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plagiat
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| # -*- coding: utf-8 -*- | |
| #!/usr/local/bin/python2.7 | |
| import sys | |
| import csv | |
| from argparse import ArgumentParser | |
| from argparse import RawDescriptionHelpFormatter | |
| import traceback | |
| import itertools | |
| from fuzzywuzzy import fuzz | |
| # base comparison method -- any comparison method has to inherit it | |
| class Comparison(object): | |
| # TODO consider storing whole row, instead of a title | |
| # so a link to an article can be given when displaying results | |
| def __init__(self, titles, lowercase): | |
| self.titles = 2*[None] | |
| if (lowercase): | |
| self.titles[0] = titles[0].lower() | |
| self.titles[1] = titles[1].lower() | |
| else: | |
| self.titles[0] = titles[0] | |
| self.titles[1] = titles[1] | |
| def setMetric(self, metric): | |
| self.metric = metric | |
| def toString(self): | |
| s = "M=" + str(self.metric) + "\n" | |
| s = s + "- " + self.titles[0] + "\n" | |
| s = s + "- " + self.titles[1] + "\n" | |
| return s | |
| # comparison method #1 | |
| class ComparisonTokenSet(Comparison): | |
| def __init__(self, titles, lowercase): | |
| super(ComparisonTokenSet, self).__init__(titles, lowercase) | |
| super(ComparisonTokenSet, self).setMetric(fuzz.token_set_ratio(self.titles[0], self.titles[1])) | |
| # comparison method #2 | |
| class ComparisonTokenSort(Comparison): | |
| def __init__(self, titles, lowercase): | |
| super(ComparisonTokenSort, self).__init__(titles, lowercase) | |
| super(ComparisonTokenSort, self).setMetric(fuzz.token_sort_ratio(self.titles[0], self.titles[1])) | |
| # util function to get list of comparison methods - to verify cmdline validity | |
| def getComparisonMethods(): | |
| return map(lambda x: x.__name__, Comparison.__subclasses__()) | |
| # util function go get comparison object type based on a string passed from cmdline | |
| def getComparisonType(method): | |
| return next((x for x in Comparison.__subclasses__() if x.__name__ == method), None) | |
| def calculateCombinationsNumber(titlesNumber): | |
| return titlesNumber * (titlesNumber-1) / 2 | |
| # print iterations progress - https://stackoverflow.com/questions/3173320/text-progress-bar-in-the-console | |
| def printProgress(iteration, total, prefix='', suffix='', decimals=1, bar_length=100): | |
| """ | |
| Call in a loop to create terminal progress bar | |
| @params: | |
| iteration - Required : current iteration (Int) | |
| total - Required : total iterations (Int) | |
| prefix - Optional : prefix string (Str) | |
| suffix - Optional : suffix string (Str) | |
| decimals - Optional : positive number of decimals in percent complete (Int) | |
| bar_length - Optional : character length of bar (Int) | |
| """ | |
| str_format = "{0:." + str(decimals) + "f}" | |
| percents = str_format.format(100 * (iteration / float(total))) | |
| filled_length = int(round(bar_length * iteration / float(total))) | |
| bar = '█' * filled_length + '-' * (bar_length - filled_length) | |
| sys.stdout.write('\r%s |%s| %s%s %s' % (prefix, bar, percents, '%', suffix)), | |
| if iteration == total: | |
| sys.stdout.write('\n') | |
| sys.stdout.flush() | |
| # bells and whistles; reads .csv file, creates requested comparisons, and returns list of results | |
| def dumpstat(inputfile="pubmed_result.csv", limitinput=5, limitoutput=5, method='tokenset', lowercase=True): | |
| if method not in getComparisonMethods(): | |
| raise NotImplementedError("method " + method + " is not implemented") | |
| # list of titles limited to 'limitoutput' | |
| titles = [] | |
| # read .csv with entries | |
| with open(inputfile, mode="r") as fv: | |
| reader = csv.DictReader(fv) | |
| index = 0 | |
| for row in reader: | |
| # respect the limits | |
| index = index + 1 | |
| if (index > limitinput): | |
| break | |
| # skip malformed rows -- not sure why we're getting them | |
| if (row['Title'] == 'Title'): | |
| continue | |
| titles.append(row['Title']) | |
| # list of comparisons | |
| # FIXME can be lower than calculated if file is a small one | |
| totalComparisons = calculateCombinationsNumber(limitinput) | |
| comparisons = [] | |
| # TODO run comparisons in parallel | |
| index = 0 | |
| for pair in itertools.combinations(titles, r=2): | |
| c = getComparisonType(method)(pair, lowercase) | |
| # FIXME wasting a lot of memory here makes it impossible to work on big sets. | |
| # Maybe append only if better than worst of top 'limitinput' best ones | |
| # and use a fixed-width container capped to 'limitinput' | |
| comparisons.append(c) | |
| if ((index % 1000) == 0): | |
| printProgress(index, totalComparisons, "Working... ") | |
| index = index + 1 | |
| printProgress(totalComparisons, totalComparisons, "Compared!") | |
| # sort the comparison results, so better ones are first | |
| comparisons.sort(key=lambda x: x.metric, reverse=True) | |
| # display results | |
| index = 0 | |
| for c in comparisons: | |
| if (index > limitoutput): | |
| break | |
| print (c.toString()) | |
| index = index + 1 | |
| def main(argv=None): # IGNORE:C0111 | |
| '''Command line options.''' | |
| if argv is None: | |
| argv = sys.argv | |
| else: | |
| sys.argv.extend(argv) | |
| try: | |
| # Setup argument parser | |
| parser = ArgumentParser(formatter_class=RawDescriptionHelpFormatter) | |
| parser.add_argument("--verbose", dest="verbose", action='store_true', help="be verbose", default=True) | |
| parser.add_argument("--lowercase", dest="lowercase", action='store_true', help="make lowercase before comparison") | |
| parser.add_argument("--limitinput", dest="limitinput", type=int, help="number of titles to compare", default=sys.maxint) | |
| parser.add_argument("--limitoutput", dest="limitoutput", type=int, help="number of comparisons to return", default=10) | |
| parser.add_argument("--data", dest="filedata", nargs='?', help="file to read titles from [default: %(default)s]", default='pubmed_result.csv') | |
| parser.add_argument("--method", dest="method", nargs='?', help="comparison method to use, one of: {" + ', '.join(getComparisonMethods()) + "} [default: %(default)s]", default=getComparisonMethods()[0]) | |
| # Process arguments | |
| args = parser.parse_args() | |
| if (args.verbose): | |
| print "=====" | |
| print "data = " + args.filedata | |
| print "limitinput = " + str(args.limitinput) | |
| print "limitoutput = " + str(args.limitoutput) | |
| print "method = " + str(args.method) | |
| print "lowercase = " + str(args.lowercase) | |
| print "=====" | |
| print "max number of combinations to check: " + str(calculateCombinationsNumber(args.limitinput)) | |
| dumpstat(args.filedata, args.limitinput, args.limitoutput, args.method, args.lowercase) | |
| except KeyboardInterrupt: | |
| ### handle keyboard interrupt ### | |
| return 0 | |
| except Exception, e: | |
| traceback.print_exc() | |
| return 2 | |
| if __name__ == "__main__": | |
| sys.exit(main()) |
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| michal@e6540:~/workspace/liclipse/plagiat$ time python ./plagiat.py --lowercase --limitoutput 300 --limitinput 5500 --method ComparisonTokenSet | |
| ===== | |
| data = pubmed_result.csv | |
| limitinput = 5500 | |
| limitoutput = 300 | |
| method = ComparisonTokenSet | |
| lowercase = True | |
| ===== | |
| max number of combinations to check: 15122250 | |
| Compared! |████████████████████████████████████████████████████████████████████████████████████████████████████| 100.0% | |
| M=100 | |
| - pathogenesis of lafora disease: transition of soluble glycogen to insoluble polyglucosan. | |
| - lafora disease. | |
| M=100 | |
| - cloning mice. | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| M=100 | |
| - cloning mice. | |
| - from cloning neural development genes to functional studies in mice, 30 years of advancements. | |
| M=100 | |
| - corrigendum: asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| - asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| M=100 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=100 | |
| - erratum: genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| - genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| M=100 | |
| - abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in lafora disease. | |
| - lafora disease. | |
| M=100 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - cloning-free crispr. | |
| M=100 | |
| - the evolutionary capacitor hsp90 buffers the regulatory effects of mammalian endogenous retroviruses. | |
| - mammalian endogenous retroviruses. | |
| M=100 | |
| - liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency. | |
| - arginase-1 deficiency. | |
| M=100 | |
| - pronuclear injection-based targeted transgenesis. | |
| - one-step generation of multiple transgenic mouse lines using an improved pronuclear injection-based targeted transgenesis (i-pitt). | |
| M=100 | |
| - erratum to: trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| - trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum to: cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| - cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| M=100 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=100 | |
| - arginase-1 deficiency. | |
| - strategies to rescue the consequences of inducible arginase-1 deficiency in mice. | |
| M=100 | |
| - corrigendum: extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| - extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=98 | |
| - activity-dependent dynamics of the transcription factor of camp-response element binding protein in cortical neurons revealed by single-molecule imaging. | |
| - activity-dependent dynamics of the transcription factor creb in cortical neurons revealed by single-molecule imaging. | |
| M=97 | |
| - erratum to: deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| - deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=96 | |
| - runx3 in immunity, inflammation and cancer. | |
| - runx3 at the interface of immunity, inflammation and cancer. | |
| M=96 | |
