Do like Facebook/Twitter

truph_photo.js

TRUPH = jQuery.extend(true, TRUPH||{}, {
  domain: "http://tru.ph",
  basePath: "/photo",
  getBaseUrl: function(){
    return TRUPH.domain+TRUPH.basePath;
  },
  shebang: "#!"
});

jQuery(function($){
  
  $("a").removeAttr("onclick") // no more onclick
    // replace href with AJAXified ver
    .attr("href", function(){
      return this.href.replace(TRUPH.getBaseUrl(), TRUPH.shebang);
    });
    
  // use onhashchange if available
  if ("onhashchange" in window) {
    window.onhashchange = function(){
      // todo update menu
      // update display
      $("#display").load(TRUPH.basePath+location.hash.replace(TRUPH.shebang, ""));
    };
  }
  // use onclick
  else {
    $("a").live("click", function(e){
      // todo update menu
      // update display
      $("#display").load(TRUPH.basePath+this.href.replace(TRUPH.shebang), "");
    });
  }
});