10826
PF10827
PF10830
PF10829
PF10742
PF10831
PF10832
PF10834
PF10812
PF10817
PF10819
PF10821
PF10823
PF10754
PF03192
PF10828
PF10833
PF10835
PF10836
PF10837
PF10845
PF10844
PF10762
PF10763
PF10755
PF10758
PF10759
PF11655
PF10761
PF10765
PF10767
PF10769
PF10772
PF10783
PF10776
PF10788
PF10790
PF10792
PF10794
PF10795
PF11019
PF03196
PF11020
PF11022
PF11041
PF11021
PF11027
PF11077
PF10936
PF10940
PF10942
PF03235
PF10941
PF11084
PF11115
PF11116
PF10946
PF11117
PF11118
PF10947
PF10944
PF10939
PF10943
PF11119
PF10934
PF10948
PF10935
PF11121
PF10842
PF10841
PF10840
PF10839
PF10855
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PF10852
PF10851
PF10850
PF10849
PF10848
PF10847
PF10858
PF10859
PF10860
PF10864
PF10867
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PF03268
PF10875
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PF10878
PF10880
PF10879
PF11247
PF10838
PF10856
PF03269
PF10925
PF10883
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PF10885
PF10886
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PF10892
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PF03270
PF10901
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PF10912
PF10857
PF10865
PF10866
PF10920
PF10913
PF10915
PF10921
PF10924
PF10916
PF10897
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PF10895
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PF10911
PF10918
PF10891
PF03312
PF11026
PF10846
PF11028
PF10893
PF10881
PF10870
PF03314
PF10805
PF10809
PF10813
PF10931
PF10930
PF10927
PF10872
PF10888
PF10910
PF10922
PF10874
PF10871
PF10907
PF11042
PF10825
PF10952
PF10953
PF10954
PF10956
PF10955
PF10958
PF10816
PF10959
PF10962
PF10964
PF10965
PF10966
PF10967
PF10968
PF10969
PF10971
PF11242
PF10951
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PF10908
PF11074
PF11075
PF10914
PF11191
PF10932
PF10861
PF10978
PF10979
PF10980
PF10981
PF10982
PF10976
PF10923
PF10983
PF10984
PF11387
PF10986
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PF11391
PF10973
PF10926
PF10975
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PF10985
PF10987
PF10989
PF10990
PF03436
PF10928
PF10929
PF11193
PF11398
PF10991
PF10992
PF10994
PF10993
PF03380
PF11039
PF11442
PF10933
PF11443
PF11195
PF11125
PF11090
PF11196
PF11197
PF10998
PF10999
PF11000
PF11001
PF11003
PF11005
PF11006
PF11008
PF11009
PF11010
PF11011
PF03382
PF11012
PF11013
PF11014
PF11015
PF11016
PF11017
PF11043
PF11198
PF11072
PF11059
PF11060
PF11061
PF11062
PF11064
PF11065
PF11066
PF11067
PF03384
PF11069
PF11070
PF11395
PF11394
PF11392
PF11086
PF11082
PF11097
PF11101
PF11103
PF11135
PF11136
PF11081
PF11199
PF11127
PF11445
PF11444
PF11446
PF01724
PF11146
PF11137
PF11138
PF11140
PF11141
PF11142
PF11143
PF11144
PF11145
PF11148
PF11149
PF11150
PF11151
PF11153
PF11666
PF11154
PF11155
PF11157
PF11158
PF11159
PF11161
PF11160
PF11162
PF11163
PF11164
PF11165
PF03478
PF11453
PF11166
PF11167
PF11168
PF11169
PF11170
PF11171
PF11172
PF03479
PF11173
PF11175
PF11178
PF11177
PF11179
PF11180
PF11184
PF11174
PF11185
PF11186
PF11189
PF11187
PF11188
PF11190
PF11192
PF11200