| - single-cell transcriptome and epigenomic reprogramming of cardiomyocyte-derived cardiac progenitor cells. | |
| - epigenomic reprogramming of adult cardiomyocyte-derived cardiac progenitor cells. | |
| M=95 | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. ii. the nmri/cd and cd/ta hybrid strains. | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. i. the cd/cremona hybrid strain. | |
| M=93 | |
| - crispr libraries and screening. | |
| - coralina: a universal method for the generation of grna libraries for crispr-based screening. | |
| M=93 | |
| - identification and functional analysis of long non-coding rnas in human and mouse early embryos based on single-cell transcriptome data. | |
| - identification and analysis of mouse non-coding rna using transcriptome data. | |
| M=93 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| M=92 | |
| - single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. | |
| - postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. | |
| M=92 | |
| - genome editing in mouse zygotes and embryonic stem cells by introducing sgrna/cas9 expressing plasmids. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=92 | |
| - a mouse model of hereditary coproporphyria identified in an enu mutagenesis screen. | |
| - enu mutagenesis in the mouse. | |
| M=92 | |
| - somatic genome editing goes viral. | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| M=92 | |
| - toll-like receptors: potential targets for lupus treatment. | |
| - toll-like receptors in systemic lupus erythematosus: potential for personalized treatment. | |
| M=91 | |
| - circadian control of global transcription. | |
| - chip-seq and rna-seq methods to study circadian control of transcription in mammals. | |
| M=90 | |
| - continuous blockade of cxcr4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells. | |
| - ex vivo expansion of hematopoietic stem cells. | |
| M=90 | |
| - divergence patterns of genic copy number variation in natural populations of the house mouse (mus musculus domesticus) reveal three conserved genes with major population-specific expansions. | |
| - genomic copy number variation in mus musculus. | |
| M=89 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - role of the dna repair glycosylase ogg1 in the activation of murine splenocytes. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=89 | |
| - cellular reprogramming, genome editing, and alternative crispr cas9 technologies for precise gene therapy of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - male infertility is responsible for nearly half of the extinction observed in the mouse collaborative cross. | |
| - genomes of the mouse collaborative cross. | |
| M=89 | |
| - muscle-specific crispr/cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - the potential role of 8-oxoguanine dna glycosylase-driven dna base excision repair in exercise-induced asthma. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - exploring novel candidate genes from the mouse genome informatics database: potential implications for avian migration research. | |
| - mouse genome database 2016. | |
| M=89 | |
| - mouse genome database 2016. | |
| - dbsuper: a database of super-enhancers in mouse and human genome. | |
| M=89 | |
| - mouse genome database 2016. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=89 | |
| - mouse genome database 2016. | |
| - mouse genome database: from sequence to phenotypes and disease models. | |
| M=89 | |
| - single-step generation of conditional knockout mouse embryonic stem cells. | |
| - rapid knockout and reporter mouse line generation and breeding colony establishment using eucomm conditional-ready embryonic stem cells: a case study. | |
| M=89 | |
| - a central role of trax in the atm-mediated dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=88 | |
| - combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models. | |
| - development of humanized mice in the age of genome editing. | |
| M=88 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=88 | |
| - genome editing in mouse and rat by electroporation. | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| M=88 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - [genome editing in mouse with crispr/cas system]. | |
| M=87 | |
| - replication study: melanoma genome sequencing reveals frequent prex2 mutations. | |
| - registered report: melanoma genome sequencing reveals frequent prex2 mutations. | |
| M=87 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=87 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=87 | |
| - genome editing in mice using tale nucleases. | |
| - genome editing in mouse spermatogonial stem/progenitor cells using engineered nucleases. | |
| M=86 | |
| - hotspots of de novo point mutations in induced pluripotent stem cells. | |
| - the number of point mutations in induced pluripotent stem cells and nuclear transfer embryonic stem cells depends on the method and somatic cell type used for their generation. | |
| M=86 | |
| - data on the effect of in utero exposure to polycyclic aromatic hydrocarbons on genome-wide patterns of dna methylation in lung tissues. | |
| - dna methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons. | |
| M=86 | |
| - crispr/cas9 - mediated precise targeted integration in vivo using a double cut donor with short homology arms. | |
| - homology-mediated end joining-based targeted integration using crispr/cas9. | |
| M=86 | |
| - effective biomedical document classification for identifying publications relevant to the mouse gene expression database (gxd). | |
| - the mouse gene expression database (gxd): 2017 update. | |
| M=86 | |
| - initial characterization of behavior and ketamine response in a mouse knockout of the post-synaptic effector gene anks1b. | |
| - the eif2a knockout mouse. | |
| M=86 | |
| - single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types. | |
| - evolution of the unspliced transcriptome. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - exome-wide single-base substitutions in tissues and derived cell lines of the constitutive fhit knockout mouse. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - beyond knockouts: the international knockout mouse consortium delivers modular and evolving tools for investigating mammalian genes. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - utilising the resources of the international knockout mouse consortium: the australian experience. | |
| M=86 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - gene therapies that restore dystrophin expression for the treatment of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=86 | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=86 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - application of comparative transcriptional genomics to identify molecular targets for pediatric ibd. | |
| M=86 | |
| - excavating the genome: large-scale mutagenesis screening for the discovery of new mouse models. | |
| - enu mutagenesis in the mouse. | |
| M=85 | |
| - landscape of dna methylation on the marsupial x. | |
| - influence of the prader-willi syndrome imprinting center on the dna methylation landscape in the mouse brain. | |
| M=85 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| M=85 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| M=85 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - functional validation of tensin2 sh2-ptb domain by crispr/cas9-mediated genome editing. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - crispr/cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - generation of an oocyte-specific cas9 transgenic mouse for genome editing. | |
| M=85 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - self-cloning crispr. | |
| M=85 | |
| - self-cloning crispr. | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| M=85 | |
| - self-cloning crispr. | |
| - cloning-free crispr. | |
| M=85 | |
| - the role of mdm2 amplification and overexpression in tumorigenesis. | |
| - gene amplification-associated overexpression of the rna editing enzyme adar1 enhances human lung tumorigenesis. | |
| M=85 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| - cloning-free crispr. | |
| M=85 | |
| - assessment of microrna expression in mouse epididymal epithelial cells and spermatozoa by next generation sequencing. | |
| - next generation sequencing analysis reveals segmental patterns of microrna expression in mouse epididymal epithelial cells. | |
| M=85 | |
| - transcriptional response in mouse thyroid tissue after 211at administration: effects of absorbed dose, initial dose-rate and time after administration. | |
| - transcriptional response in normal mouse tissues after i.v. (211)at administration - response related to absorbed dose, dose rate, and time. | |
| M=84 | |
| - amino acid substitutions associated with avian h5n6 influenza a virus adaptation to mice. | |
| - amino acid substitutions involved in the adaptation of a novel highly pathogenic h5n2 avian influenza virus in mice. | |
| M=84 | |
| - genome editing in mouse and rat by electroporation. | |
| - efficient crispr/cas9-mediated genome editing in mice by zygote electroporation of nuclease. | |
| M=84 | |
| - p53 and tap63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - collaborative cross and diversity outbred data resources in the mouse phenome database. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - informatics resources for the collaborative cross and related mouse populations. | |
| M=84 | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| - complete genome sequence of turicibacter sp. strain h121, isolated from the feces of a contaminated germ-free mouse. | |
| M=84 | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| - the genetic architecture of nafld among inbred strains of mice. | |
| M=83 | |
