Apache 2's a2ensite and a2dissite for non-Deb based distros. Source (slightly modified): Apache virtual hosting in CentOS http://www.tecmint.com/apache-virtual-hosting-in-centos/

a2dissite.sh

#!/bin/bash
avail=/etc/httpd/sites-enabled/$1.conf
enabled=/etc/httpd/sites-enabled
site=`ls /etc/httpd/sites-enabled/`

if [ "$#" != "1" ]; then
  echo "Use script: a2dissite virtual_site"
  echo -e "\nAvailable virtual hosts: \n$site"
  exit 0
else
  if test -e $avail; then
    sudo rm  $avail
  else
    echo -e "$avail virtual host does not exist! Exiting!"
    exit 0
  fi
  if test -e $enabled/$1.conf; then
    echo "Error! Could not remove $avail virtual host!"
  else
    echo  -e "Success! $avail has been removed!"
    exit 0
  fi
fi

a2ensite.sh

#!/bin/bash/

if test -d /etc/httpd/sites-available && test -d /etc/httpd/sites-enabled  ; then
  echo "-----------------------------------------------"
else
  mkdir -p /etc/httpd/sites-available
  mkdir -p /etc/httpd/sites-enabled
fi

avail=/etc/httpd/sites-available/$1.conf
enabled=/etc/httpd/sites-enabled/
site=`ls /etc/httpd/sites-available/`

if [ "$#" != "1" ]; then
  echo "Use script: a2ensite virtual_site"
  echo -e "\nAvailable virtual hosts:\n$site"
  exit 0
else
  if test -e $avail; then
    sudo ln -s $avail $enabled
  else
    echo -e "$avail virtual host does not exist! Please create one!\n$site"
    exit 0
  fi
  if test -e $enabled/$1.conf; then
    echo "Site ${1} enabled successfully"
  else
    echo  -e "Virtual host $avail does not exist!\nPlease see available virtual hosts:\n$site"
    exit 0
  fi
fi