The Isle Game.ini

Game.ini

[/script/theisle.igamesession]
ServerName=xxx
ServerPassword=
ServerSteamGroup=
ServerMOTD=Hi There :3
bFamilySharing=false
bServerDatabase=true
bServerAllowChat=true
bServerGlobalChat=true
bServerNameTags=true
bServerExperimental=false
bServerBattleye=true
bServerAI=true
ServerAIMax=100
ServerAIRate=50.0
bServerAIPlayerSpawns=true
bServerGrowth=false
bServerNesting=true
bServerScent=false
bServerAllowTurnInPlace=true
ServerDeadBodyTime=0
ServerRespawnTime=10
ServerLogoutTime=10
; Discord Invite link eg ServerDiscord=0lGZKDGlkAu0fHGl
ServerDiscord=xxx
ServerAdmins=123
ServerAdmins=456

[/script/theisle.igamemode]
; Dinosaur Overrides
;ProgressionOverrides=(Row="Austro",Points=10)
;ProgressionOverrides=(Row="TRex",Points=20)

; Time of Day / Weather Settings
ServerStartingTime=1350
bServerDynamicTimeOfDay=0
ServerDayLength=20

; Supported Database Types: (None, SQLite, MariaDB)
;DatabaseType=SQLite
;DatabaseHost=127.0.0.127
;DatabasePort=3306
;DatabaseUser=root
;DatabasePass=

bServerDatabase=true [/script/theisle.igamemode] DatabaseType=MariaDB DatabaseHost=127.0.0.1 DatabasePort=3306 DatabaseUser=root DatabasePass=psswd

After setting it up like this, I will still use the local file

Depricated feature, only supports local database json files - as you have already. Likewise you cannot adjust AI settings besides turning them on and off.