| - pd-l1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome informatics (mgi) resource: genetic, genomic, and biological knowledgebase for the laboratory mouse. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - effects of expressing human t-cell leukemia virus type 1 (htlv-i) oncoprotein tax on dok1, dok2 and dok3 gene expression in mice. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - human t-cell leukemia virus type 1 (htlv-1) tax requires cadm1/tslc1 for inactivation of the nf-κb inhibitor a20 and constitutive nf-κb signaling. | |
| M=83 | |
| - shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the united states. | |
| - zinc and diabetes. | |
| M=83 | |
| - a five-repeat micro-dystrophin gene ameliorated dystrophic phenotype in the severe dba/2j-mdx model of duchenne muscular dystrophy. | |
| - jagged 1 rescues the duchenne muscular dystrophy phenotype. | |
| M=83 | |
| - engineered epidermal progenitor cells can correct diet-induced obesity and diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - tex19.1 promotes spo11-dependent meiotic recombination in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=83 | |
| - identification and characterization of a foxa2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls gckr expression in liver cells. | |
| - zinc and diabetes. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=83 | |
| - expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion. | |
| - zinc and diabetes. | |
| M=83 | |
| - targeted dna methylation in pericentromeres with genome editing-based artificial dna methyltransferase. | |
| - editing dna methylation in the mammalian genome. | |
| M=83 | |
| - using hescs to probe the interaction of the diabetes-associated genes cdkal1 and mt1e. | |
| - zinc and diabetes. | |
| M=83 | |
| - dna modifications and alzheimer's disease. | |
| - modifiers and readers of dna modifications and their impact on genome structure, expression, and stability in disease. | |
| M=83 | |
| - the zinc finger e-box-binding homeobox 1 (zeb1) promotes the conversion of mouse fibroblasts into functional neurons. | |
| - chemical conversion of mouse fibroblasts into functional dopaminergic neurons. | |
| M=83 | |
| - genetic and small molecule disruption of the aid/rad51 axis similarly protects nonobese diabetic mice from type 1 diabetes through expansion of regulatory b lymphocytes. | |
| - zinc and diabetes. | |
| M=83 | |
| - long-term alterations to dna methylation as a biomarker of prenatal alcohol exposure: from mouse models to human children with fetal alcohol spectrum disorders. | |
| - associative dna methylation changes in children with prenatal alcohol exposure. | |
| M=83 | |
| - genetics of obesity: can an old dog teach us new tricks? | |
| - systems genetics of obesity. | |
| M=83 | |
| - the transcription factor nfatc2 regulates β-cell proliferation and genes associated with type 2 diabetes in mouse and human islets. | |
| - zinc and diabetes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - visualization of results from systems genetics studies in chromosomal context. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a suite of tools for biologists that improve accessibility and visualization of large systems genetics datasets: applications to the hybrid mouse diversity panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - defining the influence of germline variation on metastasis using systems genetics approaches. | |
| M=83 | |
| - systems genetics of obesity. | |
| - the hybrid mouse diversity panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics of intravenous cocaine self-administration in the bxd recombinant inbred mouse panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - application of quantitative metabolomics in systems genetics in rodent models of complex phenotypes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a systems genetics study of swine illustrates mechanisms underlying human phenotypic traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics identifies sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus. | |
| M=83 | |
| - emerging roles of glis3 in neonatal diabetes, type 1 and type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - differential gene dosage effects of diabetes-associated gene glis3 in pancreatic β cell differentiation and function. | |
| - zinc and diabetes. | |
| M=83 | |
| - transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms. | |
| - enu mutagenesis in the mouse. | |
| M=83 | |
| - inhibition of dna methyltransferase 1 increases nuclear receptor subfamily 4 group a member 1 expression and decreases blood glucose in type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - microinjection-based generation of mutant mice with a double mutation and a 0.5 mb deletion in their genome by the crispr/cas9 system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=83 | |
| - an integrative study identifies kcnc2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the korean population. | |
| - zinc and diabetes. | |
| M=83 | |
| - structural organization of the inactive x chromosome in the mouse. | |
| - bipartite structure of the inactive mouse x chromosome. | |
| M=83 | |
| - zinc and diabetes. | |
| - serotonin as a new therapeutic target for diabetes mellitus and obesity. | |
| M=83 | |
| - zinc and diabetes. | |
| - unexpected partial correction of metabolic and behavioral phenotypes of alzheimer's app/psen1 mice by gene targeting of diabetes/alzheimer's-related sorcs1. | |
| M=83 | |
| - zinc and diabetes. | |
| - type 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic association of long-chain acyl-coa synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis. | |
| M=83 | |
| - zinc and diabetes. | |
| - a20 inhibits β-cell apoptosis by multiple mechanisms and predicts residual β-cell function in type 1 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the nod mouse reveals significant gene enrichment on chromosomes 6 and 7. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptpn22 and cd2 variations are associated with altered protein expression and susceptibility to type 1 diabetes in nonobese diabetic mice. | |
| M=83 | |
| - zinc and diabetes. | |
| - phenotypic characterization of mice carrying homozygous deletion of klf11, a gene in which mutations cause human neonatal and mody vii diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptprd silencing by dna hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - the pathogenic role of persistent milk signaling in mtorc1- and milk-microrna-driven type 2 diabetes mellitus. | |
| M=83 | |
| - sequence diversity, intersubgroup relationships, and origins of the mouse leukemia gammaretroviruses of laboratory and wild mice. | |
| - origins of the endogenous and infectious laboratory mouse gammaretroviruses. | |
| M=83 | |
| - rag2 and xlf/cernunnos interplay reveals a novel role for the rag complex in dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - nuclear localization of the dna repair scaffold xrcc1: uncovering the functional role of a bipartite nls. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - genomic copy number variation in mus musculus. | |
| - connecting anxiety and genomic copy number variation: a genome-wide analysis in cd-1 mice. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - piggybac transposon-based insertional mutagenesis in mouse haploid embryonic stem cells. | |
| M=82 | |
| - genome-wide discovery of long intergenic noncoding rnas and their epigenetic signatures in the rat. | |
| - mutations in the noncoding genome. | |
| M=82 | |
| - replication stress in hematopoietic stem cells in mouse and man. | |
| - a short g1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. | |
| M=82 | |
| - complete genome sequence of a strain of bifidobacterium pseudolongum isolated from mouse feces and associated with improved organ transplant outcome. | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| M=82 | |
| - highly variable genomic landscape of endogenous retroviruses in the c57bl/6j inbred strain, depending on individual mouse, gender, organ type, and organ location. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - a modifier of huntington's disease onset at the mlh1 locus. | |
| - chromosome substitution strain assessment of a huntington's disease modifier locus. | |
| M=82 | |
| - a14 comprehensive characterisation and evolutionary analysis of endogenous retroviruses in the mouse genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=82 | |
| - the hope and hype of crispr-cas9 genome editing: a review. | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| M=82 | |
| - detection of rna polymerase ii in mouse embryos during zygotic genome activation using immunocytochemistry. | |
| - rna fish to study zygotic genome activation in early mouse embryos. | |
| M=82 | |
| - identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts. | |
| - generation of integration-free induced neural stem cells from mouse fibroblasts. | |
| M=82 | |
| - comparative dynamics of 5-methylcytosine reprogramming and tet family expression during preimplantation mammalian development in mouse and sheep. | |
| - maternal sin3a regulates reprogramming of gene expression during mouse preimplantation development. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9 mediated genome editing in es cells and its application for chimeric analysis in mice. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9-mediated insertion of loxp sites in the mouse dock7 gene provides an effective alternative to use of targeted embryonic stem cells. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - generating crispr/cas9 mediated monoallelic deletions to study enhancer function in mouse embryonic stem cells. | |
| M=82 | |
| - integration and fixation preferences of human and mouse endogenous retroviruses uncovered with functional data analysis. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - precision cancer mouse models through genome editing with crispr-cas9. | |
| M=82 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=82 | |
| - improved genome editing efficiency and flexibility using modified oligonucleotides with talen and crispr-cas9 nucleases. | |
| - genome editing in mice using tale nucleases. | |
