thing.py

from sqlalchemy import and_, or_, not_

q = select([tblthing.c.id, tblthing.c.zip, tblthing.c.structure])

conditions = or_()

for row in df.iterrows():
  conditions.append(and_(tblthing.c.id=row['id'], tblthing.c.zip=row['zip']))

q = q.where(conditions)
for row in connection.execute(q):
    print(row)