local_appdata.py

import ctypes
from ctypes import wintypes, windll

CSIDL_LOCAL_APPDATA = 28

_SHGetFolderPath = windll.shell32.SHGetFolderPathW
_SHGetFolderPath.argtypes = [wintypes.HWND,
                            ctypes.c_int,
                            wintypes.HANDLE,
                            wintypes.DWORD, wintypes.LPCWSTR]


path_buf = wintypes.create_unicode_buffer(wintypes.MAX_PATH)
result = _SHGetFolderPath(0, CSIDL_LOCAL_APPDATA, 0, 0, path_buf)

print path_buf.value