| M=82 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - insertion of sequences at the original provirus integration site of mouse rosa26 locus using the crispr/cas9 system. | |
| M=82 | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=82 | |
| - the role of human endogenous retroviruses in brain development and function. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - genomic landscapes of endogenous retroviruses unveil intricate genetics of conventional and genetically-engineered laboratory mouse strains. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - trim33 binds and silences a class of young endogenous retroviruses in the mouse testis; a novel component of the arms race between retrotransposons and the host genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - towards autotrophic tissue engineering: photosynthetic gene therapy for regeneration. | |
| - photosynthetic biomaterials: a pathway towards autotrophic tissue engineering. | |
| M=82 | |
| - mutations in the noncoding genome. | |
| - assessing recent selection and functionality at long noncoding rna loci in the mouse genome. | |
| M=82 | |
| - comprehensive dna methylation analysis of retrotransposons in male germ cells. | |
| - locus-specific dna methylation analysis of retrotransposons in es, somatic and cancer cells using high-throughput targeted repeat element bisulfite sequencing. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the histone methyltransferase setdb1 represses endogenous and exogenous retroviruses in b lymphocytes. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the krab zinc finger protein zfp809 is required to initiate epigenetic silencing of endogenous retroviruses. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the decline of human endogenous retroviruses: extinction and survival. | |
| M=81 | |
| - landscape of dna methylation on the marsupial x. | |
| - erratum to: deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=81 | |
| - landscape of dna methylation on the marsupial x. | |
| - deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=81 | |
| - knockdown of heat shock proteins hspa6 (hsp70b') and hspa1a (hsp70-1) sensitizes differentiated human neuronal cells to cellular stress. | |
| - differential targeting of hsp70 heat shock proteins hspa6 and hspa1a with components of a protein disaggregation/refolding machine in differentiated human neuronal cells following thermal stress. | |
| M=81 | |
| - knockdown of heat shock proteins hspa6 (hsp70b') and hspa1a (hsp70-1) sensitizes differentiated human neuronal cells to cellular stress. | |
| - dynamics of the association of heat shock protein hspa6 (hsp70b') and hspa1a (hsp70-1) with stress-sensitive cytoplasmic and nuclear structures in differentiated human neuronal cells. | |
| M=81 | |
| - replication stress in hematopoietic stem cells in mouse and man. | |
| - ssb1 and ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. | |
| M=81 | |
| - distinguishing states of arrest: genome-wide descriptions of cellular quiescence using chip-seq and rna-seq analysis. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - role of rad51ap1 in homologous recombination dna repair and carcinogenesis. | |
| - [the role of parp2 in dna repair]. | |
| M=81 | |
| - x chromosome evolution in cetartiodactyla. | |
| - a genome survey sequencing of the java mouse deer (tragulus javanicus) adds new aspects to the evolution of lineage specific retrotransposons in ruminantia (cetartiodactyla). | |
| M=81 | |
| - standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of kctd1 (i27n) mutant mice. | |
| - generation and standardized, systemic phenotypic analysis of pou3f3l423p mutant mice. | |
| M=81 | |
| - subpial adeno-associated virus 9 (aav9) vector delivery in adult mice. | |
| - adeno-associated virus vector mediated delivery of the hbv genome induces chronic hepatitis b virus infection and liver fibrosis in mice. | |
| M=81 | |
| - rna fish to study zygotic genome activation in early mouse embryos. | |
| - detection and characterization of small noncoding rnas in mouse gametes and embryos prior to zygotic genome activation. | |
| M=81 | |
| - chip-seq analysis of genomic binding regions of five major transcription factors highlights a central role for zic2 in the mouse epiblast stem cell gene regulatory network. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - a mouse tissue transcription factor atlas. | |
| - substituting mouse transcription factor pou4f2 with a sea urchin orthologue restores retinal ganglion cell development. | |
| M=81 | |
| - generation of lif-independent induced pluripotent stem cells from canine fetal fibroblasts. | |
| - identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts. | |
| M=81 | |
| - tracking the embryonic stem cell transition from ground state pluripotency. | |
| - jun-mediated changes in cell adhesion contribute to mouse embryonic stem cell exit from ground state pluripotency. | |
| M=81 | |
| - the mouse gene expression database (gxd): 2017 update. | |
| - the mouse gene expression database: new features and how to use them effectively. | |
| M=81 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=81 | |
| - motif oriented high-resolution analysis of chip-seq data reveals the topological order of ctcf and cohesin proteins on dna. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - [viral superantigens]. | |
| - convergent capture of retroviral superantigens by mammalian herpesviruses. | |
| M=81 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - therapeutic genome editing by combined viral and non-viral delivery of crispr system components in vivo. | |
| M=81 | |
| - liver chip-seq analysis in fgf19-treated mice reveals shp as a global transcriptional partner of srebp-2. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - csaw: a bioconductor package for differential binding analysis of chip-seq data using sliding windows. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - crystallization and x-ray diffraction analysis of the hmg domain of the chondrogenesis master regulator sox9 in complex with a chip-seq-identified dna element. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - description of an optimized chip-seq analysis pipeline dedicated to genome wide identification of e4f1 binding sites in primary and transformed mefs. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - de novo chip-seq analysis. | |
| - papst, a user friendly and powerful java platform for chip-seq peak co-localization analysis and beyond. | |
| M=81 | |
| - single-step generation of conditional knockout mouse embryonic stem cells. | |
| - conditional knockout mouse models of cancer. | |
| M=80 | |
| - crispr libraries and screening. | |
| - analysing the outcome of crispr-aided genome editing in embryos: screening, genotyping and quality control. | |
| M=80 | |
| - crispr libraries and screening. | |
| - compact and highly active next-generation libraries for crispr-mediated gene repression and activation. | |
| M=80 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=80 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9-mediated insertion of loxp sites in the mouse dock7 gene provides an effective alternative to use of targeted embryonic stem cells. | |
| M=80 | |
| - ribosomal dna copy number loss and sequence variation in cancer. | |
| - concerted copy number variation balances ribosomal dna dosage in human and mouse genomes. | |
| M=80 | |
| - protective efficacy of zika vaccine in ag129 mouse model. | |
| - comparative studies of infectivity, immunogenicity and cross-protective efficacy of live attenuated influenza vaccines containing nucleoprotein from cold-adapted or wild-type influenza virus in a mouse model. | |
| M=80 | |
| - protective efficacy of zika vaccine in ag129 mouse model. | |
| - putative function of hypothetical proteins expressed by clostridium perfringens type a strains and their protective efficacy in mouse model. | |
| M=80 | |
| - somatic genome editing with crispr/cas9 generates and corrects a metabolic disease. | |
| - somatic genome editing goes viral. | |
| M=80 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - generation of a knockout mouse embryonic stem cell line using a paired crispr/cas9 genome engineering tool. | |
| M=80 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=80 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - in vivo and in vitro disease modeling with crispr/cas9. | |
| M=80 | |
| - somatic genome editing goes viral. | |
| - modeling invasive lobular breast carcinoma by crispr/cas9-mediated somatic genome editing of the mammary gland. | |
| M=80 | |
| - somatic genome editing goes viral. | |
| - adenovirus-mediated somatic genome editing of pten by crispr/cas9 in mouse liver in spite of cas9-specific immune responses. | |
| M=80 | |
| - modification of three amino acids in sodium taurocholate cotransporting polypeptide renders mice susceptible to infection with hepatitis d virus in vivo. | |
| - hepatitis d virus infection of mice expressing human sodium taurocholate co-transporting polypeptide. | |
| M=80 | |
| - genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of alzheimer's disease. | |
| - genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism. | |
| M=80 | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=80 | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=80 | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| - efficient crispr/cas9-mediated genome editing in mice by zygote electroporation of nuclease. | |
| M=80 | |
| - mapping the genomic architecture of adaptive traits with interspecific introgressive origin: a coalescent-based approach. | |
| - interspecific introgressive origin of genomic diversity in the house mouse. | |
| M=80 | |
| - characterization of gene expression in mouse embryos at the 1-cell stage. | |
| - characterization of the structure and expression of mouse itpa gene and its related sequences in the mouse genome. | |
| M=80 | |
| - notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance. | |
| - a dual role for notch signaling in joint cartilage maintenance and osteoarthritis. | |
