NonInheritingInterfaces.cs

void Main()
{
	Mapper.CreateMap<iclass1, iclass1DTO>();
	Mapper.CreateMap<iclass2, iclass2DTO>();

	try
	{
		Mapper.AssertConfigurationIsValid();
		var bo = new class2 { prop1 = "PROP1", prop2 = "PROP2" };
	
		Mapper.Map(bo, new class2DTO()).Dump();
		//typeof(class4).GetInterfaces().Where(i=>typeof(class4).GetInterfaceMap(i).TargetMethods.Any(m=>m.DeclaringType==typeof(class4))).Dump();
	}
	catch(Exception ex)
	{
		ex.ToString().Dump();
	}
}

public class class1 : iclass1
{
   public string prop1 { get;set;}
}

public class class2 : class1, iclass2
{
   public string prop2 { get; set; }
}

public class class1DTO : iclass1DTO
{
   public string prop1 { get; set; }
}

public class class2DTO : class1DTO, iclass2DTO
{
   public string prop2 { get; set; }
}

public interface iclass1
{
   string prop1 { get; set; }
}

public interface iclass2
{
   string prop2 { get; set; }
}

public interface iclass1DTO
{
   string prop1 { get; set; }
}

public interface iclass2DTO
{
   string prop2 { get; set; }
}