Demo of using https://github.com/natevw/node-rf24 to pongpack to e.g. https://github.com/stanleyseow/RF24/blob/master/examples/pingpair/pingpair.ino

node-nrf_pongback.js

// see https://gist.github.com/natevw/5789019 for pins

var NRF24 = require("./index"),
    spiDev = "/dev/spidev0.0",
    cePin = 24, irqPin = 25,            //var ce = require("./gpio").connect(cePin)
    pipes = [0xF0F0F0F0E1, 0xF0F0F0F0D2];

var nrf = NRF24.connect(spiDev, cePin, irqPin);
nrf.channel(0x4c).transmitPower('PA_MAX').dataRate('1Mbps').crcBytes(2).autoRetransmit({count:15, delay:500}).begin(function () {
    var rx = nrf.openPipe('rx', pipes[0]),
        tx = nrf.openPipe('tx', pipes[1]);
    rx.on('data', function (d) {
        console.log("Got data, will respond", d.readUInt32BE(0));
        tx.write(d);
    });
    tx.on('error', function (e) {
        console.warn("Error sending reply.", e);
    });
});