This is a test plugin that tests if a image field type in a custom post meta box of Admin Page Framework causes a conflict with the featured image's image uploader.

admin-page-framework-test-featured-image-conflict.php

<?php
/* Plugin Name: Admin Page Framework Test - Featured Image Conflict */ 

if ( ! class_exists( 'AdminPageFramework' ) ) {
    $_sFrameworkPath = defined( 'WP_DEBUG' ) && WP_DEBUG
        ? dirname( dirname( __FILE__ ) ) . '/admin-page-framework/development/admin-page-framework.php'
        : dirname( dirname( __FILE__ ) ) . '/admin-page-framework/library/admin-page-framework.min.php';
    if ( file_exists( $_sFrameworkPath  ) ) {
        include( $_sFrameworkPath  );
    } else {
        trigger_error( 'Admin Page Framework: The framework path could not be located.', E_USER_NOTICE );    
        return;
    }
}

class APFTest_FeaturedImageConflict extends AdminPageFramework_MetaBox {

    public function setUp() {

        $this->addSettingFields(
            array(
                'field_id'          => 'image_test',
                'type'              => 'image',
                'title'             => 'testing',
            )
        );

    }

}

new APFTest_FeaturedImageConflict(
    null,        // id - null to auto-generate
    'Test - Featured Image Conflict', // title
    array( 'post' ),    // post, page, etc.
    'normal',
    'high'
);