PF11201
PF11204
PF11661
PF11205
PF11207
PF11693
PF11208
PF11209
PF11210
PF11211
PF11212
PF11452
PF11448
PF11213
PF11460
PF11215
PF11218
PF11216
PF11217
PF11219
PF11220
PF11454
PF11222
PF11455
PF11456
PF03625
PF11223
PF11457
PF11226
PF11224
PF11225
PF11227
PF11228
PF11230
PF11231
PF11233
PF11236
PF11237
PF11238
PF11239
PF11240
PF11241
PF11243
PF11248
PF11249
PF11258
PF17479
PF03713
PF11251
PF11252
PF11253
PF11254
PF11255
PF11256
PF11259
PF11267
PF11271
PF11269
PF11270
PF11268
PF11272
PF11273
PF11274
PF11275
PF11276
PF11278
PF03729
PF11279
PF11280
PF11282
PF11281
PF11283
PF11284
PF11285
PF11286
PF11287
PF11288
PF03745
PF11290
PF11291
PF11292
PF11293
PF11294
PF11295
PF11296
PF11297
PF11298
PF11299
PF11300
PF11301
PF11302
PF11303
PF11304
PF11305
PF11306
PF11307
PF11360
PF11309
PF11310
PF11311
PF11313
PF11314
PF11317
PF11318
PF11320
PF11321
PF11322
PF11323
PF11324
PF11325
PF11326
PF11327
PF03754
PF11328
PF11329
PF11330
PF11332
PF11333
PF11334
PF11335
PF11336
PF11337
PF11338
PF11339
PF11340
PF11341
PF11342
PF11343
PF11344
PF11345
PF11347
PF11346
PF11348
PF11349
PF11350
PF11353
PF11352
PF11354
PF11355
PF11358
PF11361
PF11369
PF11362
PF11363
PF11364
PF11367
PF11368
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PF11992
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PF12001
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PF12345
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PF04123
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PF04028
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PF12562
PF12565
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PF12570
PF12572
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PF12587
PF12591
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PF12600
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PF12616
PF12618
PF12620
PF04070
PF12635
PF12636
PF12644
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PF12650
PF12653
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PF12655
PF12663
PF12664
PF12668
PF12670
PF12672
PF12673
PF12675
PF12676
PF12677
PF12683
PF12684
PF12686
PF12687
PF12290
PF12707
PF12712
PF12713
PF12720
PF10300
PF12723
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PF12758
PF12823
PF12825
PF12842
PF04037
PF12863
PF12864
PF12866
PF12873
PF12875
PF12877
PF12883
PF12889
PF04063
PF12903
PF12915
PF12916
PF12927
PF12930
PF12939
PF12943
PF04064
PF12952
PF12953
PF12954
PF12955
PF12956
PF12957
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PF12959
PF12960
PF12961
PF12962
PF12963
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PF12965
PF12967
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PF12969
PF12970
PF12975
PF04074
PF12976
PF12977
PF12978
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PF12980
PF12981
PF12982
PF12983
PF12984
PF12985
PF12986
PF12987
PF12988
PF12989
PF12990
PF12991
PF12992
PF12993
PF12994
PF12995
PF12997
PF13020
PF13024
PF13021
PF13025
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PF13027
PF13028
PF04087
PF13029
PF13030
PF13031
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PF13033
