__init__.py

from . import views

def main(global_config, **settings):
    #trimmed for length
    config.add_route('home', '/')
    config.add_view(views.AngularWrapper(views.home), route_name='home', xhr=False, renderer='index.mako')
    config.add_view(views.home, route_name='home', xhr=True, renderer='json')
    return config.make_wsgi_app()

views.py

def prepare_preload(request, view_callable):
    preload_data = view_callable(request)
    flash = request.session.pop_flash()
    return {'preload': preload_data, 'flash': flash}

class AngularWrapper(object):
    __slots__ = ['view_callable']
    def __init__(self, view_callable):
        self.view_callable = view_callable
    def __call__(self, request):
        return prepare_preload(request, self.view_callable)

def home(request):
    return {}