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convert FREEC ratio.txt file to bedGraph format
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""" | |
Chromosome Start Ratio MedianRatio CopyNumber | |
1 1 -1 -1 5 | |
1 9854 4.28786 2.74942 5 | |
1 19707 3.38082 2.74942 5 | |
1 29560 2.56094 2.74942 5 | |
1 39413 2.87198 2.74942 5 | |
1 49266 2.47 2.74942 5 | |
1 59119 2.62686 2.74942 5 | |
1 68972 2.0109 1.81246 4 | |
1 78825 1.51216 1.81246 4 | |
""" | |
import argparse | |
with args.txt as infile, args.bedgraph as outfile: | |
header = next(infile) | |
prev_rname = None | |
prev_start = None | |
prev_cn = cn | |
for line in infile: | |
rname, start, ratio, med, cn = line.split() | |
if rname == prev_rname: | |
outfile.write("chr{0}\t{1}\t{2}\t{3}\n".format(rname, start, prev_start, prev_cn)) | |
prev_start = start | |
prev_cn = cn | |
elif rname != prev_rname: | |
prev_rname = rname | |
prev_start = start | |
prev_cn = cn | |
outfile.write("chr{0}\t{1}\t{2}\t{3}\n".format(rname, start, prev_start, prev_cn)) | |
def main(): | |
parser = argparse.ArgumentParser(prog='freec2bedgraph', description="Convert FREEC ratio.txt file to bedgraph format") | |
parser.add_argument('txt', type=argparse.FileType('r', 1), help="FREEC ratio.txt file (- as stdin)") | |
parser.add_argument('bedgraph', type=argparse.FileType('w', 4096), help="bedgraph output file (- as stdout)") | |
args = parser.parse_args() | |
freec2bedgraph(args) | |
if __name__ == "__main__": | |
main() |
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