| M=80 | |
| - genome-wide analysis of histone acetylation dynamics during mouse embryonic stem cell neural differentiation. | |
| - genome-wide copy number profiling of mouse neural stem cells during differentiation. | |
| M=80 | |
| - transcriptional response in mouse thyroid tissue after 211at administration: effects of absorbed dose, initial dose-rate and time after administration. | |
| - dose-specific transcriptional responses in thyroid tissue in mice after (131)i administration. | |
| M=79 | |
| - efficient generation of genome-modified mice using campylobacter jejuni-derived crispr/cas. | |
| - zygote-mediated generation of genome-modified mice using streptococcus thermophilus 1-derived crispr/cas system. | |
| M=79 | |
| - composition and dosage of a multipartite enhancer cluster control developmental expression of ihh (indian hedgehog). | |
| - developmental expression of paraoxonase 2. | |
| M=79 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - [genome editing in mouse with crispr/cas system]. | |
| M=79 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - complex trait analyses of the collaborative cross: tools and databases. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - using the collaborative cross to study the role of genetic diversity in cancer-related phenotypes. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - influenza h3n2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in cast/eij mice. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - the founder strains of the collaborative cross express a complex combination of advantageous and deleterious traits for male reproduction. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - genome wide identification of sars-cov susceptibility loci using the collaborative cross. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - splicing landscape of the eight collaborative cross founder strains. | |
| M=79 | |
| - disrupting interactions between β-catenin and activating tcfs reconstitutes ground state pluripotency in mouse embryonic stem cells. | |
| - interactions between pluripotency factors specify cis-regulation in embryonic stem cells. | |
| M=79 | |
| - treatment of dyslipidemia using crispr/cas9 genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - comparative analysis of osteoblast gene expression profiles and runx2 genomic occupancy of mouse and human osteoblasts in vitro. | |
| - comparative transcriptomics in human and mouse. | |
| M=79 | |
| - comparative transcriptomics in human and mouse. | |
| - comprehensive comparative homeobox gene annotation in human and mouse. | |
| M=79 | |
| - comparative transcriptomics in human and mouse. | |
| - comparative analysis of genome maintenance genes in naked mole rat, mouse, and human. | |
| M=79 | |
| - a mouse tissue transcription factor atlas. | |
| - sex- and tissue-specific functions of drosophila doublesex transcription factor target genes. | |
| M=79 | |
| - development of humanized mice in the age of genome editing. | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| M=79 | |
| - dynamic landscape of alternative polyadenylation during retinal development. | |
| - regulation of alternative polyadenylation by nkx2-5 and xrn2 during mouse heart development. | |
| M=79 | |
| - genome-wide analysis of alternative splicing during human heart development. | |
| - genome-wide analysis of dna methylation dynamics during early human development. | |
| M=79 | |
| - amino acid substitutions involved in the adaptation of a novel highly pathogenic h5n2 avian influenza virus in mice. | |
| - adaptive amino acid substitutions enhance the virulence of a novel human h7n9 influenza virus in mice. | |
| M=79 | |
| - functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates bhlhe41. | |
| - functional characterization of rad52 as a lung cancer susceptibility gene in the 12p13.33 locus. | |
| M=79 | |
| - aav-mediated crispr/cas gene editing of retinal cells in vivo. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=79 | |
| - zygote-mediated generation of genome-modified mice using streptococcus thermophilus 1-derived crispr/cas system. | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| M=79 | |
| - crispr/cas9-mediated genome editing of mouse small intestinal organoids. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - sirt7 promotes genome integrity and modulates non-homologous end joining dna repair. | |
| - lrf maintains genome integrity by regulating the non-homologous end joining pathway of dna repair. | |
| M=79 | |
| - the impact of toxoplasma gondii on the mammalian genome. | |
| - affinity-seq detects genome-wide prdm9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage. | |
| M=79 | |
| - role of transient receptor potential ankyrin 1 channels in alzheimer's disease. | |
| - nuclear tau and its potential role in alzheimer's disease. | |
| M=79 | |
| - tox3 regulates neural progenitor identity. | |
| - re1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro. | |
| M=79 | |
| - developmental expression of paraoxonase 2. | |
| - distribution pattern of cytoplasmic organelles, spindle integrity, oxidative stress, octamer-binding transcription factor 4 (oct4) expression and developmental potential of oocytes following multiple superovulation. | |
| M=79 | |
| - developmental expression of paraoxonase 2. | |
| - expression of maternally derived khdc3, nlrp5, ooep and tle6 is associated with oocyte developmental competence in the ovine species. | |
| M=79 | |
| - developmental expression of paraoxonase 2. | |
| - developmental analysis of spliceosomal snrna isoform expression. | |
| M=79 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=79 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - adenovirus-mediated somatic genome editing of pten by crispr/cas9 in mouse liver in spite of cas9-specific immune responses. | |
| M=79 | |
| - editing of mouse and human immunoglobulin genes by crispr-cas9 system. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - improved genome editing efficiency and flexibility using modified oligonucleotides with talen and crispr-cas9 nucleases. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| M=79 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - adenovirus-mediated somatic genome editing of pten by crispr/cas9 in mouse liver in spite of cas9-specific immune responses. | |
| M=79 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - precision cancer mouse models through genome editing with crispr-cas9. | |
| M=79 | |
| - genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the nod mouse reveals significant gene enrichment on chromosomes 6 and 7. | |
| - genetic architecture of insulin resistance in the mouse. | |
| M=79 | |
| - genome wide mapping of ubf binding-sites in mouse and human cell lines. | |
| - genome-wide comparison of pu.1 and spi-b binding sites in a mouse b lymphoma cell line. | |
| M=79 | |
| - gnl3 and ska3 are novel prostate cancer metastasis susceptibility genes. | |
| - a systems genetics approach identifies cxcl14, itgax, and lpcat2 as novel aggressive prostate cancer susceptibility genes. | |
| M=79 | |
| - structure of slitrk2-ptpδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion. | |
| - mechanisms of splicing-dependent trans-synaptic adhesion by ptpδ-il1rapl1/il-1racp for synaptic differentiation. | |
| M=79 | |
| - wge: a crispr database for genome engineering. | |
| - mouse genome engineering via crispr-cas9 for study of immune function. | |
| M=79 | |
| - the genetic architecture of the genome-wide transcriptional response to er stress in the mouse. | |
| - genetic architecture of insulin resistance in the mouse. | |
| M=78 | |
| - rtfadb: a database of computationally predicted associations between retrotransposons and transcription factors in the human and mouse genomes. | |
| - the role of retrotransposons in gene family expansions in the human and mouse genomes. | |
| M=78 | |
| - dna polymerase β: a missing link of the base excision repair machinery in mammalian mitochondria. | |
| - [the role of parp2 in dna repair]. | |
| M=78 | |
| - dynamic landscape and regulation of rna editing in mammals. | |
| - global analysis of mouse polyomavirus infection reveals dynamic regulation of viral and host gene expression and promiscuous viral rna editing. | |
| M=78 | |
| - hoxa1 targets signaling pathways during neural differentiation of es cells and mouse embryogenesis. | |
| - dynamic regulation of nanog and stem cell-signaling pathways by hoxa1 during early neuro-ectodermal differentiation of es cells. | |
| M=78 | |
| - genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation. | |
| - genome-wide in vivo screen identifies novel host regulators of metastatic colonization. | |
| M=78 | |
| - whole exome sequencing reveals a functional mutation in the gain domain of the bai2 receptor underlying a forward mutagenesis hyperactivity qtl. | |
| - enu mutagenesis in the mouse. | |
| M=78 | |
| - genome organization drives chromosome fragility. | |
| - spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization. | |
| M=78 | |
| - genetic engineering as a tool for the generation of mouse models to understand disease phenotypes and gene function. | |
| - animal models of rls phenotypes. | |
| M=78 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - aav-mediated crispr/cas gene editing of retinal cells in vivo. | |
| M=78 | |
| - neuroanatomy in mouse models of rett syndrome is related to the severity of mecp2 mutation and behavioral phenotypes. | |
| - animal models of rls phenotypes. | |
| M=78 | |
| - genome-wide mapping of in vivo erα-binding sites in male mouse efferent ductules. | |
| - genome wide mapping of ubf binding-sites in mouse and human cell lines. | |
| M=78 | |
| - targeted deletion of an entire chromosome using crispr/cas9. | |
| - analysis of noncanonical calcium-dependent protein kinases in toxoplasma gondii by targeted gene deletion using crispr/cas9. | |
| M=78 | |
| - low-expression of tmem100 is associated with poor prognosis in non-small-cell lung cancer. | |