PF13034
PF13035
PF13037
PF13038
PF04094
PF13039
PF13042
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PF13077
PF13049
PF13050
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PF13052
PF13053
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PF13079
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PF13060
PF13059
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PF13063
PF13080
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PF13066
PF04134
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PF13082
PF13068
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PF13070
PF13071
PF13072
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PF13075
PF13081
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PF13099
PF13101
PF13135
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PF13132
PF13131
PF13130
PF13129
PF13128
PF13127
PF13104
PF13125
PF13105
PF13142
PF13106
PF13111
PF13124
PF13107
PF13112
PF13110
PF13152
PF13108
PF04149
PF13113
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PF13118
PF13119
PF13120
PF13126
PF13121
PF13122
PF13123
PF13141
PF13140
PF13139
PF13138
PF13137
PF13136
PF13153
PF13143
PF13148
PF13150
PF13151
PF13154
PF13157
PF13158
PF13159
PF13160
PF13161
PF13162
PF13163
PF13170
PF13171
PF13178
PF13179
PF13182
PF04165
PF13194
PF13195
PF13196
PF13197
PF13198
PF13209
PF13210
PF13211
PF04167
PF13212
PF13213
PF13214
PF13215
PF13216
PF13217
PF13218
PF13219
PF13220
PF13221
PF13222
PF13223
PF13224
PF13225
PF13226
PF13227
PF13228
PF13204
PF13244
PF13250
PF13251
PF13252
PF13253
PF13254
PF13255
PF13256
PF13257
PF13258
PF13259
PF13260
PF13261
PF13262
PF13264
PF13265
PF13266
PF13267
PF13268
PF04175
PF13269
PF13270
PF13271
PF13273
PF13274
PF13282
PF13281
PF13284
PF13285
PF13293
PF13294
PF13295
PF13300
PF13301
PF13311
PF13312
PF13313
PF13314
PF13321
PF13315
PF13316
PF13317
PF13318
PF13319
PF13320
PF13322
PF13331
PF13334
PF13351
PF04190
PF13352
PF13355
PF13387
PF13388
PF13389
PF13390
PF04214
PF13422
PF13427
PF13430
PF13438
PF13448
PF13464
PF13475
PF13493
PF13494
PF04217
PF13496
PF13497
PF13498
PF13503
PF13511
PF13526
PF13548
PF13552
PF13554
PF13559
PF04219
PF13566
PF13567
PF13569
PF13571
PF13572
PF13575
PF13590
PF13595
PF13598
PF13600
PF13605
PF13628
PF13635
PF13642
PF13643
PF13660
PF13663
PF13664
PF13665
PF13680
PF13687
PF13689
PF13698
PF13699
PF13700
PF13709
PF04222
PF13711
PF13732
PF13739
PF13747
PF13752
PF13761
PF13763
PF13767
PF13770
PF04224
PF13773
PF13775
PF13776
PF13777
PF13778
PF13779
PF13780
PF13783
PF13785
PF13786
PF04235
PF13788
PF13789
PF13799
PF13803
PF13810
PF13811
PF13821
PF13826
PF13827
PF13828
PF13829
PF13830
PF13834
PF13835
PF13836
PF13846
PF13852
PF10670
PF13858
PF04238
PF13863
PF13870
PF13875
PF13886
PF13898
PF13904
PF13907
PF13910
PF04239
PF13915
PF13926
PF13937
PF13946
PF13948
PF13952
PF13959
PF13960
PF13961
PF13968
PF13970
PF13973
PF13978
PF13986
PF13988
PF10774
PF14004
PF14009
PF14012
PF04241
PF14014
PF14015
PF14016
PF14017
PF14018
PF14019
PF14020
PF14022
PF14023
PF04242
PF14024
PF14025
PF14026
PF14027
PF14029
