SMARTSPattern.java

IChemObjectBuilder bldr  = SilentChemObjectBuilder.getInstance();
SmilesParser       smipar = new SmilesParser(bldr);

Pattern ptrn = SmartsPattern.create("O=[C,N]aa[N,O;!H0]", null);

try (Reader         frdr = new FileReader(fname);
     BufferedReader brdr = new BufferedReader(frdr)) {
    
    String line;
    
    while ((line = brdr.readLine()) != null)
        if (ptrn.matches(smipar.parseSmiles(line)))
            System.out.println(line);
}