| - high expression of p62 protein is associated with poor prognosis and aggressive phenotypes in endometrial cancer. | |
| M=78 | |
| - dynamic regulation of small rnaome during the early stage of cardiac differentiation from pluripotent embryonic stem cells. | |
| - lack of rybp in mouse embryonic stem cells impairs cardiac differentiation. | |
| M=78 | |
| - mouse rif1 is a regulatory subunit of protein phosphatase 1 (pp1). | |
| - hepatic protein phosphatase 1 regulatory subunit 3b (ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - the transcription factor nfatc2 regulates β-cell proliferation and genes associated with type 2 diabetes in mouse and human islets. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - protein delivery of an artificial transcription factor restores widespread ube3a expression in an angelman syndrome mouse brain. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - compound hierarchical correlated beta mixture with an application to cluster mouse transcription factor dna binding data. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - re1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro. | |
| M=78 | |
| - runx3 in immunity, inflammation and cancer. | |
| - gene expression architecture of mouse dorsal and tail skin reveals functional differences in inflammation and cancer. | |
| M=78 | |
| - runx3 in immunity, inflammation and cancer. | |
| - chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer. | |
| M=78 | |
| - expanding the genetic code of mus musculus. | |
| - genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (mus musculus domesticus). | |
| M=78 | |
| - muscle-specific crispr/cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for duchenne muscular dystrophy. | |
| - in vivo genome editing improves muscle function in a mouse model of duchenne muscular dystrophy. | |
| M=78 | |
| - sex difference in egfr pathways in mouse kidney-potential impact on the immune system. | |
| - dcir in the "osteo-immune" system. | |
| real 14m25,818s | |
| user 14m21,128s | |
| sys 0m4,580s | |
| michal@e6540:~/workspace/liclipse/plagiat$ |
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| michal@e6540:~/workspace/liclipse/plagiat$ | |
| michal@e6540:~/workspace/liclipse/plagiat$ time python ./plagiat.py --lowercase --limitoutput 200 --limitinput 6000 --method ComparisonTokenSet && time python ./plagiat.py --lowercase --limitoutput 200 --limitinput 6000 --method ComparisonTokenSort | |
| ===== | |
| data = pubmed_result.csv | |
| limitinput = 6000 | |
| limitoutput = 200 | |
| method = ComparisonTokenSet | |
| lowercase = True | |
| ===== | |
| max number of combinations to check: 17997000 | |
| Compared! |████████████████████████████████████████████████████████████████████████████████████████████████████| 100.0% | |
| M=100 | |
| - pathogenesis of lafora disease: transition of soluble glycogen to insoluble polyglucosan. | |
| - lafora disease. | |
| M=100 | |
| - cloning mice. | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| M=100 | |
| - cloning mice. | |
| - from cloning neural development genes to functional studies in mice, 30 years of advancements. | |
| M=100 | |
| - corrigendum: asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| - asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| M=100 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=100 | |
| - erratum: genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| - genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| M=100 | |
| - abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in lafora disease. | |
| - lafora disease. | |
| M=100 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - cloning-free crispr. | |
| M=100 | |
| - the evolutionary capacitor hsp90 buffers the regulatory effects of mammalian endogenous retroviruses. | |
| - mammalian endogenous retroviruses. | |
| M=100 | |
| - liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency. | |
| - arginase-1 deficiency. | |
| M=100 | |
| - pronuclear injection-based targeted transgenesis. | |
| - one-step generation of multiple transgenic mouse lines using an improved pronuclear injection-based targeted transgenesis (i-pitt). | |
| M=100 | |
| - erratum to: trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| - trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum to: cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| - cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| M=100 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=100 | |
| - arginase-1 deficiency. | |
| - strategies to rescue the consequences of inducible arginase-1 deficiency in mice. | |
| M=100 | |
| - corrigendum: extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| - extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=100 | |
| - corrigendum to "disruption of the potassium channel regulatory subunit kcne2 causes iron-deficient anemia" [experimental hematology, vol. 42, issue 12, p1053-1058.e1]. | |
| - disruption of the potassium channel regulatory subunit kcne2 causes iron-deficient anemia. | |
| M=99 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - mouse genome editing using the crispr/cas system. | |
| M=98 | |
| - activity-dependent dynamics of the transcription factor of camp-response element binding protein in cortical neurons revealed by single-molecule imaging. | |
| - activity-dependent dynamics of the transcription factor creb in cortical neurons revealed by single-molecule imaging. | |
| M=97 | |
| - erratum to: deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| - deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=96 | |
| - runx3 in immunity, inflammation and cancer. | |
| - runx3 at the interface of immunity, inflammation and cancer. | |
| M=96 | |
| - single-cell transcriptome and epigenomic reprogramming of cardiomyocyte-derived cardiac progenitor cells. | |
| - epigenomic reprogramming of adult cardiomyocyte-derived cardiac progenitor cells. | |
| M=96 | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| - mouse genome editing using the crispr/cas system. | |
| M=95 | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. ii. the nmri/cd and cd/ta hybrid strains. | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. i. the cd/cremona hybrid strain. | |
| M=93 | |
| - crispr libraries and screening. | |
| - coralina: a universal method for the generation of grna libraries for crispr-based screening. | |
| M=93 | |
| - identification and functional analysis of long non-coding rnas in human and mouse early embryos based on single-cell transcriptome data. | |
| - identification and analysis of mouse non-coding rna using transcriptome data. | |
| M=93 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| M=92 | |
| - single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. | |
| - postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. | |
| M=92 | |
| - genome editing in mouse zygotes and embryonic stem cells by introducing sgrna/cas9 expressing plasmids. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=92 | |
| - a mouse model of hereditary coproporphyria identified in an enu mutagenesis screen. | |
| - enu mutagenesis in the mouse. | |
| M=92 | |
| - somatic genome editing goes viral. | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| M=92 | |
| - toll-like receptors: potential targets for lupus treatment. | |
| - toll-like receptors in systemic lupus erythematosus: potential for personalized treatment. | |
| M=92 | |
| - expression and localization of nlrp4g in mouse preimplantation embryo. | |
| - localization and expression of histone h2a variants during mouse oogenesis and preimplantation embryo development. | |
| M=91 | |
| - circadian control of global transcription. | |
| - chip-seq and rna-seq methods to study circadian control of transcription in mammals. | |
| M=90 | |
| - continuous blockade of cxcr4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells. | |
| - ex vivo expansion of hematopoietic stem cells. | |
| M=90 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - mouse genome editing using the crispr/cas system. | |
| M=90 | |
| - divergence patterns of genic copy number variation in natural populations of the house mouse (mus musculus domesticus) reveal three conserved genes with major population-specific expansions. | |
| - genomic copy number variation in mus musculus. | |
| M=89 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - role of the dna repair glycosylase ogg1 in the activation of murine splenocytes. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=89 | |
| - cellular reprogramming, genome editing, and alternative crispr cas9 technologies for precise gene therapy of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - male infertility is responsible for nearly half of the extinction observed in the mouse collaborative cross. | |
| - genomes of the mouse collaborative cross. | |
| M=89 | |
| - muscle-specific crispr/cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - the potential role of 8-oxoguanine dna glycosylase-driven dna base excision repair in exercise-induced asthma. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - exploring novel candidate genes from the mouse genome informatics database: potential implications for avian migration research. | |
| - mouse genome database 2016. | |
| M=89 | |
| - mouse genome database 2016. | |
| - dbsuper: a database of super-enhancers in mouse and human genome. | |
| M=89 | |
| - mouse genome database 2016. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=89 | |
| - mouse genome database 2016. | |
| - mouse genome database: from sequence to phenotypes and disease models. | |
| M=89 | |
| - mouse genome database 2016. | |
| - the mouse genome database (mgd): facilitating mouse as a model for human biology and disease. | |
| M=89 | |
| - single-step generation of conditional knockout mouse embryonic stem cells. | |
| - rapid knockout and reporter mouse line generation and breeding colony establishment using eucomm conditional-ready embryonic stem cells: a case study. | |
