parser.rb

#/usr/bin/env ruby

def open_t_delimited_file(filename)
  h = {}
   open(filename) {|f|
    f.each_line do |line|
      a = line.split("\t")
      h[a[0]] = a
    end
  }
  puts filename + " was loaded."
  h
end

if __FILE__ == $PROGRAM_NAME
  b = open_t_delimited_file(ARGV[0])

  open("b_hash.dump","wb") {|f|
    Marshal.dump(b,f)
  }
end

test.rb

#/usr/bin/env ruby

open("b_hash.dump","rb") {|f|
  str = Marshal.load(f)
  puts str["NM_001081381"]
}