PF14030
PF14033
PF14042
PF14053
PF14054
PF14056
PF14059
PF14060
PF14062
PF14063
PF14065
PF14066
PF14074
PF14076
PF14078
PF14079
PF14080
PF14081
PF14082
PF14084
PF14085
PF14086
PF14087
PF14088
PF14091
PF14092
PF14093
PF14094
PF14096
PF14101
PF14103
PF14104
PF14105
PF14106
PF14107
PF14108
PF14110
PF14111
PF14114
PF14117
PF14119
PF04250
PF14123
PF14124
PF14125
PF14126
PF14127
PF14128
PF14129
PF14130
PF14131
PF14132
PF01861
PF14133
PF14134
PF14135
PF14136
PF14137
PF14146
PF14154
PF14155
PF14172
PF14187
PF14188
PF14189
PF14190
PF14192
PF14193
PF14195
PF14199
PF14201
PF04254
PF14208
PF14209
PF14210
PF14213
PF14216
PF14217
PF14219
PF14220
PF04255
PF14221
PF14224
PF14229
PF14230
PF14232
PF14233
PF14234
PF14235
PF14236
PF14237
PF04256
PF14238
PF14242
PF14243
PF14248
PF14251
PF14252
PF14254
PF14257
PF14258
PF14261
PF11611
PF14263
PF14265
PF14267
PF14270
PF14271
PF04260
PF14273
PF14274
PF14275
PF14276
PF14277
PF14280
PF14283
PF14285
PF14287
PF14289
PF14290
PF14291
PF14294
PF14297
PF14298
PF14300
PF14301
PF14302
PF14309
PF04282
PF14315
PF14316
PF14321
PF14325
PF14326
PF14328
PF14329
PF14330
PF14332
PF14333
PF14334
PF14335
PF14336
PF14337
PF14339
PF14340
PF14342
PF14344
PF14346
PF14347
PF04269
PF14348
PF14351
PF14352
PF14356
PF14357
PF14358
PF14359
PF14362
PF14364
PF04284
PF14366
PF14367
PF14371
PF14372
PF14377
PF14385
PF14386
PF14387
PF14388
PF14391
PF14393
PF14394
PF14415
PF14467
PF14468
PF14471
PF14472
PF04276
PF14478
PF14485
PF14486
PF14487
PF14488
PF14491
PF14494
PF14499
PF14505
PF14530
PF04285
PF14534
PF14536
PF14539
PF14544
PF14563
PF14574
PF14584
PF14590
PF14610
PF14613
PF04286
PF14614
PF14616
PF14618
PF14627
PF14628
PF14643
PF14644
PF14652
PF14660
PF14673
PF14687
PF14688
PF14692
PF14713
PF14717
PF14725
PF14729
PF14730
PF14734
PF04289
PF14737
PF14740
PF14739
PF14747
PF14751
PF14771
PF14780
PF14793
PF14794
PF04296
PF14800
PF14818
PF14825
PF14831
PF14846
PF14858
PF14868
PF14869
PF14879
PF14892
PF14898
PF14899
PF14900
PF14902
PF14906
PF14908
PF14924
PF14926
PF14934
PF01863
PF14937
PF14946
PF14950
PF14951
PF14953
PF14956
PF14958
PF14964
PF14969
PF14970
PF14971
PF14975
PF14983
PF14986
PF14988
PF14990
PF15006
PF15008
PF15012
PF04301
PF15016
PF15021
PF15022
PF15023
PF15025
PF15027
PF15030
PF15031
PF15032
PF15039
PF15041
PF15046
PF15047
PF15049
PF15054
PF15055
PF15057
PF15061
PF15072
PF04304
PF15073
PF15074
PF15075
PF15076
PF15078
PF15080
PF15081
PF15082
PF04305
PF15084
PF15087
PF15089
PF15090
PF15091
PF15093
PF15094
PF15104
PF15112
PF04306
PF15118
PF15123
PF15169
PF15130
PF15131
PF15132
PF15133
PF15134
PF15137
PF15139
PF15140
PF15141
PF15143
PF15144
PF15145
PF15147
PF15158
PF15162
PF15167
PF15223
PF15232
PF15239
PF15248
PF15251
PF15252
PF04311
PF15257
PF15261
PF15262
PF15266
PF15283
PF15363
PF15366
PF15370
PF15371
PF04312
PF15372
PF15373
PF15375
PF15376
PF15377
PF15378
PF15379
PF15380
PF15382
PF15387
PF15389
PF15391
PF15393
PF15394
PF15395
PF15397
PF15398
PF15399
PF15414
PF15416
PF15417
PF15418
PF15425
PF15429
PF15442
PF15443
PF15451
PF15464
PF15465
PF15466
PF15468
PF15470
PF15472
PF15479
PF15480
PF15483