| M=89 | |
| - a central role of trax in the atm-mediated dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=88 | |
| - combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models. | |
| - development of humanized mice in the age of genome editing. | |
| M=88 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=88 | |
| - genome editing in mouse and rat by electroporation. | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| M=88 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - [genome editing in mouse with crispr/cas system]. | |
| M=88 | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| - mouse genome editing using the crispr/cas system. | |
| M=87 | |
| - replication study: melanoma genome sequencing reveals frequent prex2 mutations. | |
| - registered report: melanoma genome sequencing reveals frequent prex2 mutations. | |
| M=87 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=87 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=87 | |
| - genome editing in mice using tale nucleases. | |
| - genome editing in mouse spermatogonial stem/progenitor cells using engineered nucleases. | |
| M=86 | |
| - hotspots of de novo point mutations in induced pluripotent stem cells. | |
| - the number of point mutations in induced pluripotent stem cells and nuclear transfer embryonic stem cells depends on the method and somatic cell type used for their generation. | |
| M=86 | |
| - data on the effect of in utero exposure to polycyclic aromatic hydrocarbons on genome-wide patterns of dna methylation in lung tissues. | |
| - dna methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons. | |
| M=86 | |
| - crispr/cas9 - mediated precise targeted integration in vivo using a double cut donor with short homology arms. | |
| - homology-mediated end joining-based targeted integration using crispr/cas9. | |
| M=86 | |
| - effective biomedical document classification for identifying publications relevant to the mouse gene expression database (gxd). | |
| - the mouse gene expression database (gxd): 2017 update. | |
| M=86 | |
| - initial characterization of behavior and ketamine response in a mouse knockout of the post-synaptic effector gene anks1b. | |
| - the eif2a knockout mouse. | |
| M=86 | |
| - single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types. | |
| - evolution of the unspliced transcriptome. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - exome-wide single-base substitutions in tissues and derived cell lines of the constitutive fhit knockout mouse. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - beyond knockouts: the international knockout mouse consortium delivers modular and evolving tools for investigating mammalian genes. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - utilising the resources of the international knockout mouse consortium: the australian experience. | |
| M=86 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - gene therapies that restore dystrophin expression for the treatment of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=86 | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=86 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - application of comparative transcriptional genomics to identify molecular targets for pediatric ibd. | |
| M=86 | |
| - excavating the genome: large-scale mutagenesis screening for the discovery of new mouse models. | |
| - enu mutagenesis in the mouse. | |
| M=86 | |
| - enu mutagenesis in the mouse. | |
| - mouse enu mutagenesis to understand immunity to infection: methods, selected examples, and perspectives. | |
| M=86 | |
| - molecular and cellular regulation of skeletal myogenesis. | |
| - transcriptional regulation of important cellular processes in skeletal myogenesis through interferon-γ. | |
| M=85 | |
| - landscape of dna methylation on the marsupial x. | |
| - influence of the prader-willi syndrome imprinting center on the dna methylation landscape in the mouse brain. | |
| M=85 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| M=85 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| M=85 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - functional validation of tensin2 sh2-ptb domain by crispr/cas9-mediated genome editing. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - crispr/cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - generation of an oocyte-specific cas9 transgenic mouse for genome editing. | |
| M=85 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - self-cloning crispr. | |
| M=85 | |
| - self-cloning crispr. | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| M=85 | |
| - self-cloning crispr. | |
| - cloning-free crispr. | |
| M=85 | |
| - the potential role of 8-oxoguanine dna glycosylase-driven dna base excision repair in exercise-induced asthma. | |
| - the role of 8-oxoguanine dna glycosylase-1 in inflammation. | |
| M=85 | |
| - the role of mdm2 amplification and overexpression in tumorigenesis. | |
| - gene amplification-associated overexpression of the rna editing enzyme adar1 enhances human lung tumorigenesis. | |
| M=85 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| - cloning-free crispr. | |
| M=85 | |
| - assessment of microrna expression in mouse epididymal epithelial cells and spermatozoa by next generation sequencing. | |
| - next generation sequencing analysis reveals segmental patterns of microrna expression in mouse epididymal epithelial cells. | |
| M=85 | |
| - transcriptional response in mouse thyroid tissue after 211at administration: effects of absorbed dose, initial dose-rate and time after administration. | |
| - transcriptional response in normal mouse tissues after i.v. (211)at administration - response related to absorbed dose, dose rate, and time. | |
| M=85 | |
| - syntaxin-binding protein stxbp5 inhibits endothelial exocytosis and promotes platelet secretion. | |
| - platelet secretion and hemostasis require syntaxin-binding protein stxbp5. | |
| M=84 | |
| - amino acid substitutions associated with avian h5n6 influenza a virus adaptation to mice. | |
| - amino acid substitutions involved in the adaptation of a novel highly pathogenic h5n2 avian influenza virus in mice. | |
| M=84 | |
| - genome editing in mouse and rat by electroporation. | |
| - efficient crispr/cas9-mediated genome editing in mice by zygote electroporation of nuclease. | |
| M=84 | |
| - p53 and tap63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - collaborative cross and diversity outbred data resources in the mouse phenome database. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - informatics resources for the collaborative cross and related mouse populations. | |
| M=84 | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| - complete genome sequence of turicibacter sp. strain h121, isolated from the feces of a contaminated germ-free mouse. | |
| M=84 | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| - the genetic architecture of nafld among inbred strains of mice. | |
| M=84 | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| - crispr-cas9 knockin mice for genome editing and cancer modeling. | |
| M=83 | |
| - pd-l1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome informatics (mgi) resource: genetic, genomic, and biological knowledgebase for the laboratory mouse. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - effects of expressing human t-cell leukemia virus type 1 (htlv-i) oncoprotein tax on dok1, dok2 and dok3 gene expression in mice. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - human t-cell leukemia virus type 1 (htlv-1) tax requires cadm1/tslc1 for inactivation of the nf-κb inhibitor a20 and constitutive nf-κb signaling. | |
| M=83 | |
| - shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the united states. | |
| - zinc and diabetes. | |
| M=83 | |
| - a five-repeat micro-dystrophin gene ameliorated dystrophic phenotype in the severe dba/2j-mdx model of duchenne muscular dystrophy. | |
| - jagged 1 rescues the duchenne muscular dystrophy phenotype. | |
| M=83 | |
| - engineered epidermal progenitor cells can correct diet-induced obesity and diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - tex19.1 promotes spo11-dependent meiotic recombination in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=83 | |
| - identification and characterization of a foxa2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls gckr expression in liver cells. | |
| - zinc and diabetes. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=83 | |
| - expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion. | |
| - zinc and diabetes. | |
| M=83 | |
| - targeted dna methylation in pericentromeres with genome editing-based artificial dna methyltransferase. | |
| - editing dna methylation in the mammalian genome. | |
| M=83 | |
| - using hescs to probe the interaction of the diabetes-associated genes cdkal1 and mt1e. | |
| - zinc and diabetes. | |
| M=83 | |
| - dna modifications and alzheimer's disease. | |
| - modifiers and readers of dna modifications and their impact on genome structure, expression, and stability in disease. | |
| M=83 | |
| - the zinc finger e-box-binding homeobox 1 (zeb1) promotes the conversion of mouse fibroblasts into functional neurons. | |
| - chemical conversion of mouse fibroblasts into functional dopaminergic neurons. | |
| M=83 | |
| - genetic and small molecule disruption of the aid/rad51 axis similarly protects nonobese diabetic mice from type 1 diabetes through expansion of regulatory b lymphocytes. | |
| - zinc and diabetes. | |
| M=83 | |
| - long-term alterations to dna methylation as a biomarker of prenatal alcohol exposure: from mouse models to human children with fetal alcohol spectrum disorders. | |
| - associative dna methylation changes in children with prenatal alcohol exposure. | |
| M=83 | |
| - genetics of obesity: can an old dog teach us new tricks? | |
| - systems genetics of obesity. | |
| M=83 | |
| - the transcription factor nfatc2 regulates β-cell proliferation and genes associated with type 2 diabetes in mouse and human islets. | |
