gistfile1.txt

$ python routetest.py 
/
>>> group_list(www2)
/aha
>>> jot_list(www2, aha, None)
/aha:blah
>>> jot_list(www2, aha, blah)

routetest.py

from flask import Flask

app = Flask(__name__)
app.config['SERVER_NAME'] = 'lvh.me:5000'

# lvh.me:5000 routes back to localhost so you can test subdomains locally
# with sub.lvh.me:5000

# sub.lvh.me:5000/ should only trigger this group_list route

@app.route('/', subdomain='<area>')
def group_list(area='www', group=None, subgroup=None):
    return "group_list(%s)" % area


# but for some reason, this route is also picking it up.
# you can see in the console that both group_list & jot_list run

@app.route('/<group>:<subgroup>', subdomain='<area>')
@app.route('/<group>', subdomain='<area>')
def jot_list(area='www', group='general', subgroup=None):
    return "jot_list(%s, %s, %s)" % (area, group, subgroup)


c = app.test_client()
def test(url, subdomain='www2'):
    print url
    print '>>>', c.get(url, base_url='http://%s.lvh.me:5000/' % subdomain).data


test('/')
test('/aha')
test('/aha:blah')