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PF15485
PF15486
PF15488
PF15496
PF15504
PF15505
PF15507
PF04325
PF15509
PF15513
PF15525
PF15546
PF15547
PF15548
PF15551
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PF15555
PF15558
PF15559
PF15576
PF15578
PF15668
PF15679
PF15697
PF15700
PF15701
PF15709
PF15710
PF15716
PF15719
PF15720
PF15726
PF15727
PF15728
PF04318
PF15730
PF15732
PF15733
PF15735
PF15736
PF15737
PF15742
PF15747
PF15752
PF15755
PF04320
PF15756
PF15762
PF15763
PF15764
PF15765
PF15766
PF15767
PF15769
PF15770
PF15773
PF15774
PF15775
PF15787
PF15788
PF15797
PF15806
PF15813
PF15821
PF15828
PF15829
PF15830
PF15831
PF15833
PF15835
PF15837
PF15838
PF15842
PF15843
PF15846
PF15848
PF15849
PF15851
PF15852
PF15854
PF15855
PF15856
PF15860
PF15866
PF04322
PF15873
PF15875
PF15876
PF15878
PF15881
PF15882
PF15883
PF15889
PF15893
PF15897
PF15916
PF15918
PF15923
PF15928
PF15931
PF15932
PF15936
PF04332
PF15938
PF15942
PF15944
PF15945
PF15946
PF15947
PF15948
PF15949
PF15956
PF15958
PF15959
PF15960
PF15961
PF15962
PF15973
PF15983
PF15989
PF15992
PF15994
PF15995
PF15997
PF15998
PF15999
PF16001
PF16003
PF16007
PF16008
PF16009
PF04334
PF16012
PF16013
PF16016
PF16022
PF16023
PF16024
PF16027
PF16029
PF16032
PF16033
PF16037
PF16039
PF16040
PF16041
PF16042
PF16043
PF16044
PF16051
PF16055
PF16056
PF04337
PF16057
PF16059
PF16060
PF16061
PF16062
PF16063
PF16064
PF16065
PF16066
PF16067
PF04338
PF16068
PF16069
PF16071
PF16072
PF16075
PF16086
PF16087
PF16089
PF16090
PF16091
PF16092
PF16103
PF16105
PF16106
PF16107
PF16108
PF16109
PF16110
PF16111
PF04467
PF16112
PF16115
PF16116
PF16117
PF16118
PF16119
PF16120
PF16125
PF16126
PF16127
PF04340
PF16128
PF16129
PF16130
PF16132
PF16133
PF16137
PF16138
PF16139
PF16140
PF04341
PF16142
PF16143
PF16144
PF16145
PF16146
PF16147
PF16148
PF16149
PF16150
PF16151
PF16152
PF16153
PF16154
PF16155
PF16156
PF16157
PF16160
PF16161
PF16162
PF16163
PF09685
PF16167
PF16169
PF16170
PF16173
PF16175
PF16215
PF12870
PF16219
PF04343
PF16220
PF16222
PF16223
PF16224
PF16225
PF16226
PF16227
PF16228
PF16229
PF16230
PF04356
PF16231
PF16232
PF16234
PF16233
PF16235
PF16236
PF16237
PF16238
PF16239
PF16240
PF16241
PF16244
PF16245
PF16246
PF16247
PF16248
PF16249
PF16250
PF16252
PF16253
PF16254
PF16256
PF16258
PF16259
PF16260
PF16261
PF16262
PF16263
PF16265
PF16266
PF16267
PF16268
PF16269
PF16270
PF16271
PF16272
PF16277
PF16279
PF16280
PF16283
PF04359
PF16284
PF16285
PF16286
PF16287
PF16288
PF16289
PF16290
PF16291
PF16292
PF16297
PF04361
PF16298
PF16299
PF13708
PF16301
PF16302
PF16303
PF16304
PF16305
PF16306
PF16307
PF16308
PF16309
PF16310
PF16314
PF16315
PF16316
PF16318
PF16319
PF16323
PF04363
PF16324
PF16328
PF16332
PF16334
PF16335
PF16338
PF16339
PF16341
PF16342
PF16343
PF16344
PF16346
PF16347
PF16349
PF16351
PF04430
PF16352
PF16353
PF16355
PF16356
PF16372
PF16373
PF16375
PF16377
PF16378
PF16379
PF04465
PF16380
PF16383
PF16384
PF16385
PF16386
PF16387
PF16389
PF16390
PF16391
PF16392
PF16394
PF16395
PF16396
PF16397
PF16398
PF16400
PF16401
PF04417
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