| - zinc and diabetes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - visualization of results from systems genetics studies in chromosomal context. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a suite of tools for biologists that improve accessibility and visualization of large systems genetics datasets: applications to the hybrid mouse diversity panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - defining the influence of germline variation on metastasis using systems genetics approaches. | |
| M=83 | |
| - systems genetics of obesity. | |
| - the hybrid mouse diversity panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics of intravenous cocaine self-administration in the bxd recombinant inbred mouse panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - application of quantitative metabolomics in systems genetics in rodent models of complex phenotypes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a systems genetics study of swine illustrates mechanisms underlying human phenotypic traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics identifies sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus. | |
| M=83 | |
| - emerging roles of glis3 in neonatal diabetes, type 1 and type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - differential gene dosage effects of diabetes-associated gene glis3 in pancreatic β cell differentiation and function. | |
| - zinc and diabetes. | |
| M=83 | |
| - transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms. | |
| - enu mutagenesis in the mouse. | |
| M=83 | |
| - inhibition of dna methyltransferase 1 increases nuclear receptor subfamily 4 group a member 1 expression and decreases blood glucose in type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - microinjection-based generation of mutant mice with a double mutation and a 0.5 mb deletion in their genome by the crispr/cas9 system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=83 | |
| - an integrative study identifies kcnc2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the korean population. | |
| - zinc and diabetes. | |
| M=83 | |
| - structural organization of the inactive x chromosome in the mouse. | |
| - bipartite structure of the inactive mouse x chromosome. | |
| M=83 | |
| - zinc and diabetes. | |
| - serotonin as a new therapeutic target for diabetes mellitus and obesity. | |
| M=83 | |
| - zinc and diabetes. | |
| - unexpected partial correction of metabolic and behavioral phenotypes of alzheimer's app/psen1 mice by gene targeting of diabetes/alzheimer's-related sorcs1. | |
| M=83 | |
| - zinc and diabetes. | |
| - type 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic association of long-chain acyl-coa synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis. | |
| M=83 | |
| - zinc and diabetes. | |
| - a20 inhibits β-cell apoptosis by multiple mechanisms and predicts residual β-cell function in type 1 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the nod mouse reveals significant gene enrichment on chromosomes 6 and 7. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptpn22 and cd2 variations are associated with altered protein expression and susceptibility to type 1 diabetes in nonobese diabetic mice. | |
| M=83 | |
| - zinc and diabetes. | |
| - phenotypic characterization of mice carrying homozygous deletion of klf11, a gene in which mutations cause human neonatal and mody vii diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptprd silencing by dna hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - the pathogenic role of persistent milk signaling in mtorc1- and milk-microrna-driven type 2 diabetes mellitus. | |
| M=83 | |
| - zinc and diabetes. | |
| - shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities. | |
| M=83 | |
| - sequence diversity, intersubgroup relationships, and origins of the mouse leukemia gammaretroviruses of laboratory and wild mice. | |
| - origins of the endogenous and infectious laboratory mouse gammaretroviruses. | |
| M=83 | |
| - rag2 and xlf/cernunnos interplay reveals a novel role for the rag complex in dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - nuclear localization of the dna repair scaffold xrcc1: uncovering the functional role of a bipartite nls. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - genomic copy number variation in mus musculus. | |
| - connecting anxiety and genomic copy number variation: a genome-wide analysis in cd-1 mice. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - piggybac transposon-based insertional mutagenesis in mouse haploid embryonic stem cells. | |
| M=82 | |
| - genome-wide discovery of long intergenic noncoding rnas and their epigenetic signatures in the rat. | |
| - mutations in the noncoding genome. | |
| M=82 | |
| - replication stress in hematopoietic stem cells in mouse and man. | |
| - a short g1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. | |
| M=82 | |
| - complete genome sequence of a strain of bifidobacterium pseudolongum isolated from mouse feces and associated with improved organ transplant outcome. | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| M=82 | |
| - highly variable genomic landscape of endogenous retroviruses in the c57bl/6j inbred strain, depending on individual mouse, gender, organ type, and organ location. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - a modifier of huntington's disease onset at the mlh1 locus. | |
| - chromosome substitution strain assessment of a huntington's disease modifier locus. | |
| M=82 | |
| - a14 comprehensive characterisation and evolutionary analysis of endogenous retroviruses in the mouse genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=82 | |
| - the hope and hype of crispr-cas9 genome editing: a review. | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| M=82 | |
| - detection of rna polymerase ii in mouse embryos during zygotic genome activation using immunocytochemistry. | |
| - rna fish to study zygotic genome activation in early mouse embryos. | |
| M=82 | |
| - identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts. | |
| - generation of integration-free induced neural stem cells from mouse fibroblasts. | |
| M=82 | |
| - comparative dynamics of 5-methylcytosine reprogramming and tet family expression during preimplantation mammalian development in mouse and sheep. | |
| - maternal sin3a regulates reprogramming of gene expression during mouse preimplantation development. | |
| M=82 | |
| - targeting of heat shock protein hspa6 (hsp70b') to the periphery of nuclear speckles is disrupted by a transcription inhibitor following thermal stress in human neuronal cells. | |
| - localization of heat shock protein hspa6 (hsp70b') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9 mediated genome editing in es cells and its application for chimeric analysis in mice. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9-mediated insertion of loxp sites in the mouse dock7 gene provides an effective alternative to use of targeted embryonic stem cells. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - generating crispr/cas9 mediated monoallelic deletions to study enhancer function in mouse embryonic stem cells. | |
| M=82 | |
| - integration and fixation preferences of human and mouse endogenous retroviruses uncovered with functional data analysis. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - precision cancer mouse models through genome editing with crispr-cas9. | |
| M=82 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=82 | |
| - improved genome editing efficiency and flexibility using modified oligonucleotides with talen and crispr-cas9 nucleases. | |
| - genome editing in mice using tale nucleases. | |
| M=82 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - insertion of sequences at the original provirus integration site of mouse rosa26 locus using the crispr/cas9 system. | |
| M=82 | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=82 | |
| - the role of human endogenous retroviruses in brain development and function. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - genomic landscapes of endogenous retroviruses unveil intricate genetics of conventional and genetically-engineered laboratory mouse strains. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - trim33 binds and silences a class of young endogenous retroviruses in the mouse testis; a novel component of the arms race between retrotransposons and the host genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - towards autotrophic tissue engineering: photosynthetic gene therapy for regeneration. | |
| - photosynthetic biomaterials: a pathway towards autotrophic tissue engineering. | |
| M=82 | |
| - mutations in the noncoding genome. | |
| - assessing recent selection and functionality at long noncoding rna loci in the mouse genome. | |
| M=82 | |
| - mutations in the noncoding genome. | |
| - generation of site-specific mutations in the rat genome via crispr/cas9. | |
| M=82 | |
| - comprehensive dna methylation analysis of retrotransposons in male germ cells. | |
| - locus-specific dna methylation analysis of retrotransposons in es, somatic and cancer cells using high-throughput targeted repeat element bisulfite sequencing. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the histone methyltransferase setdb1 represses endogenous and exogenous retroviruses in b lymphocytes. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the krab zinc finger protein zfp809 is required to initiate epigenetic silencing of endogenous retroviruses. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the decline of human endogenous retroviruses: extinction and survival. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - setdb1 is required for germline development and silencing of h3k9me3-marked endogenous retroviruses in primordial germ cells. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the distribution of insertionally polymorphic endogenous retroviruses in breast cancer patients and cancer-free controls. | |
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